Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
matrix metallopeptidase 17
Synonyms:
MT4-MMP,  membrane type-4 matrix metalloproteinase

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Mmp17 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Mmp17 by phenotypic similarity.

Disease Similarity of
phenotypes
Matching phenotypes Source
Senior-Loken Syndrome 1
Nephronophthisis, Polyuria, Stage 5 chronic kidney disease, Polydipsia OMIM:266900
Adenine Phosphoribosyltransferase Deficiency
Macroscopic hematuria, Urinary hesitancy, Urinary retention, Dysuria, Nephrolithiasis, Stage 5 ch... ORPHA:976
Nephronophthisis 7
Renal tubular atrophy, Nephronophthisis, Stage 5 chronic kidney disease OMIM:611498
Senior-Loken Syndrome 4
Nephronophthisis, Polyuria, Stage 5 chronic kidney disease, Polydipsia OMIM:606996
Renal Glucosuria
Polydipsia, Polyphagia, Enuresis nocturna, Glycosuria, Polyuria OMIM:233100
Nephronophthisis 20
Renal insufficiency, Nephronophthisis, Renal cyst, Stage 5 chronic kidney disease OMIM:617271
Senior-Loken Syndrome 5
Nephronophthisis, Stage 5 chronic kidney disease OMIM:609254
Nephronophthisis 12
Nephronophthisis, Stage 5 chronic kidney disease OMIM:613820
Nephronophthisis 4
Renal tubular atrophy, Polydipsia, Nephronophthisis, Tubulointerstitial fibrosis, Renal corticome... OMIM:606966
Nephronophthisis 1
Renal tubular atrophy, Polydipsia, Nephronophthisis, Tubulointerstitial fibrosis, Renal corticome... OMIM:256100
Nephronophthisis 3
Renal tubular atrophy, Polydipsia, Nephronophthisis, Tubulointerstitial fibrosis, Renal corticome... OMIM:604387
Senior-Loken Syndrome 3
Polydipsia, Nephronophthisis, Renal corticomedullary cysts, Stage 5 chronic kidney disease, Enure... OMIM:606995
Nephronophthisis-Like Nephropathy 2
Polydipsia, Stage 5 chronic kidney disease, Polyuria, Periglomerular fibrosis, Renal insufficienc... OMIM:619468
Noduli Cutanei, Multiple, With Urinary Tract Abnormalities
Hydronephrosis, Duplicated collecting system OMIM:163850
Renal Hypoplasia
Urethral valve, Hydronephrosis, Abnormality of the ureter, Polydipsia, Pelvic kidney, Glomerulome... ORPHA:93101
Diabetes Insipidus, Neurohypophyseal, X-Linked
Hydronephrosis, Polyuria, Polydipsia OMIM:304900
Nephronophthisis 9
Nephronophthisis, Renal cortical microcysts, Stage 5 chronic kidney disease OMIM:613824
Type 1 Diabetes Mellitus
Polyuria, Polyphagia, Polydipsia OMIM:222100
Senior-Loken Syndrome 7
Nephronophthisis OMIM:613615
Ochoa Syndrome
Hydronephrosis, Polydipsia, Recurrent urinary tract infections, Urinary incontinence, Vesicourete... ORPHA:2704
Nephronophthisis 11
Renal tubular atrophy, Polydipsia, Nephronophthisis, Renal corticomedullary cysts, Stage 5 chroni... OMIM:613550
Interstitial Nephritis, Karyomegalic
Tubulointerstitial nephritis, Nephronophthisis, Hematuria, Stage 5 chronic kidney disease, Glycos... OMIM:614817
Acquired Central Diabetes Insipidus
Pollakisuria, Polydipsia ORPHA:95626
Genetic Recurrent Myoglobinuria
