Genes Phenotypes

Gene: Spop

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Name
speckle-type POZ protein
MGI ID
MGI:1343085
Synonyms
TEF2 Pcif1
Viability
Homozygous - Lethal
View
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (6) Measurements chart (141) All data table (308)
Expression & images (29) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
small thymus Spoptm1b(KOMP)Wtsi HET postnatal 0.00
decreased respiratory quotient Spoptm1b(KOMP)Wtsi HET postnatal 1.27×10-06
preweaning lethality, complete penetrance Spoptm1b(KOMP)Wtsi HOM n/a 0.00
increased circulating potassium level Spoptm1b(KOMP)Wtsi HET postnatal 6.71×10-05
abnormal embryo size Spoptm1b(KOMP)Wtsi HET embryonic day 15.5 0.00
small adrenal glands Spoptm1b(KOMP)Wtsi HET postnatal 0.00

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Viewing: all phenotypes
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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/51) N/A
Brain 8  (6/485)  (2/9) N/A
Central nervous system ganglion 2  (1/51)  (2/2) N/A
Ear 8  (1/485)  (2/9) N/A
Embryo 8  (1/485)  (2/9) N/A
Eye 8  (1/485)  (2/9) N/A
Foot 8  (1/485) N/A
Forebrain 8  (1/485)  (2/9) N/A
Forelimb 8  (1/485)  (2/9) N/A
Gut 2  (1/50)  (2/2) N/A
Hand 8  (1/485) N/A
Head 8  (5/485) N/A
Heart 8  (1/485)  (2/9) N/A
Hindbrain 8  (6/485)  (2/9) N/A
Hindlimb 8  (1/485)  (2/9) N/A
Liver 8  (1/485) N/A
Lung 8  (1/485)  (2/9) N/A
Mandibular process 8  (1/485)  (2/9) N/A
Maxillary process 8  (1/485) N/A
Midbrain 8  (1/485)  (2/9) N/A
Nose 2  (1/51) N/A
Oral cavity 8  (1/485)  (2/9) N/A
Skeleton 2  (1/51) N/A
Skin 8  (1/485) N/A
Spinal cord 2  (1/50)  (2/2) N/A
Tail 8  (1/485) N/A
Tail somite 8  (1/485)  (2/9) N/A
Trachea 2  (1/50)  (2/2) N/A
Urinary system 2  (1/50)  (2/2) N/A

 Associated Images

X-ray: XRay Images Dorso Ventral
16 Images
X-ray: XRay Images Lateral Orientation
32 Images
X-ray: XRay Images Hind Leg and Hip
16 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
16 Images
Gross Pathology and Tissue Collection
8 Images
Eye Morphology: Images Ophthalmoscopy
5 Images
Eye Morphology: Images Slit Lamp
2 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Spoptm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Spoptm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Spoptm1a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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