Zfp260 | zinc finger protein 260

GeneMGI:1347071Synonyms: Zfp63, Ozrf1, +1 more

Physiological systems

19 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Limbs/digits/tail Nervous system Hematopoietic system Skeleton Mortality/aging

12 No significant impact

5 Not tested

Gene metrics:10Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
60Embryo tissues

Phenotypes

decreased prepulse inhibition1 supporting datasetZfp260tm1b(NCOM)MfgcheterozygoteEarly adult8.26x10-5 
decreased lymphocyte cell number1 supporting datasetZfp260tm1b(NCOM)MfgcheterozygoteEarly adult2.45x10-5 
preweaning lethality, incomplete penetrance2 supporting datasetsZfp260tm1b(NCOM)MfgchomozygoteEarly adultN/A * 
increased neutrophil cell number2 supporting datasetsZfp260tm1b(NCOM)MfgcheterozygoteEarly adult1.98x10-5 
short tibia1 supporting datasetZfp260tm1b(NCOM)MfgcheterozygoteEarly adult1.84x10-9 
edema1 supporting datasetZfp260tm1b(NCOM)MfgchomozygoteE15.5N/A * 
decreased bone mineral density1 supporting datasetZfp260tm1b(NCOM)MfgcheterozygoteEarly adult3.02x10-5 
preweaning lethality, complete penetrance1 supporting datasetZfp260tm1b(NCOM)MfgchomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Zfp260tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Zfp260tm1a(NCOM)MfgcKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Zfp260tm1b(NCOM)MfgcReporter-tagged deletion allele (with selection cassette)mouse
Zfp260tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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