Gene: Ppp2r5c

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Name
protein phosphatase 2, regulatory subunit B', gamma
MGI ID
MGI:1349475
Synonyms
Band 8A 2610043M05Rik 2700063L20Rik D12Bwg0916e B56/PP2A gamma
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
enlarged heart Ppp2r5cem1(IMPC)Mbp HOM Early adult 0.00
decreased fasting circulating glucose level Ppp2r5cem1(IMPC)Mbp HOM Early adult 6.06×10-07
decreased startle reflex Ppp2r5cem1(IMPC)Mbp HOM Early adult 7.16×10-26
increased monocyte cell number Ppp2r5cem1(IMPC)Mbp HOM Early adult 6.36×10-05
irregularly shaped pupil Ppp2r5cem1(IMPC)Mbp HOM Early adult 3.94×10-15
enlarged spleen Ppp2r5cem1(IMPC)Mbp HOM Early adult 0.00
increased blood urea nitrogen level Ppp2r5cem1(IMPC)Mbp HOM   Early adult 6.46×10-08
abnormal heart morphology Ppp2r5cem1(IMPC)Mbp HOM Early adult 0.00
enlarged lymph nodes Ppp2r5cem1(IMPC)Mbp HOM Early adult 0.00
increased circulating alkaline phosphatase level Ppp2r5cem1(IMPC)Mbp HOM   Early adult 1.63×10-05
impaired contextual conditioning behavior Ppp2r5cem1(IMPC)Mbp HOM Early adult 3.02×10-06
increased mean corpuscular hemoglobin Ppp2r5cem1(IMPC)Mbp HOM Early adult 1.43×10-06
increased neutrophil cell number Ppp2r5cem1(IMPC)Mbp HOM Early adult 3.09×10-05
increased mean corpuscular volume Ppp2r5cem1(IMPC)Mbp HOM Early adult 4.12×10-06
increased total body fat amount Ppp2r5cem1(IMPC)Mbp HOM Early adult 9.73×10-06
increased heart weight Ppp2r5cem1(IMPC)Mbp HOM Early adult 4.75×10-07
abnormal lymph node morphology Ppp2r5cem1(IMPC)Mbp HOM Early adult 0.00
abnormal placement of pupils Ppp2r5cem1(IMPC)Mbp HOM Early adult 1.15×10-10
decreased lean body mass Ppp2r5cem1(IMPC)Mbp HOM Early adult 1.10×10-05
abnormal spleen morphology Ppp2r5cem1(IMPC)Mbp HOM Early adult 0.00
impaired cued conditioning behavior Ppp2r5cem1(IMPC)Mbp HOM Early adult 2.74×10-09

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 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
30 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Eye with optic nerve - organ specific developmental defect Ppp2r5cem1(IMPC)Mbp HOM Early adult
Eye with optic nerve - developmental and structural abnormality Ppp2r5cem1(IMPC)Mbp HOM Early adult

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MGI Allele Allele Type Produced
Ppp2r5ctm256213(L1L2_Bact_P) Targeting vectors
Ppp2r5ctm256213(L1L2_gt0_Del_LacZ) Targeting vectors
Ppp2r5ctm256213(pL1L2_frt15_BetactinBSD_frt14_neo_Rox) Targeting vectors
Ppp2r5cem1(IMPC)Mbp Exon Deletion Mice, Tissue

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