Esyt1 | extended synaptotagmin-like protein 1

GeneMGI:1344426Synonyms: vp115, Fam62a, +1 more

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Growth/size/body region Vision/eye Behavior/neurological Skeleton Craniofacial

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal tooth morphology2 supporting datasetsEsyt1em1(IMPC)HmguhomozygoteEarly adult1.28x10-14 
abnormal gait1 supporting datasetEsyt1em1(IMPC)HmguhomozygoteEarly adult2x10-8 
sclerocornea1 supporting datasetEsyt1em1(IMPC)HmguhomozygoteEarly adult5.26x10-6 
abnormal iris transillumination1 supporting datasetEsyt1em1(IMPC)HmguhomozygoteEarly adult6.8x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Esyt1em1(IMPC)HmguExon Deletionmouse
Esyt1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Esyt1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Esyt1tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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