Gene: Arih2

Name
ariadne RBR E3 ubiquitin protein ligase 2
MGI ID
MGI:1344361
Synonyms
TRIAD1
Viability
Homozygous - Lethal
Other links
View data by physiological system
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
embryonic growth retardation Arih2tm1.1(KOMP)Vlcg HET embryonic day 9.5 0.00
abnormal skin morphology Arih2tm1.1(KOMP)Vlcg HET postnatal 0.00
abnormal seminal vesicle morphology Arih2tm1.1(KOMP)Vlcg HET postnatal 0.00
abnormal kidney morphology Arih2tm1.1(KOMP)Vlcg HET postnatal 0.00
decreased blood urea nitrogen level Arih2tm1.1(KOMP)Vlcg HET postnatal 2.33×10-07
abnormal bone structure Arih2tm1.1(KOMP)Vlcg HET postnatal 2.50×10-05
abnormal heart morphology Arih2tm1.1(KOMP)Vlcg HET postnatal 0.00
prolonged PR interval Arih2tm1.1(KOMP)Vlcg HET postnatal 7.89×10-05
embryonic growth retardation Arih2tm1.1(KOMP)Vlcg HOM embryonic day 9.5 0.00
decreased circulating triglyceride level Arih2tm1.1(KOMP)Vlcg HET postnatal 1.28×10-07
embryonic lethality prior to tooth bud stage Arih2tm1.1(KOMP)Vlcg HOM embryonic day 12.5 0.00
decreased circulating insulin level Arih2tm1.1(KOMP)Vlcg HET postnatal 2.33×10-08
enlarged heart Arih2tm1.1(KOMP)Vlcg HET postnatal 0.00
thick skin Arih2tm1.1(KOMP)Vlcg HET postnatal 0.00
abnormal embryo size Arih2tm1.1(KOMP)Vlcg HOM embryonic day 9.5 0.00
abnormal embryo size Arih2tm1.1(KOMP)Vlcg HET embryonic day 9.5 0.00
preweaning lethality, complete penetrance Arih2tm1.1(KOMP)Vlcg HOM n/a 0.00
cystolithiasis Arih2tm1.1(KOMP)Vlcg HET postnatal 0.00
abnormal urinary bladder morphology Arih2tm1.1(KOMP)Vlcg HET postnatal 0.00
decreased prepulse inhibition Arih2tm1.1(KOMP)Vlcg HET postnatal 1.61×10-07
polycystic kidney Arih2tm1.1(KOMP)Vlcg HET postnatal 0.00
decreased startle reflex Arih2tm1.1(KOMP)Vlcg HET postnatal 1.55×10-06

Download data as:  TSV  XLS

Filtered by: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2) N/A
Aorta 2 No  (2/2) N/A
Blood 2 No  (2/2) N/A
Bone marrow 2 No  (2/2) N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No  (2/2) N/A
Cartilage tissue 2 No N/A
Cecum 2 No  (12/383)  (2/2) N/A
Cerebellum 2 No  (2/2) N/A
Cerebral cortex 2 No N/A
Chest bone 2 No N/A
Colon 2 No  (12/127)  (2/2) N/A
Diaphragm 2 No  (2/2) N/A
Duodenum 2 No  (2/127)  (2/2) N/A
Epididymis 2 No  (18/134)  (1/2) N/A
Esophagus 2 No  (7/415)  (2/2) N/A
Eye 2 No  (2/2) N/A
Gall bladder 2 No N/A
Gonadal fat pad 2 No  (2/2) N/A
Harderian gland 2 No  (2/2) N/A
Heart 2 No N/A
Hindlimb 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Ileum 2 No  (14/127)  (2/2) N/A
Jejunum 2 No  (6/127) N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No  (2/2) N/A
Lower urinary tract 2 No N/A
Lung 2 No  (2/2) N/A
Lymph node 2 No N/A
Mammary gland 2 No  (1/2) N/A
Mesenteric adipose tissue 2 No  (2/2) N/A
Mesenteric lymph node 2 No  (2/2) N/A
Midbrain 2 No  (2/2) N/A
Olfactory lobe 2 No  (1/2) N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584)  (2/2) N/A
Parathyroid gland 2 No  (1/2) N/A
Parotid gland 2 No  (2/2) N/A
Penis 2 No  (1/2) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/2) N/A
Prostate gland 2 No  (12/584)  (1/2) N/A
Quadriceps 2 No  (2/2) N/A
Sciatic nerve 2 No  (2/2) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584)  (2/2) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Stomach pyloric region 2 No N/A
Striatum 2 No N/A
Sublingual gland 2 No  (2/2) N/A
Submandibular gland 2 No  (2/132)  (2/2) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No  (2/2) N/A
Thyroid gland 2 No  (15/584)  (2/2) N/A
Tongue 2 No  (5/127)  (2/2) N/A
Trachea 2 No  (2/2) N/A
Trigeminal V nerve 2 No  (2/2) N/A
Urinary bladder 2 No  (2/2) N/A
Uterus 2 No  (1/2) N/A
Vagina 2 No N/A
Vas deferens 2 No  (15/388)  (1/2) N/A
Vascular system 2 No N/A
Vesicular gland 2 No  (1/2) N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/51)  (2/2) N/A
Brain 8  (6/485)  (2/8) N/A
Central nervous system ganglion 2  (1/51)  (2/2) N/A
Ear 8  (1/485)  (2/8) N/A
Embryo 8  (1/485)  (2/8) N/A
Eye 8  (1/485)  (2/8) N/A
Foot 8  (1/485)  (2/8) N/A
Forebrain 8  (1/485)  (2/8) N/A
Forelimb 8  (1/485)  (2/8) N/A
Gut 2  (1/50)  (2/2) N/A
Hand 8  (1/485)  (2/8) N/A
Head 8  (5/485)  (2/8) N/A
Heart 8  (1/485)  (2/8) N/A
Hindbrain 8  (6/485)  (2/8) N/A
Hindlimb 8  (1/485)  (2/8) N/A
Liver 8  (1/485)  (2/8) N/A
Lung 8  (1/485)  (2/8) N/A
Mandibular process 8  (1/485)  (2/8) N/A
Maxillary process 8  (1/485)  (2/8) N/A
Midbrain 8  (1/485)  (2/8) N/A
Nose 2  (1/51)  (2/2) N/A
Oral cavity 8  (1/485)  (2/8) N/A
2  (7/25)  (2/2) N/A
Skeleton 2  (1/51)  (2/2) N/A
Skin 8  (1/485)  (2/8) N/A
Spinal cord 2  (1/50)  (2/2) N/A
Tail 8  (1/485)  (2/8) N/A
Tail somite 8  (1/485)  (2/8) N/A
Trachea 2  (1/50)  (2/2) N/A
Urinary system 2  (1/50)  (2/2) N/A

 Associated Images

X-ray: XRay Images Dorso Ventral
10 Images
X-ray: XRay Images Lateral Orientation
10 Images
Embryo LacZ: LacZ images wholemount
23 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Arih2tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Arih2tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Arih2tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Arih2tm2a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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