Sufu | SUFU negative regulator of hedgehog signaling
Physiological systems
20 / 24 physiological systems tested
13 Significantly impacted by the knock-out
Vision/eye Nervous system Liver/biliary system Behavior/neurological Mortality/aging Integument Limbs/digits/tail Immune system Adipose tissue Digestive/alimentary Embryo Cardiovascular system Growth/size/body region
7 No significant impact
4 Not tested
Gene metrics:20Significant phenotypes
11Associated diseases
Expression examined in:41Adult tissues
30Embryo tissues
Human diseases caused by Sufu mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
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