Pla2g2e | phospholipase A2, group IIE
Physiological systems
18 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Hematopoietic system Cardiovascular system
15 No significant impact
6 Not tested
Data collections
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:70Adult tissues
0Embryo tissues
increased circulating alkaline phosphatase level | 1 supporting dataset | Pla2g2etm1b(EUCOMM)Wtsi | homozygote | Early adult | 1.49x10-5 | ||
increased red blood cell distribution width | 1 supporting dataset | Pla2g2etm1b(EUCOMM)Wtsi | homozygote | Early adult | 2.33x10-8 | ||
increased cardiac stroke volume | 1 supporting dataset | Pla2g2etm1b(EUCOMM)Wtsi | homozygote | Early adult | 2.37x10-6 | ||
dilated heart left ventricle | 1 supporting dataset | Pla2g2etm1b(EUCOMM)Wtsi | homozygote | Early adult | 9.97x10-5 |
| | | | | | | | | |
adrenal gland | heterozygote | n/a | 0% (0/1) | 0.7% (4/570) |
aorta | heterozygote | n/a | 0% (0/1) | 0.19% (1/533) |
blood | heterozygote | n/a | 0% (0/1) | 0% (0/17) |
bone | heterozygote | n/a | 0% (0/1) | 0% (0/394) |
bone marrow | heterozygote | n/a | 0% (0/1) | 0% (0/22) |
brain | heterozygote | n/a | 0% (0/1) | 0.86% (5/579) |
brainstem | heterozygote | n/a | 0% (0/1) | 0.41% (2/490) |
brown adipose tissue | heterozygote | n/a | 0% (0/1) | 0% (0/588) |
cartilage tissue | heterozygote | n/a | 0% (0/1) | 0.22% (1/454) |
cecum | heterozygote | n/a | 0% (0/1) | 7.75% (22/284) |
External links
No external links available for Pla2g2e.
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Pla2g2etm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Pla2g2etm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
Pla2g2etm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |