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Genes Phenotypes

Gene: Mapk1

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Name
mitogen-activated protein kinase 1
MGI ID
MGI:1346858
Synonyms
p42mapk MAPK2 Erk2 Prkm1 9030612K14Rik
Viability
Homozygous - Lethal
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (1) Measurements chart (0) All data table (263)
Expression & images (45) Disease models (0) Order (4)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Mapk1tm1a(EUCOMM)Wtsi HOM   Early adult 0.00

Download data as:  TSV  XLS

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/590) N/A
Aorta 2 No  (1/590) N/A
Blood vessel 2 No N/A
Bone 2 No N/A
Brain 2 No  (3/590)  (2/2) N/A
Brainstem 2 No  (2/590) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (3/590) N/A
Cerebral cortex 2 No  (2/590) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (1/590) N/A
Hippocampus 2 No  (3/590) N/A
Hypothalamus 2 No  (2/590) N/A
Kidney 2 No  (20/590) N/A
Large intestine 2 No  (10/590) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/590) N/A
Lung 2 No  (1/590) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Esophagus 2 No N/A
Olfactory lobe 2 No  (2/590) N/A
Ovary 2 No  (1/590) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/590) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No  (1/590) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/590) N/A
Prostate gland 2 No  (12/590) N/A
Skeletal muscle tissue 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/590) N/A
Spinal cord 2 No  (2/590) N/A
Spleen 2 No  (2/590) N/A
Stomach 2 No  (13/590) N/A
Striatum 2 No  (3/590) N/A
Testis 2 No  (5/590) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (16/590) N/A
Trachea 2 No  (2/590) N/A
Uterus 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
LacZ Section Images
Mapk1tm1a(EUCOMM)Wtsi
brain, HET, Female, WTSI
Mapk1tm1a(EUCOMM)Wtsi
brain, HET, Female, WTSI
Mapk1tm1a(EUCOMM)Wtsi
brain, HET, Female, WTSI
Mapk1tm1a(EUCOMM)Wtsi
brain, HET, Female, WTSI
No Embryo expression data was found for this gene.

 Associated Images

Legacy Phenotype Associated Images
Mapk1tm1a(EUCOMM)Wtsi
forearm, HET, Female, WTSI
Mapk1tm1a(EUCOMM)Wtsi
body, HET, Male, WTSI
Mapk1tm1a(EUCOMM)Wtsi
head, HET, Male, WTSI
Mapk1tm1a(EUCOMM)Wtsi
forearm, HET, Male, WTSI
Mapk1tm1a(EUCOMM)Wtsi
HET, Male, WTSI

View all 46 images

Mapk1tm1a(EUCOMM)Wtsi
back skin, HET, Female, WTSI
Mapk1tm1a(EUCOMM)Wtsi
back skin, HET, Female, WTSI
Mapk1tm1a(EUCOMM)Wtsi
eye, abnormal placement of pupils, abnormal pupil morphology, HET, Female, WTSI

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Mapk1tm42428(L1L2_Bact_P) Targeting vectors
Mapk1tm42428(L1L2_Pgk_P) Targeting vectors
Mapk1tm42428(L1L2_Pgk_PM) Targeting vectors
Mapk1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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