Atrn | attractin

GeneMGI:1341628Synonyms: Mgca

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Vision/eye Hematopoietic system Behavior/neurological Skeleton

17 No significant impact

3 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

increased mean corpuscular volume1 supporting datasetAtrntm1.1(KOMP)VlcghomozygoteEarly adult1.95x10-5 
decreased grip strength1 supporting datasetAtrntm1.1(KOMP)VlcghomozygoteEarly adult2.98x10-5 
increased mean corpuscular hemoglobin1 supporting datasetAtrntm1.1(KOMP)VlcghomozygoteEarly adult2.58x10-7 
increased bone mineral content1 supporting datasetAtrntm1.1(KOMP)VlcghomozygoteEarly adult4.86x10-5 
abnormal eye morphology1 supporting datasetAtrntm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

adrenal glandheterozygoteSection images
100% (2/2)0.7% (4/570)
aortaheterozygoten/a0% (0/2)0.19% (1/533)
bloodheterozygoten/a0% (0/2)0% (0/17)
bone marrowheterozygoten/a0% (0/2)0% (0/22)
brainheterozygoten/a100% (2/2)0.86% (5/579)
brainstemheterozygoten/an/a0.41% (2/490)
brown adipose tissueheterozygoten/a0% (0/2)0% (0/588)
cartilage tissueheterozygoten/an/a0.22% (1/454)
cecumheterozygoteSection images
100% (1/1)7.75% (22/284)
cerebellumheterozygoteSection images
100% (2/2)0.56% (3/532)
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Histopathology

IMPC related publications

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Atrntm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Atrntm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Atrntm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Atrntm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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