Not currently registered for phenotyping at IMPC
Phenotyping is currently not planned for a knockout strain of this gene.
Gene Summary
IMPC Data Collections
- No Body Weight Data
- No Embryo Imaging Data
- No Viability Data
Phenotyping is currently not planned for a knockout strain of this gene.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Lypla2.
There are 4 publications which use IMPC produced mice or data.
Title | Journal | IMPC Allele | PubMed ID |
---|---|---|---|
Hepatic palmitoyl-proteomes and acyl-protein thioesterase protein proximity networks link lipid modification and mitochondria. | Cell reports (November 2023) | Lypla2tm1c(KOMP)Mbp Lypla2tm1a(KOMP)Mbp | 37925639 |
Palmitoylation couples insulin hypersecretion with β cell failure in diabetes. | Cell metabolism (January 2023) | Lypla2tm1a(KOMP)Mbp | 36634673 |
Endothelial Palmitoylation Cycling Coordinates Vessel Remodeling in Peripheral Artery Disease. | Circulation research (April 2020) | Lypla2tm1a(KOMP)Mbp | 32233916 |
Temporal Profiling Establishes a Dynamic S-Palmitoylation Cycle. | ACS chemical biology (May 2018) | Lypla2tm1a(KOMP)Mbp Lypla2tm1b(KOMP)Mbp | 29733200 |
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
MGI Allele | Allele Type | Produced |
---|---|---|
Lypla2tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | Targeting vectors, ES Cells |
Lypla2tm1e(KOMP)Wtsi | Targeted, non-conditional allele | ES Cells |
Lypla2tm1e(KOMP)Mbp | Targeted, non-conditional allele | ES Cells |
Lypla2tm1a(KOMP)Mbp | KO first allele (reporter-tagged insertion with conditional potential) | Mice, Targeting vectors, ES Cells |
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