Gene: Tnks

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Name
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
MGI ID
MGI:1341087
Synonyms
4930554K12Rik D130072O21Rik mTNKS1 TANK1 tankyrase 1
Viability
N/A
Embryo viewer
N/A
Other links
Expression & images (0) Disease models (0) Order (2)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating bilirubin level Tnksem1(IMPC)Hmgu HOM Early adult 1.04×10-05
abnormal retina morphology Tnksem1(IMPC)Hmgu HOM Early adult 1.65×10-06
increased heart weight Tnksem1(IMPC)Hmgu HOM   Early adult 8.65×10-05
decreased circulating triglyceride level Tnksem1(IMPC)Hmgu HOM   Early adult 8.29×10-05
decreased circulating HDL cholesterol level Tnksem1(IMPC)Hmgu HOM Early adult 1.95×10-05
increased circulating alkaline phosphatase level Tnksem1(IMPC)Hmgu HOM Early adult 9.33×10-05
decreased total body fat amount Tnksem1(IMPC)Hmgu HOM Early adult 6.05×10-07
decreased total retina thickness Tnksem1(IMPC)Hmgu HOM   Early adult 8.76×10-06
increased fasting circulating glucose level Tnksem1(IMPC)Hmgu HOM Early adult 4.06×10-09
decreased circulating cholesterol level Tnksem1(IMPC)Hmgu HOM Early adult 2.20×10-05
increased lean body mass Tnksem1(IMPC)Hmgu HOM Early adult 1.62×10-06
decreased bone mineral density Tnksem1(IMPC)Hmgu HOM   Early adult 2.79×10-05
shortened PR interval Tnksem1(IMPC)Hmgu HOM Early adult 1.41×10-06
abnormal gait Tnksem1(IMPC)Hmgu HOM   Early adult 3.55×10-05
decreased circulating glucose level Tnksem1(IMPC)Hmgu HOM Early adult 2.12×10-06

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 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Tnksem1(IMPC)Hmgu Exon Deletion Mice
Tnkstm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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