Sufu | SUFU negative regulator of hedgehog signaling
Physiological systems
20 / 24 physiological systems tested
13 Significantly impacted by the knock-out
Immune system Integument Adipose tissue Embryo Growth/size/body region Digestive/alimentary Nervous system Vision/eye Liver/biliary system Limbs/digits/tail Behavior/neurological Mortality/aging Cardiovascular system
7 No significant impact
4 Not tested
Gene metrics:20Significant phenotypes
11Associated diseases
Expression examined in:41Adult tissues
30Embryo tissues
Human diseases caused by Sufu mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
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