Mthfd1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase
Physiological systems
20 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Mortality/aging Homeostasis/metabolism
18 No significant impact
4 Not tested
Data collections
Gene metrics:3Significant phenotypes
3Associated diseases
Expression examined in:51Adult tissues
62Embryo tissues
Human diseases caused by Mthfd1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
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