Exercise-induced myoglobinuria, Dark urine, Acute kidney injury, Oliguria, Renal insufficiency, R... ORPHA:99845
Hemolytic Uremic Syndrome, Atypical, Susceptibility To, 3
Anuria, Hematuria, Hemolytic-uremic syndrome, Acute kidney injury, Proteinuria OMIM:612923
Hemolytic Uremic Syndrome, Atypical, Susceptibility To, 2
Anuria, Hematuria, Hemolytic-uremic syndrome, Acute kidney injury, Proteinuria OMIM:612922
Hemolytic Uremic Syndrome, Atypical, Susceptibility To, 5
Anuria, Hematuria, Hemolytic-uremic syndrome, Acute kidney injury, Proteinuria OMIM:612925
Hemolytic Uremic Syndrome, Atypical, Susceptibility To, 4
Anuria, Hematuria, Hemolytic-uremic syndrome, Acute kidney injury, Proteinuria OMIM:612924
Hemolytic Uremic Syndrome, Atypical, Susceptibility To, 6
Anuria, Hematuria, Hemolytic-uremic syndrome, Acute kidney injury, Proteinuria OMIM:612926
Hypercalcemia, Infantile, 2
Nephrocalcinosis, Renal phosphate wasting, Medullary nephrocalcinosis, Hypercalciuria, Polyuria OMIM:616963
Renal Tubular Acidosis, Distal, With Nephrocalcinosis, Short Stature, Mental Retardation, And Distinctive Facies
Renal cortical hyperechogenicity, Renal hypoplasia, Medullary nephrocalcinosis, Reduced renal cor... OMIM:611555
Coach Syndrome 3
Renal tubular atrophy, Renal interstitial inflammation, Renal interstitial fibrosis, Nephronophth... OMIM:619113
Nephronophthisis 18
Renal tubular atrophy, Tubulointerstitial nephritis, Nephronophthisis, Stage 5 chronic kidney dis... OMIM:615862
Diffuse Cutaneous Systemic Sclerosis
Oliguria, Renal insufficiency, Dysphagia ORPHA:220393
Nephronophthisis 14
Nephronophthisis, Polycystic kidney dysplasia OMIM:614844
Urofacial Syndrome 2
Hydronephrosis, Urinary urgency, Recurrent urinary tract infections, Vesicoureteral reflux, Enure... OMIM:615112
Teratoma, Pineal
Polyuria, Polydipsia OMIM:273120
Joubert Syndrome 4
Nephronophthisis, Abnormal renal medulla morphology, Renal insufficiency OMIM:609583
Lassa Fever
Oliguria, Dysphagia ORPHA:99824
Systemic Capillary Leak Syndrome
Renal insufficiency, Oliguria, Abnormal renal tubule morphology ORPHA:188
Ocular Motor Apraxia
Nephronophthisis OMIM:257550
Renal Hypodysplasia/Aplasia 3
Horseshoe kidney, Hydronephrosis, Renal agenesis, Renal dysplasia, Multicystic kidney dysplasia, ... OMIM:617805
Congenital Primary Megaureter
Hydronephrosis, Abnormal penis morphology, Congenital megaureter, Nephrolithiasis, Recurrent urin... ORPHA:617
Hypomagnesemia 3, Renal
Polydipsia, Nephrocalcinosis, Renal tubular acidosis, Hematuria, Renal calcium wasting, Nephrolit... OMIM:248250
Renal Tubular Dysgenesis
Abnormality of the urinary system, Renotubular dysgenesis, Anuria OMIM:267430
Renal Caliceal Diverticuli-Deafness Syndrome
Hydronephrosis, Abnormality of the urinary system, Abnormality of the upper urinary tract, Hydrou... ORPHA:2838
Senior-Loken Syndrome
Chronic kidney disease, Nephronophthisis, Stage 5 chronic kidney disease ORPHA:3156
Congenital Megacalycosis
Hydronephrosis, Tubulointerstitial nephritis, Dilatation of renal calices, Abnormal renal physiol... ORPHA:93109
Nephronophthisis 13
Renal hypoplasia, Mild proteinuria, Nephronophthisis, Stage 5 chronic kidney disease OMIM:614377
Oligomeganephronia
Bilateral renal hypoplasia, Renal tubular atrophy, Abnormal nephron morphology, Polydipsia, Abnor... ORPHA:2260
Nephronophthisis 16
Nephronophthisis, Polycystic kidney dysplasia, Renal insufficiency, Enlarged kidney OMIM:615382
Acute Monoblastic/Monocytic Leukemia
Oliguria ORPHA:514
Microscopic Polyangiitis
Glomerulopathy, Hematuria, Renal insufficiency, Oliguria ORPHA:727
Congenital Anomalies Of Kidney And Urinary Tract 3
Ectopic kidney, Hydronephrosis, Renal cyst, Vesicoureteral reflux OMIM:618270
Congenital Anomalies Of Kidney And Urinary Tract 2
Cystic renal dysplasia, Renal hypoplasia, Hydronephrosis, Renal sarcoma, Nephrotic syndrome, Rena... OMIM:143400
Carnitine-Acylcarnitine Translocase Deficiency
Oliguria, Dicarboxylic aciduria ORPHA:159
Nephronophthisis 15
Nephronophthisis OMIM:614845
Hyperaldosteronism, Familial, Type Iii
Hypercalciuria, Polyuria, Polydipsia OMIM:613677
Rhyns Syndrome
Nephronophthisis, Multicystic kidney dysplasia ORPHA:140976
Medullary cystic kidney disease 2
Renal tubular atrophy, Tubulointerstitial nephritis, Multiple small medullary renal cysts, Renal ... OMIM:603860
Autosomal Recessive Polycystic Kidney Disease
Polydipsia, Stage 5 chronic kidney disease, Recurrent urinary tract infections, Acute kidney inju... ORPHA:731
Nephronophthisis 2
Chronic tubulointerstitial nephritis, Nephronophthisis, Stage 5 chronic kidney disease, Absence o... OMIM:602088
Joubert Syndrome 16
Nephronophthisis, Renal cyst OMIM:614465
Duplication Of Urethra
Hypospadias, Bladder duplication, Chordee, Hypertrophy of the urinary bladder, Anuria, Dysuria, C... ORPHA:237
Hemorrhagic Fever-Renal Syndrome
Decreased urine output, Tubulointerstitial nephritis, Anuria, Decreased glomerular filtration rat... ORPHA:340
Lujo Hemorrhagic Fever
Microscopic hematuria, Renal insufficiency, Dysphagia, Oliguria ORPHA:319213
Diabetes Insipidus, Nephrogenic, 2, Autosomal
Megacystis, Polyuria, Polydipsia OMIM:125800
Diabetes Insipidus, Nephrogenic, 1, X-Linked
Megacystis, Polyuria, Polydipsia OMIM:304800
Joubert Syndrome 15
Nephronophthisis, Micropenis OMIM:614464
East Syndrome
Renal salt wasting, Renal sodium wasting, Polydipsia, Salt craving, Abnormal urinary electrolyte ... ORPHA:199343
Nephrogenic Diabetes Insipidus
Polydipsia, Enuresis nocturna, Functional abnormality of the bladder, Hydroureter, Renal insuffic... ORPHA:223
Nephronophthisis 19
Nephronophthisis, Stage 5 chronic kidney disease OMIM:616217
Jeune Syndrome
Nephronophthisis, Renal insufficiency, Nephropathy ORPHA:474
Aneurysm Of Sinus Of Valsalva
Oliguria ORPHA:1054
Seizures, Sensorineural Deafness, Ataxia, Mental Retardation, And Electrolyte Imbalance
Renal salt wasting, Renal sodium wasting, Polydipsia, Salt craving, Hypocalciuria, Renal potassiu... OMIM:612780
Sepsis In Premature Infants
