Gene: Kcnh3

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Name
potassium voltage-gated channel, subfamily H (eag-related), member 3
MGI ID
MGI:1341723
Synonyms
C030044P22Rik Melk2 ether a go-go like Elk2
View
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating HDL cholesterol level Kcnh3tm1.1(KOMP)Vlcg HOM postnatal 8.11×10-06
thrombocytopenia Kcnh3tm1.1(KOMP)Vlcg HOM postnatal 8.35×10-05
cardiovascular system phenotype Kcnh3tm1.1(KOMP)Vlcg HOM postnatal 2.04×10-05
decreased circulating HDL cholesterol level Kcnh3tm1.1(KOMP)Vlcg HOM postnatal 8.11×10-06
decreased heart rate variability Kcnh3tm1.1(KOMP)Vlcg HOM postnatal 3.78×10-05
decreased mean corpuscular volume Kcnh3tm1.1(KOMP)Vlcg HOM postnatal 9.15×10-05
increased hemoglobin content Kcnh3tm1.1(KOMP)Vlcg HOM postnatal 2.62×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (1/2) N/A
Aorta 2 No N/A
Bone 2 No N/A
Bone marrow 2 No N/A
Brain 2 No  (1/2) N/A
Brainstem 2 No  (1/2)  Section images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (1/2)  Section images
Cerebral cortex 2 No  (1/2)  Section images
Epididymis 2 No  (18/134) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (1/2)  Section images
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Main olfactory bulb 2 No  (1/2)  Section images
Mammary gland 2 No N/A
Midbrain 2 No  (1/2)  Section images
Olfactory lobe 2 No  (1/2)  Section images
Ovary 2 No  (1/584)  (1/2)  Section images
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Quadriceps 2 No N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (1/2)  Section images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No N/A
Submandibular gland 2 No  (2/132)  (1/2)  Section images
Testis 2 No  (2/584) N/A
Thalamus 2 No  (1/2)  Section images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
Vesicular gland 1 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485) N/A
Dorsal root ganglion 1  (1/47) N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485) N/A
Eye 2  (1/485) N/A
Foot 2  (1/485) N/A
Forebrain 2  (1/485) N/A
Forelimb 2  (1/485) N/A
Fronto-nasal process 1  (1/48) N/A
Hand 2  (1/485) N/A
Head 2  (5/485) N/A
Heart 2  (1/485) N/A
Hindbrain 2  (6/485) N/A
Hindlimb 2  (1/485) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485) N/A
Mandibular process 2  (1/485) N/A
Maxillary process 2  (1/485) N/A
Midbrain 2  (1/485) N/A
Nose 1  (1/51) N/A
Oral cavity 2  (1/485) N/A
Skin 2  (1/485) N/A
Spinal cord 1  (1/50) N/A
Tail 2  (1/485) N/A
Tail somite 2  (1/485) N/A

 Associated Images

X-ray: XRay Images Skull Dorso Ventral Orientation
33 Images
X-ray: XRay Images Lateral Orientation
33 Images
X-ray: XRay Images Forepaw
33 Images
X-ray: XRay Images Skull Lateral Orientation
33 Images
X-ray: XRay Images Dorso Ventral
33 Images
Electroretinography: Cone waveform (pdf format)
7 Images
Electroretinography: Rod waveform (pdf format)
7 Images
Original Image
Adult LacZ: LacZ Images Section
11 Images
Combined SHIRPA and Dysmorphology
7 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Kcnh3tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Kcnh3tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice
Kcnh3tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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