Genes Phenotypes

Gene: Sdc4

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Name
syndecan 4
MGI ID
MGI:1349164
Synonyms
ryudocan Synd4 S4 syndecan-4
Viability
Homozygous - Viable
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (5) Measurements chart (231) All data table (774)
Expression & images (67) Disease models (0) Histopathology (2) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
decreased circulating serum albumin level Sdc4tm2b(KOMP)Wtsi HOM Early adult 3.97×10-06
increased red blood cell distribution width Sdc4tm2b(KOMP)Wtsi HOM Early adult 2.77×10-06
decreased lymphocyte cell number Sdc4tm2b(KOMP)Wtsi HOM Early adult 8.30×10-07
abnormal retinal blood vessel morphology Sdc4tm2b(KOMP)Wtsi HET Early adult 3.27×10-05
mydriasis Sdc4tm2b(KOMP)Wtsi HET Early adult 1.04×10-07

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Wholemount images
Aorta 2 No  (2/2)  Wholemount images
Bone 2 No  (2/2)  Wholemount images
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No  (2/2)  Wholemount images
Brown adipose tissue 2 No  (2/2)  Wholemount images
Cartilage tissue 2 No  (2/2)  Wholemount images
Cerebellum 2 No  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/2)  Wholemount images
Esophagus 2 No  (7/415)  (2/2)  Wholemount images
Eye 2 No  (2/2)  Wholemount images
Gall bladder 2 No  (2/2)  Wholemount images
Heart 2 No  (2/2)  Wholemount images
Hippocampus 2 No  (2/2)  Wholemount images
Hypothalamus 2 No  (2/2)  Wholemount images
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584)  (2/2)  Wholemount images
Liver 2 No  (2/2)  Wholemount images
Lower urinary tract 2 No  (2/2)  Wholemount images
Lung 2 No  (2/2)  Wholemount images
Lymph node 2 No  (2/2)  Wholemount images
Mammary gland 2 No  (1/2)  Wholemount images
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No  (2/2)  Wholemount images
Ovary 2 No  (1/584)  (1/2)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/584)  (2/2)  Wholemount images
Parathyroid gland 2 No  (2/2)  Wholemount images
Peripheral nervous system 2 No  (2/2)  Wholemount images
Peyer's patch 2 No  (2/2)  Wholemount images
Pituitary gland 2 No  (2/2)  Wholemount images
Prostate gland 2 No  (12/584)  (1/2)  Wholemount images
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Wholemount images
Small intestine 2 No  (9/584)  (2/2)  Wholemount images
Spinal cord 2 No  (2/2)  Wholemount images
Spleen 2 No  (2/584)  (2/2)  Wholemount images
Stomach 2 No  (12/584)  (2/2)  Wholemount images
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No  (2/2)  Wholemount images
Thyroid gland 2 No  (15/584)  (2/2)  Wholemount images
Trachea 2 No  (2/2)  Wholemount images
Uterus 2 No  (1/2)  Wholemount images
Vascular system 2 No  (2/2)  Wholemount images
White adipose tissue 2 No N/A
LacZ Wholemount Images
adipose tissue (1)
Brown adipose tissue expression
MA:0000057
cardiovascular system (3)
Cartilage tissue expression
Bone expression
Vascular System expression
MA:0000104
MA:0001459
MA:0002718
digestive system (5)
Large Intestine expression
MA:0000333
endocrine system (2)
Adrenal gland expression
MA:0000116
exocrine system (2)
Lower Urinary Tract expression
Prostate gland tissue not available
MA:0002636
MA:0000404
immune system (4)
Lymph Node expression
MA:0000139
integumental system (2)
Mammary gland tissue not available
MA:0000145
musculoskeletal system (1)
Cartilage tissue expression
Bone expression
Vascular System expression
MA:0000104
MA:0001459
MA:0002718
nervous system (5)
Cerebral Cortex expression
Striatum expression
Hippocampus expression
Brain expression
MA:0000185
MA:0000891
MA:0000191
MA:0000168
postnatal mouse (28)
Adrenal gland expression
MA:0000116
reproductive system (3)
Lower Urinary Tract expression
Prostate gland tissue not available
MA:0002636
MA:0000404
respiratory system (3)
Lung expression
MA:0000415
sensory organ (1)
Eye expression
MA:0000261
set of connective tissues (3)
Brown adipose tissue expression
MA:0000057
trunk (16)
Adrenal gland expression
MA:0000116
urinary system (2)
Kidney expression
MA:0000368
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/504) N/A
Ear 2  (1/504) N/A
Embryo 2  (1/505)  (4/4) N/A
Eye 2  (1/504)  (2/4) N/A
Foot 2  (1/504)  (2/4) N/A
Forebrain 2  (1/504) N/A
Forelimb 2  (1/504)  (2/4) N/A
Hand 2  (1/503)  (2/4) N/A
Head 2  (5/504)  (3/4) N/A
Heart 2  (1/504)  (2/4) N/A
Hindbrain 2  (6/504) N/A
Hindlimb 2  (1/503)  (2/4) N/A
Liver 2  (1/504)  (1/4) N/A
Lung 2  (1/500)  (1/4) N/A
Mandibular process 2  (1/504) N/A
Maxillary process 2  (1/504) N/A
Midbrain 2  (1/504) N/A
Oral cavity 2  (1/504)  (1/4) N/A
Skin 2  (1/504) N/A
Tail 2  (1/504)  (2/4) N/A
Tail somite 2  (1/504) N/A

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
18 Images
X-ray: XRay Images Whole Body Lateral Orientation
18 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
18 Images
Adult LacZ: LacZ Images Wholemount
28 Images
Embryo LacZ: LacZ images wholemount
8 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
9 Images
Echo: M-Mode Images
60 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Stomach - hyperplasia Sdc4tm2b(KOMP)Wtsi HOM Early adult
Stomach - MPATH diagnostic term epithelial hyperplasia Sdc4tm2b(KOMP)Wtsi HOM Early adult

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Sdc4tm2b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Sdc4tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Sdc4tm2a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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