Oliguria, Reversible renal failure ORPHA:90051
Colchicine Poisoning
Oliguria, Renal insufficiency ORPHA:31824
Central Diabetes Insipidus
Nocturia, Polydipsia ORPHA:178029
Apparent Mineralocorticoid Excess
Abnormal urine sodium concentration, Renal insufficiency, Polydipsia, Nephrocalcinosis ORPHA:320
Helix Syndrome
Polydipsia, Nephrolithiasis, Hypocalciuria, Polyuria, Renal insufficiency OMIM:617671
Hypercalcemia, Infantile, 1
Hypercalciuria, Polyuria, Nephrolithiasis, Nephrocalcinosis OMIM:143880
Vesicoureteral Reflux 3
Hydronephrosis, Hydroureter, Vesicoureteral reflux OMIM:613674
Idiopathic Steroid-Resistant Nephrotic Syndrome
Focal segmental glomerulosclerosis, Foamy urine, Minimal change glomerulonephritis, Abnormal glom... ORPHA:567548
Senior-Loken Syndrome 9
Nephronophthisis, Tubulointerstitial nephritis, Stage 5 chronic kidney disease OMIM:616629
Hinman Syndrome
Hydronephrosis, Recurrent urinary tract infections, Vesicoureteral reflux, Enuresis, Renal insuff... ORPHA:84085
Bardet-Biedl Syndrome 9
Polydipsia, Renal insufficiency, Polyphagia OMIM:615986
Bardet-Biedl Syndrome 17
Polydipsia, Renal cyst, Stage 5 chronic kidney disease, Micropenis, Polyuria OMIM:615994
Hypomagnesemia, Seizures, And Mental Retardation 2
Renal potassium wasting, Polyuria, Renal magnesium wasting OMIM:618314
Infection-Related Hemolytic Uremic Syndrome
Decreased urine output, Anuria, Acute kidney injury, Oliguria, Nephrotic range proteinuria ORPHA:544482
Senior-Boichis Syndrome
Renal hypoplasia, Abnormal renal insterstitial morphology, Thickening of the tubular basement mem... ORPHA:84081
Short-Rib Thoracic Dysplasia 9 With Or Without Polydactyly
Renal dysplasia, Nephronophthisis, Renal cyst, Stage 5 chronic kidney disease, Nephropathy OMIM:266920
Nephronophthisis-Like Nephropathy 1
Renal tubular atrophy, Nephronophthisis, Renal corticomedullary cysts, Stage 5 chronic kidney dis... OMIM:613159
Hemolytic Uremic Syndrome, Atypical, Susceptibility To, 1
Anuria, Acute kidney injury, Hemolytic-uremic syndrome OMIM:235400
Cystinosis
Renal tubular dysfunction, Polydipsia, Nephropathy, Aminoaciduria, Proteinuria, Renal insufficiency ORPHA:213
Tubulointerstitial Kidney Disease, Autosomal Dominant, 2
Renal tubular atrophy, Renal hypoplasia, Tubulointerstitial nephritis, Renal cortical atrophy, De... OMIM:174000
Cardiogenic Shock
Oliguria ORPHA:97292
Renal Dysplasia
Abnormal renal calyx morphology, Chronic kidney disease, Abnormal nephron morphology, Vesicovagin... ORPHA:93108
Primary Hyperoxaluria Type 3
Calcium oxalate nephrolithiasis, Abnormality of urine homeostasis, Nephrocalcinosis, Hematuria, H... ORPHA:93600
Bartter Syndrome, Type 4A, Neonatal, With Sensorineural Deafness
Increased urinary potassium, Decreased glomerular filtration rate, Tubulointerstitial fibrosis, R... OMIM:602522
Hyperphosphatemia, Polyuria, And Seizures
Polyuria OMIM:239350
Distal Renal Tubular Acidosis
Hyperphosphaturia, Aminoaciduria, Polydipsia, Nephrocalcinosis, Proximal tubulopathy, Decreased g... ORPHA:18
