Gene: Cops7a

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Name
COP9 signalosome subunit 7A
MGI ID
MGI:1349400
Synonyms
COP9 complex S7a D6Ertd35e
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased heart weight Cops7atm1b(KOMP)Mbp HOM   Early adult 5.45×10-05
hydrometra Cops7atm1b(KOMP)Mbp HOM Early adult 0.00
decreased startle reflex Cops7atm1b(KOMP)Mbp HOM Early adult 9.95×10-05
small thymus Cops7atm1b(KOMP)Mbp HOM Early adult 0.00
decreased prepulse inhibition Cops7atm1b(KOMP)Mbp HOM   Early adult 2.10×10-06
enlarged heart Cops7atm1b(KOMP)Mbp HOM Early adult 0.00
improved glucose tolerance Cops7atm1b(KOMP)Mbp HOM Early adult 1.85×10-10
abnormal spleen morphology Cops7atm1b(KOMP)Mbp HOM Early adult 0.00
small spleen Cops7atm1b(KOMP)Mbp HOM Early adult 0.00
abnormal heart morphology Cops7atm1b(KOMP)Mbp HOM Early adult 0.00
abnormal eye morphology Cops7atm1b(KOMP)Mbp HOM Early adult 0.00
abnormal urinary bladder morphology Cops7atm1b(KOMP)Mbp HOM Early adult 0.00
abnormal thymus morphology Cops7atm1b(KOMP)Mbp HOM Early adult 0.00
abnormal uterus morphology Cops7atm1b(KOMP)Mbp HOM Early adult 0.00

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583)  (2/2)  Section images
Aorta 2 No  (1/583)  (2/2)  Section images
Blood 2 No N/A
Bone marrow 2 No N/A
Brain 2 No  (4/583) N/A
Brainstem 2 No  (2/583) N/A
Brown adipose tissue 2 No  (1/2)  Section images
Cartilage tissue 2 No  (1/583) N/A
Cecum 2 No  (12/371)  (2/2)  Section images
Cerebellum 2 No  (3/583)  (1/2)  Section images
Cerebral cortex 2 No  (2/583) N/A
Chest bone 2 No N/A
Colon 2 No  (12/127)  (2/2)  Section images
Diaphragm 2 No  (1/2)  Section images
Duodenum 2 No  (2/127)  (2/2)  Section images
Epididymis 2 No  (18/132)  (1/2)  Section images
Esophagus 2 No  (7/407)  (1/2)  Section images
Eye 2 No  (2/2)  Section images
Gall bladder 2 No N/A
Gonadal fat pad 2 No  (1/2)  Section images
Harderian gland 2 No  (2/2)  Section images
Heart 2 No  (2/583) N/A
Hindlimb 2 No N/A
Hippocampus 2 No  (3/583) N/A
Hypothalamus 2 No  (2/583) N/A
Ileum 2 No  (14/127)  (2/2)  Section images
Jejunum 2 No  (6/127) N/A
Kidney 2 No  (21/583)  (2/2)  Section images
Large intestine 2 No  (10/583) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/583) N/A
Lung 2 No  (2/583)  (2/2)  Section images
Lymph node 2 No  (1/583) N/A
Mammary gland 2 No N/A
Mesenteric adipose tissue 2 No  (2/2)  Section images
Mesenteric lymph node 2 No N/A
Midbrain 2 No  (2/2)  Section images
Olfactory lobe 2 No  (2/583)  (1/2)  Section images
Ovary 2 No  (1/583) N/A
Oviduct 2 No  (1/2)  Section images
Pancreas 2 No  (5/583) N/A
Parathyroid gland 2 No  (1/563) N/A
Parotid gland 2 No N/A
Penis 2 No  (1/2)  Section images
Peripheral nervous system 2 No  (2/583) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/583)  (2/2)  Section images
Prostate gland 2 No  (12/583)  (1/2)  Section images
Quadriceps 2 No  (1/2)  Section images
Sciatic nerve 2 No N/A
Skeletal muscle 2 No N/A
Skin 2 No  (1/583)  (2/2)  Section images
Small intestine 2 No  (9/583) N/A
Spinal cord 2 No  (3/583)  (2/2)  Section images
Spleen 2 No  (3/583) N/A
Stomach 2 No  (13/583)  (2/2)  Section images
Stomach pyloric region 2 No N/A
Striatum 2 No  (3/583) N/A
Sublingual gland 2 No N/A
Submandibular gland 2 No  (2/130) N/A
Testis 2 No  (6/583)  (1/2)  Section images
Thymus 2 No  (1/583) N/A
Thyroid gland 2 No  (17/583) N/A
Tongue 2 No  (5/127)  (1/2)  Section images
Trachea 2 No  (3/583)  (1/2)  Section images
Trigeminal V nerve 2 No  (2/2)  Section images
Urinary bladder 2 No  (2/2)  Section images
Uterus 2 No  (1/2)  Section images
Vagina 2 No N/A
Vas deferens 2 No  (15/382)  (1/2)  Section images
Vascular system 2 No N/A
Vesicular gland 2 No  (1/2)  Section images
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

Adult LacZ: LacZ Images Section
102 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Cops7atm1b(KOMP)Mbp Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Cops7atm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Cops7atm1a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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