Genes Phenotypes

Gene: Sdc4

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Name
syndecan 4
MGI ID
MGI:1349164
Synonyms
syndecan-4 ryudocan Synd4 S4
Viability
Homozygous - Viable
View
N/A
Other links
MGI   Ensembl  
Significant phenotypes (5) Measurements chart (230) All data table (577)
Expression & images (67) Disease models (0) Histopathology (2) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
increased red blood cell distribution width Sdc4tm2b(KOMP)Wtsi HOM postnatal 2.61×10-06
mydriasis Sdc4tm2b(KOMP)Wtsi HET postnatal 1.31×10-07
decreased circulating serum albumin level Sdc4tm2b(KOMP)Wtsi HOM postnatal 3.24×10-06
decreased lymphocyte cell number Sdc4tm2b(KOMP)Wtsi HOM postnatal 8.13×10-07
abnormal retinal blood vessel morphology Sdc4tm2b(KOMP)Wtsi HET postnatal 7.63×10-05

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Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Wholemount images
Aorta 2 No  (2/2)  Wholemount images
Bone 2 No  (2/2)  Wholemount images
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No  (2/2)  Wholemount images
Brown adipose tissue 2 No  (2/2)  Wholemount images
Cartilage tissue 2 No  (2/2)  Wholemount images
Cerebellum 2 No  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/2)  Wholemount images
Esophagus 2 No  (7/415)  (2/2)  Wholemount images
Eye 2 No  (2/2)  Wholemount images
Gall bladder 2 No  (2/2)  Wholemount images
Heart 2 No  (2/2)  Wholemount images
Hippocampus 2 No  (2/2)  Wholemount images
Hypothalamus 2 No  (2/2)  Wholemount images
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584)  (2/2)  Wholemount images
Liver 2 No  (2/2)  Wholemount images
Lower urinary tract 2 No  (2/2)  Wholemount images
Lung 2 No  (2/2)  Wholemount images
Lymph node 2 No  (2/2)  Wholemount images
Mammary gland 2 No  (1/2)  Wholemount images
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No  (2/2)  Wholemount images
Ovary 2 No  (1/584)  (1/2)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/584)  (2/2)  Wholemount images
Parathyroid gland 2 No  (2/2)  Wholemount images
Peripheral nervous system 2 No  (2/2)  Wholemount images
Peyer's patch 2 No  (2/2)  Wholemount images
Pituitary gland 2 No  (2/2)  Wholemount images
Prostate gland 2 No  (12/584)  (1/2)  Wholemount images
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Wholemount images
Small intestine 2 No  (9/584)  (2/2)  Wholemount images
Spinal cord 2 No  (2/2)  Wholemount images
Spleen 2 No  (2/584)  (2/2)  Wholemount images
Stomach 2 No  (12/584)  (2/2)  Wholemount images
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No  (2/2)  Wholemount images
Thyroid gland 2 No  (15/584)  (2/2)  Wholemount images
Trachea 2 No  (2/2)  Wholemount images
Uterus 2 No  (1/2)  Wholemount images
Vascular system 2 No  (2/2)  Wholemount images
White adipose tissue 2 No N/A
LacZ Wholemount Images
adipose tissue (1)
Brown adipose tissue expression
MA:0000057
cardiovascular system (3)
Cartilage tissue expression
Bone expression
Vascular System expression
MA:0000104
MA:0001459
MA:0002718
digestive system (5)
Large Intestine expression
MA:0000333
endocrine system (2)
Adrenal gland expression
MA:0000116
exocrine system (2)
Lower Urinary Tract expression
Prostate gland tissue not available
MA:0002636
MA:0000404
immune system (4)
Lymph Node expression
MA:0000139
integumental system (2)
Mammary gland tissue not available
MA:0000145
musculoskeletal system (1)
Cartilage tissue expression
Bone expression
Vascular System expression
MA:0000104
MA:0001459
MA:0002718
nervous system (5)
Cerebral Cortex expression
Striatum expression
Hippocampus expression
Brain expression
MA:0000185
MA:0000891
MA:0000191
MA:0000168
postnatal mouse (28)
Adrenal gland expression
MA:0000116
reproductive system (3)
Lower Urinary Tract expression
Prostate gland tissue not available
MA:0002636
MA:0000404
respiratory system (3)
Lung expression
MA:0000415
sensory organ (1)
Eye expression
MA:0000261
set of connective tissues (3)
Brown adipose tissue expression
MA:0000057
trunk (16)
Adrenal gland expression
MA:0000116
urinary system (2)
Kidney expression
MA:0000368
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485) N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485)  (4/4) N/A
Eye 2  (1/485)  (2/4) N/A
Foot 2  (1/485)  (2/4) N/A
Forebrain 2  (1/485) N/A
Forelimb 2  (1/485)  (2/4) N/A
Hand 2  (1/485)  (2/4) N/A
Head 2  (5/485)  (3/4) N/A
Heart 2  (1/485)  (2/4) N/A
Hindbrain 2  (6/485) N/A
Hindlimb 2  (1/485)  (2/4) N/A
Liver 2  (1/485)  (1/4) N/A
Lung 2  (1/485)  (1/4) N/A
Mandibular process 2  (1/485) N/A
Maxillary process 2  (1/485) N/A
Midbrain 2  (1/485) N/A
Oral cavity 2  (1/485)  (1/4) N/A
Skin 2  (1/485) N/A
Tail 2  (1/485)  (2/4) N/A
Tail somite 2  (1/485) N/A

 Associated Images

Echo: M-Mode Images
60 Images
Adult LacZ: LacZ Images Wholemount
28 Images
X-ray: XRay Images Dorso Ventral
18 Images
X-ray: XRay Images Lateral Orientation
18 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
18 Images
Embryo LacZ: LacZ images wholemount
8 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
9 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Stomach - MPATH diagnostic term epithelial hyperplasia Sdc4tm2b(KOMP)Wtsi HOM postnatal
Stomach - hyperplasia Sdc4tm2b(KOMP)Wtsi HOM postnatal

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Sdc4tm2a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Sdc4tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Sdc4tm2b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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