Rhyns Syndrome
Chronic kidney disease, Nephronophthisis, Renal insufficiency OMIM:602152
Hereditary Central Diabetes Insipidus
Polydipsia ORPHA:30925
Hyperparathyroidism, Neonatal Severe
Hyperphosphaturia, Aminoaciduria, Polydipsia, Hypercalciuria, Polyuria OMIM:239200
Proximal Renal Tubular Acidosis
Hyperphosphaturia, Aminoaciduria, Bicarbonate-wasting renal tubular acidosis, Nephrocalcinosis, P... ORPHA:47159
Coenzyme Q10 Deficiency, Primary, 8
Renal dysplasia, Abnormal renal corticomedullary differentiation OMIM:616733
Amelogenesis Imperfecta, Type Ig
Nephrocalcinosis, Impaired renal concentrating ability, Enuresis, Polyuria, Renal insufficiency OMIM:204690
Megacystis-Microcolon-Intestinal Hypoperistalsis Syndrome 2
Renal cortical hyperechogenicity, Anuria, Megacystis, Fetal megacystis, Pyelonephritis OMIM:619351
Joubert Syndrome 7
Nephronophthisis, Renal cyst OMIM:611560
Car T Cell Therapy-Associated Cytokine Release Syndrome
Acute kidney injury, Decreased urine output ORPHA:542323
Xanthinuria, Type I
Xanthinuria, Hydronephrosis, Pyelonephritis, Xanthine nephrolithiasis OMIM:278300
Joubert Syndrome 3
Nephronophthisis, Stage 5 chronic kidney disease OMIM:608629
Familial Hyperaldosteronism Type Iii
Hypercalciuria, Polydipsia ORPHA:251274
Bartter Syndrome, Type 5, Antenatal, Transient
Medullary nephrocalcinosis, Polyuria, Hypercalciuria OMIM:300971
Juvenile Nephropathic Cystinosis
Renal Fanconi syndrome, Polydipsia, Proximal tubulopathy, Stage 5 chronic kidney disease, Glycosu... ORPHA:411634
Bartter Syndrome, Type 3
Renal salt wasting, Increased urinary potassium, Hypocalciuria, Renal potassium wasting, Hyperchl... OMIM:607364
Aapoaiv Amyloidosis
Abnormal renal medulla morphology, Glomerular sclerosis, Renal interstitial amyloid deposits, Chr... ORPHA:439232
Hyperuricemia, Pulmonary Hypertension, Renal Failure, And Alkalosis Syndrome
Chronic kidney disease, Proteinuria, Hyperechogenic kidneys, Renal salt wasting, Polyuria OMIM:613845
Gitelman Syndrome
Polydipsia, Salt craving, Hypocalciuria, Renal potassium wasting, Enuresis, Polyuria, Nocturia, R... OMIM:263800
Senior-Loken Syndrome 8
Nephronophthisis OMIM:616307
Bartter Syndrome, Type 4B, Neonatal, With Sensorineural Deafness
Increased urinary potassium, Decreased glomerular filtration rate, Renal insufficiency, Hyperchlo... OMIM:613090
Hnf1B-Related Autosomal Dominant Tubulointerstitial Kidney Disease
Hypospadias, Horseshoe kidney, Renal Fanconi syndrome, Renal agenesis, Polydipsia, Renal cell car... ORPHA:93111
Posterior Urethral Valve
Hydronephrosis, Urinary retention, Urethral stenosis, Congenital posterior urethral valve, Unilat... ORPHA:93110
Infantile Nephropathic Cystinosis
Hyperphosphaturia, Renal Fanconi syndrome, Renal tubular dysfunction, Polydipsia, Abnormal tubulo... ORPHA:411629
Primary Unilateral Adrenal Hyperplasia
Polydipsia, Increased urinary potassium ORPHA:231580
Exercise-Induced Malignant Hyperthermia
Acute kidney injury, Oliguria ORPHA:466650
