Genes Phenotypes

Gene: Arpc1b

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Name
actin related protein 2/3 complex, subunit 1B
MGI ID
MGI:1343142
Synonyms
L72 p41-ARC SOP2Hs
Viability
Homozygous - Viable
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (15) Measurements chart (386) All data table (1081)
Expression & images (0) Disease models (0) Histopathology (5) Order (1)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
decreased NK cell number Arpc1btm1a(EUCOMM)Wtsi HOM Early adult 2.45×10-06
fusion of vertebral arches Arpc1btm1a(EUCOMM)Wtsi HOM Early adult 3.87×10-05
increased eosinophil cell number Arpc1btm1a(EUCOMM)Wtsi HOM Early adult 2.05×10-05
increased effector memory CD4-positive, alpha-beta T cell number Arpc1btm1a(EUCOMM)Wtsi HOM Early adult 0.00
decreased body length Arpc1btm1a(EUCOMM)Wtsi HOM Early adult 3.27×10-06
increased red blood cell distribution width Arpc1btm1a(EUCOMM)Wtsi HOM Early adult 2.41×10-05
increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number Arpc1btm1a(EUCOMM)Wtsi HOM Early adult 0.00
decreased mean corpuscular hemoglobin Arpc1btm1a(EUCOMM)Wtsi HOM Early adult 8.32×10-05
increased plasma cell number Arpc1btm1a(EUCOMM)Wtsi HOM Early adult 0.00
increased effector memory T-helper cell number Arpc1btm1a(EUCOMM)Wtsi HOM Early adult 0.00
decreased mature B cell number Arpc1btm1a(EUCOMM)Wtsi HOM Early adult 0.00
decreased CD8-positive, alpha-beta T cell number Arpc1btm1a(EUCOMM)Wtsi HOM Early adult 2.05×10-05
vertebral fusion Arpc1btm1a(EUCOMM)Wtsi HOM Early adult 1.11×10-05
increased memory-marker CD4-negative NK T cell number Arpc1btm1a(EUCOMM)Wtsi HOM Early adult 0.00
decreased circulating insulin level Arpc1btm1a(EUCOMM)Wtsi HOM Early adult 1.34×10-05

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Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

DSS Histology
8 Images
Spleen Immunophenotyping: Images associated with FACS analysis
46 Images
Mesenteric Lymph Node Immunophenotyping: Images associated with FACS analysis
24 Images
X-ray: XRay Images Skull Lateral Orientation
17 Images
X-ray: XRay Images Whole Body Lateral Orientation
34 Images
Eye Morphology: Images Ophthalmoscopy
1 Images
Eye Morphology: Images Slit Lamp
1 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
16 Images
X-ray: XRay Images Forepaw
16 Images
X-ray: XRay Images Whole Body Dorso Ventral
49 Images
Legacy Phenotype Associated Images
Arpc1btm1a(EUCOMM)Wtsi
HOM, Male, WTSI
Arpc1btm1a(EUCOMM)Wtsi
HOM, Male, WTSI
Arpc1btm1a(EUCOMM)Wtsi
HOM, Male, WTSI
Arpc1btm1a(EUCOMM)Wtsi
HOM, Male, WTSI
Arpc1btm1a(EUCOMM)Wtsi
HOM, Male, WTSI

View all 69 images

Arpc1btm1a(EUCOMM)Wtsi
foot, abnormal autopod morphology, WT, Male, WTSI
Arpc1btm1a(EUCOMM)Wtsi
eye, abnormal eye morphology, eye opacity, corneal opacity, HOM, Female, WTSI
Arpc1btm1a(EUCOMM)Wtsi
head, HOM, Female, WTSI
Arpc1btm1a(EUCOMM)Wtsi
abnormal eye morphology, eye opacity, corneal opacity, HOM, Male, WTSI
Arpc1btm1a(EUCOMM)Wtsi
corneal opacity, HOM, Female, WTSI
Arpc1btm1a(EUCOMM)Wtsi
persistence of hyaloid vascular system, HOM, Male, WTSI
Arpc1btm1a(EUCOMM)Wtsi
back skin, HOM, Female, WTSI

 Disease Models

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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Kidney - process of degenerative change Arpc1btm1a(EUCOMM)Wtsi HOM Early adult
Pancreas - MPATH diagnostic term vasculitis Arpc1btm1a(EUCOMM)Wtsi HOM Early adult
Pancreas - inflammation Arpc1btm1a(EUCOMM)Wtsi HOM Early adult
Kidney - MPATH diagnostic term glomerulonephritis Arpc1btm1a(EUCOMM)Wtsi HOM Early adult
Testes - atrophy Arpc1btm1a(EUCOMM)Wtsi HOM Early adult

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Arpc1btm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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