Gene: Spop

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Phenotype System Allele Zyg Sex Life Stage P Value
enlarged lymph nodes Spoptm1b(KOMP)Wtsi HET Early adult 0.00
preweaning lethality, complete penetrance Spoptm1b(KOMP)Wtsi HOM   Early adult 0.00
small adrenal glands Spoptm1b(KOMP)Wtsi HET Early adult 0.00
small thymus Spoptm1b(KOMP)Wtsi HET Early adult 0.00
decreased respiratory quotient Spoptm1b(KOMP)Wtsi HET Early adult 7.17×10-07
decreased food intake Spoptm1b(KOMP)Wtsi HET Early adult 2.95×10-05

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/63) N/A
Brain 8  (6/507)  (2/9) N/A
Central nervous system ganglion 2  (1/72)  (2/2) N/A
Ear 8  (1/507)  (2/9) N/A
Embryo 8  (1/508)  (2/9) N/A
Eye 8  (1/507)  (2/9) N/A
Footplate 8  (1/507) N/A
Forebrain 8  (1/507)  (2/9) N/A
Forelimb 8  (1/507)  (2/9) N/A
Gut 2  (1/58)  (2/2) N/A
Handplate 8  (1/507) N/A
Head 8  (5/507) N/A
Heart 8  (1/507)  (2/9) N/A
Hindbrain 8  (6/507)  (2/9) N/A
Hindlimb 8  (1/507)  (2/9) N/A
Liver 8  (1/502) N/A
Lung 8  (1/502)  (2/9) N/A
Mandibular process 8  (1/507)  (2/9) N/A
Maxillary process 8  (1/507) N/A
Midbrain 8  (1/507)  (2/9) N/A
Nose 2  (1/77) N/A
Oral cavity 8  (1/502)  (2/9) N/A
Skeleton 2  (1/77) N/A
Skin 8  (1/507) N/A
Spinal cord 2  (1/71)  (2/2) N/A
Tail 8  (1/507) N/A
Tail somite group 8  (1/507)  (2/9) N/A
Trachea 2  (1/58)  (2/2) N/A
Urinary system 2  (1/58)  (2/2) N/A

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
16 Images
Embryo LacZ: LacZ images wholemount
90 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
16 Images
X-ray: XRay Images Hind Leg and Hip
16 Images
Eye Morphology: Images Ophthalmoscopy
5 Images
X-ray: XRay Images Whole Body Lateral Orientation
16 Images
X-ray: XRay Images Skull Lateral Orientation
16 Images
Gross Pathology and Tissue Collection
8 Images
Eye Morphology: Images Slit Lamp
2 Images

 Disease Models

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 Histopathology

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Spoptm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Spoptm1a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Spoptm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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