Gene: Plod3

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Name
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
MGI ID
MGI:1347008
Synonyms
lysyl hydroxylase 3 LH3
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal embryo size Plod3tm1.1(KOMP)Wtsi HOM E9.5 0.00
abnormal urinary bladder morphology Plod3tm1.1(KOMP)Wtsi HET Early adult 0.00
abnormal auditory brainstem response Plod3tm1.1(KOMP)Wtsi HET   Early adult 6.96×10-05
embryonic lethality prior to tooth bud stage Plod3tm1.1(KOMP)Wtsi HOM   E12.5 0.00
embryonic growth retardation Plod3tm1.1(KOMP)Wtsi HOM E9.5 0.00
preweaning lethality, complete penetrance Plod3tm1.1(KOMP)Wtsi HOM   Early adult 0.00
decreased grip strength Plod3tm1.1(KOMP)Wtsi HET Early adult 2.47×10-06
abnormal pericardium morphology Plod3tm1.1(KOMP)Wtsi HOM E9.5 0.00

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 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (1/64) N/A
2  (6/505)  (2/2) N/A
2  (1/73)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/506) Image Only N/A
2  (1/505)  (2/2) N/A
2  (1/505) N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/59) N/A
2  (1/505) N/A
2  (5/505) N/A
2  (1/505)  (2/2) N/A
2  (6/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/503) N/A
2  (1/503) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/505)  (2/2) N/A
2  (1/75) N/A
2  (1/503)  (2/2) N/A
2  (1/75) N/A
2  (1/505) N/A
2  (1/72)  (2/2) N/A
2  (1/505) N/A
2  (1/505)  (2/2) N/A
2  (1/59) N/A
2  (1/59)  (2/2) N/A

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
10 Images
Embryo LacZ: LacZ images wholemount
8 Images
Gross Morphology Embryo E9.5
6 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Plod3tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Plod3tm1.1(KOMP)Wtsi Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Plod3tm1(KOMP)Wtsi Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells

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