Genes Phenotypes

Gene: Gnpda1

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Name
glucosamine-6-phosphate deaminase 1
MGI ID
MGI:1347054
Synonyms
Gnpi glucose-6-phosphate isomerase oscillin Gnp1
Viability
Homozygous - Lethal
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (9) Measurements chart (223) All data table (636)
Expression & images (29) Disease models (0) Histopathology (3) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
embryonic growth retardation Gnpda1tm1b(KOMP)Mbp HET E9.5 0.00
abnormal embryo size Gnpda1tm1b(KOMP)Mbp HOM E9.5 0.00
embryonic lethality prior to organogenesis Gnpda1tm1b(KOMP)Mbp HOM E9.5 0.00
embryonic growth retardation Gnpda1tm1b(KOMP)Mbp HOM E9.5 0.00
abnormal embryo size Gnpda1tm1b(KOMP)Mbp HET E9.5 0.00
abnormal uterus morphology Gnpda1tm1b(KOMP)Mbp HET Early adult 0.00
small kidney Gnpda1tm1b(KOMP)Mbp HET Early adult 0.00
embryonic lethality prior to tooth bud stage Gnpda1tm1b(KOMP)Mbp HOM E12.5 0.00
preweaning lethality, complete penetrance Gnpda1tm1b(KOMP)Mbp HOM Early adult 0.00

Download data as:  TSV  XLS

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/61) N/A
Brain 4  (6/504) N/A
Central nervous system ganglion 2  (1/70) N/A
Ear 4  (1/504) N/A
Embryo 4  (1/505)  (2/4) N/A
Eye 4  (1/504)  (2/4) N/A
Foot 4  (1/504) N/A
Forebrain 4  (1/504) N/A
Forelimb 4  (1/504) N/A
Gut 2  (1/56) N/A
Hand 4  (1/503) N/A
Head 4  (5/504) N/A
Heart 4  (1/504)  (2/4) N/A
Hindbrain 4  (6/504) N/A
Hindlimb 4  (1/503) N/A
Liver 4  (1/504) N/A
Lung 4  (1/500) N/A
Mandibular process 4  (1/504) N/A
Maxillary process 4  (1/504) N/A
Midbrain 4  (1/504) N/A
Nose 2  (1/70) N/A
Oral cavity 4  (1/504) N/A
Skeleton 2  (1/70) N/A
Skin 4  (1/504) N/A
Spinal cord 2  (1/69) N/A
Tail 4  (1/504) N/A
Tail somite 4  (1/504) N/A
Trachea 2  (1/56) N/A
Urinary system 2  (1/56) N/A

 Associated Images

Combined SHIRPA and Dysmorphology
2 Images
Histopathology
5 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
15 Images
X-ray: XRay Images Hind Leg and Hip
15 Images
X-ray: XRay Images Whole Body Lateral Orientation
30 Images
X-ray: XRay Images Whole Body Dorso Ventral
15 Images
Eye Morphology: Images Slit Lamp
4 Images
Embryo LacZ: LacZ images wholemount
32 Images
Eye Morphology: Images Ophthalmoscopy
9 Images
Gross Pathology and Tissue Collection
6 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Thyroid - process of degenerative change Gnpda1tm1b(KOMP)Mbp HET Early adult
Epididymis - growth and differentiation defect Gnpda1tm1b(KOMP)Mbp HET Early adult
Testes - process of degenerative change Gnpda1tm1b(KOMP)Mbp HET Early adult

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Gnpda1tm1a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Gnpda1tm1b(KOMP)Mbp Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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