Cholera
Abnormality of renal excretion, Acute kidney injury, Decreased urine output ORPHA:173
Short-Rib Thoracic Dysplasia 10 With Or Without Polydactyly
Chronic kidney disease, Nephronophthisis OMIM:615630
Ethylene Glycol Poisoning
Renal tubular dysfunction, Decreased urine output, Hematuria, Renal tubular epithelial necrosis, ... ORPHA:31826
Polycystic Kidney Disease 4 With Or Without Polycystic Liver Disease
Tubulointerstitial fibrosis, Renal cyst, Polycystic kidney dysplasia, Absence of renal corticomed... OMIM:263200
Shiga Toxin-Associated Hemolytic Uremic Syndrome
Anuria, Acute kidney injury, Hemoglobinuria ORPHA:90038
Coach Syndrome 1
Nephronophthisis, Multiple small medullary renal cysts, Renal cyst, Stage 5 chronic kidney diseas... OMIM:216360
Joubert Syndrome 6
Nephronophthisis, Stage 5 chronic kidney disease OMIM:610688
Primary Hyperaldosteronism-Seizures-Neurological Abnormalities Syndrome
Nephrolithiasis, Polydipsia ORPHA:369929
Familial Cold Urticaria
Polydipsia ORPHA:47045
Bartter Syndrome, Type 2, Antenatal
Polydipsia, Nephrocalcinosis, Increased urinary potassium, Hyperprostaglandinuria, Hyperchloridur... OMIM:241200
Hyperparathyroidism-Jaw Tumor Syndrome
Dysphagia, Polydipsia, Nephrocalcinosis, Renal cyst, Nephrolithiasis, Renal hamartoma, Renal insu... ORPHA:99880
Brain-Lung-Thyroid Syndrome
Hypospadias, Abnormal drinking behavior, Megacystis, Abnormal eating behavior, Vesicoureteral reflux ORPHA:209905
Odontochondrodysplasia 1
Nephronophthisis, Polycystic kidney dysplasia OMIM:184260
Pyruvate Dehydrogenase E1-Alpha Deficiency
Abnormality of medullary pyramid morphology ORPHA:79243
Parathyroid Carcinoma
Dysphagia, Polydipsia, Nephrocalcinosis, Renal cyst, Nephrolithiasis, Renal hamartoma, Renal insu... ORPHA:143
Cystinosis, Nephropathic
Renal Fanconi syndrome, Dysphagia, Generalized aminoaciduria, Polydipsia, Nephrolithiasis, Glycos... OMIM:219800
Renal Tubulopathy, Diabetes Mellitus, And Cerebellar Ataxia
Proximal tubulopathy, Polyuria OMIM:560000
Hypocalciuric Hypercalcemia, Familial, Type Iii
Multiple small medullary renal cysts, Parathormone-independent increased renal tubular calcium re... OMIM:600740
Congenital Anomalies Of Kidney And Urinary Tract Syndrome With Or Without Hearing Loss, Abnormal Ears, Or Developmental Delay
Horseshoe kidney, Renal hypoplasia, Renal agenesis, Renal dysplasia, Bifid ureter, Decreased numb... OMIM:617641
Arima Syndrome
Renal tubular atrophy, Nephronophthisis, Tubulointerstitial fibrosis, Renal corticomedullary cyst... OMIM:243910
Familial Hyperaldosteronism Type I
Polydipsia ORPHA:403
Wolfram Syndrome
Polydipsia, Abnormality of the urinary system, Dysuria, Recurrent urinary tract infections, Nephr... ORPHA:3463
Bartter Syndrome, Type 1, Antenatal
Nephrocalcinosis, Increased urinary potassium, Hyperprostaglandinuria, Hyperchloriduria, Renal po... OMIM:601678
Joubert Syndrome 5
Renal cortical cysts, Nephronophthisis, Impaired renal concentrating ability, Stage 5 chronic kid... OMIM:610188
