Scn11a | sodium channel, voltage-gated, type XI, alpha

GeneMGI:1345149Synonyms: NSS2, NaN, +2 more

Physiological systems

18 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Growth/size/body region

17 No significant impact

6 Not tested

Gene metrics:1Significant phenotypes
8Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased lean body mass1 supporting datasetScn11aem1(IMPC)HhomozygoteEarly adult1.76x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Scn11aem1(IMPC)HExon Deletionmouse
Scn11aem2(IMPC)HExon Deletionmouse
Scn11atm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Scn11atm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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