Gene: Map3k1

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Name
mitogen-activated protein kinase kinase kinase 1
MGI ID
MGI:1346872
Synonyms
MEKK1 Mekk
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased bone mineral density Map3k1tm1a(KOMP)Wtsi HET   Early adult 3.26×10-05
increased circulating cholesterol level Map3k1Gt(YTC001)Byg HET   Early adult 4.64×10-05
preweaning lethality, incomplete penetrance Map3k1tm1a(KOMP)Wtsi HOM   Early adult 0.00
decreased fasting circulating glucose level Map3k1tm1a(KOMP)Wtsi HET Early adult 1.22×10-08
increased bone mineral content Map3k1tm1a(KOMP)Wtsi HET Early adult 7.19×10-08
abnormal startle reflex Map3k1Gt(YTC001)Byg HET Early adult 5.41×10-05
decreased circulating fructosamine level Map3k1tm1a(KOMP)Wtsi HET Early adult 1.65×10-07
increased circulating HDL cholesterol level Map3k1Gt(YTC001)Byg HET   Early adult 2.32×10-06
abnormal retina morphology Map3k1tm1a(KOMP)Wtsi HET Early adult 4.58×10-05
increased lean body mass Map3k1tm1a(KOMP)Wtsi HET Early adult 1.43×10-05

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 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
14 Images
X-ray: XRay Images Whole Body Dorso Ventral
14 Images
X-ray: XRay Images Forepaw
12 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
13 Images
X-ray: XRay Images Skull Lateral Orientation
14 Images
Histopathology
4 Images
Legacy Phenotype Associated Images

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 Disease Models

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 Histopathology

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MGI Allele Allele Type Produced
Map3k1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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