Tumoral Calcinosis, Hyperphosphatemic, Familial, 1
Increased renal tubular phosphate reabsorption, Decreased renal tubular phosphate excretion, Neph... OMIM:211900
Erdheim-Chester Disease
Hydronephrosis, Dysuria, Renal insufficiency, Polydipsia ORPHA:35687
Septo-Optic Dysplasia Spectrum
Hypoplasia of penis, Polydipsia ORPHA:3157
Atresia Of Urethra
Patent urachus, Hydronephrosis, Renal dysplasia, Megacystis, Bladder fistula, Recurrent urinary t... ORPHA:105
Joubert Syndrome 2
Abnormal renal physiology, Renal cyst, Nephronophthisis OMIM:608091
Toxic Epidermal Necrolysis
Dysphagia, Polydipsia, Dysuria, Abnormality of the urethra, Renal insufficiency ORPHA:537
Yellow Fever
Anuria, Acute kidney injury, Renal insufficiency ORPHA:99829
Panhypophysitis
Hyposthenuria, Polydipsia ORPHA:95513
Ventriculomegaly With Cystic Kidney Disease
Renal insufficiency, Renal corticomedullary cysts OMIM:219730
Gitelman Syndrome
Renal Fanconi syndrome, Focal segmental glomerulosclerosis, Tubulointerstitial nephritis, Polydip... ORPHA:358
Cranioectodermal Dysplasia 3
Nephronophthisis, Stage 5 chronic kidney disease OMIM:614099
Pediatric-Onset Graves Disease
Polydipsia, Polyphagia ORPHA:525731
Short Rib-Polydactyly Syndrome
Hypospadias, Nephronophthisis, Urogenital sinus anomaly, Polycystic kidney dysplasia, Multiple gl... ORPHA:1505
Degcags Syndrome
Hypospadias, Bilateral renal hypoplasia, Renal hypoplasia, Chordee, Oral-pharyngeal dysphagia, Ch... OMIM:619488
Rabson-Mendenhall Syndrome
Polydipsia, Long penis, Nephrocalcinosis ORPHA:769
Osteopetrosis, Autosomal Recessive 5
Absence of renal corticomedullary differentiation OMIM:259720
Whipple Disease
Polydipsia ORPHA:3452
Diarrhea 10, Protein-Losing Enteropathy Type
Renal dysplasia, Polyuria OMIM:618183
Neuromuscular Oculoauditory Syndrome
Multiple renal cysts, Reduced renal corticomedullary differentiation OMIM:618733
Pituitary Dermoid And Epidermoid Cysts
Polydipsia ORPHA:91351
Cornelia De Lange Syndrome 1
Hypospadias, Renal hypoplasia, Renal cyst, Reduced renal corticomedullary differentiation, Abnorm... OMIM:122470
Alagille Syndrome 1
Renal hypoplasia, Focal segmental glomerulosclerosis, Renal tubular acidosis, Renal dysplasia, Mu... OMIM:118450
Rapid-Onset Childhood Obesity-Hypothalamic Dysfunction-Hypoventilation-Autonomic Dysregulation Syndrome
Enuresis, Polydipsia, Polyphagia ORPHA:293987
Autosomal Recessive Hypophosphatemic Rickets
Abnormality of renal excretion, Renal phosphate wasting, Hyperphosphaturia ORPHA:289176
Zttk Syndrome
Horseshoe kidney, Polyuria, Unilateral renal agenesis OMIM:617140

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Mmp17

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Mmp17.

No publications found that use IMPC mice or data for Mmp17.

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MGI Allele Allele Type Produced
Mmp17tm172129(L1L2_Bact_P) KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors

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