Aloxe3 | arachidonate lipoxygenase 3
Physiological systems
22 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Immune system Embryo Growth/size/body region Vision/eye Hematopoietic system Mortality/aging Cardiovascular system
15 No significant impact
2 Not tested
Data collections
Gene metrics:10Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
preweaning lethality, complete penetrance | 3 supporting datasets | Aloxe3em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
abnormal lymph node morphology | 1 supporting dataset | Aloxe3em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
microphthalmia | 1 supporting dataset | Aloxe3em1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
hemorrhage | 1 supporting dataset | Aloxe3em1(IMPC)Mbp | heterozygote | E15.5 | N/A * | ||
embryonic growth retardation | 1 supporting dataset | Aloxe3em1(IMPC)Mbp | heterozygote | E15.5 | N/A * | ||
abnormal placenta morphology | 1 supporting dataset | Aloxe3em1(IMPC)Mbp | heterozygote | E15.5 | N/A * | ||
enlarged lymph nodes | 1 supporting dataset | Aloxe3em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
abnormal blood vessel morphology | 1 supporting dataset | Aloxe3em1(IMPC)Mbp | heterozygote | E15.5 | N/A * | ||
embryonic growth retardation | 1 supporting dataset | Aloxe3em1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
small spleen | 1 supporting dataset | Aloxe3em1(IMPC)Mbp | heterozygote | Early adult | N/A * |
| | | | | | | | | |
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Aloxe3.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
Aloxe3em1(IMPC)Mbp | Exon Deletion | | mouse |
Aloxe3tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Aloxe3tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
Aloxe3tm299258(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
Aloxe3tm2a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Aloxe3tm2e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |