Bves | blood vessel epicardial substance

GeneMGI:1346013Synonyms: Popdc1, popeye 1

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Integument Adipose tissue Behavior/neurological Skeleton Mortality/aging

14 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

2Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



improved glucose tolerance	1 supporting dataset	Bves^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.21x10^-6
decreased locomotor activity	4 supporting datasets	Bves^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	5.81x10^-6
abnormal skin morphology	1 supporting dataset	Bves^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
increased bone mineral content	1 supporting dataset	Bves^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.2x10^-15
decreased total body fat amount	1 supporting dataset	Bves^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	8.24x10^-5
increased grip strength	1 supporting dataset	Bves^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.41x10^-5
abnormal vocalization	1 supporting dataset	Bves^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.11x10^-5
preweaning lethality, incomplete penetrance	1 supporting dataset	Bves^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Bves.

Associated images

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Histopathology

There is no histopathology data found for Bves.

IMPC related publications

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External links

No external links available for Bves.

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*Bves^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Bves^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Bves^{tm92176(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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