Genes Phenotypes

Gene: Myh1

Name
myosin, heavy polypeptide 1, skeletal muscle, adult
MGI ID
MGI:1339711
Synonyms
myosin heavy chain 2X MYHC-IIX Myhs-f Myhs-f2 Myhsf2 A530084A17Rik MyHC-IId/x IId/x IId
Viability
Homozygous - Viable
Other links
MGI   Ensembl  
Significant phenotypes (22) All measurements (361) Expression & images (73) Disease models (0) Order (3)
View data by physiological system
Significant
Not Significant
Not tested
Body weight
Phenotype System Allele Zyg Sex Life Stage P Value
decreased body length Myh1tm1b(KOMP)Wtsi HOM postnatal 2.98×10-08
decreased leukocyte cell number Myh1tm1b(KOMP)Wtsi HOM postnatal 4.15×10-06
abnormal motor learning Myh1tm1b(KOMP)Wtsi HOM postnatal 2.90×10-05
increased or absent threshold for auditory brainstem response Myh1tm1b(KOMP)Wtsi HOM postnatal 3.90×10-05
abnormal behavioral response to light Myh1tm1b(KOMP)Wtsi HOM postnatal 3.02×10-12
decreased grip strength Myh1tm1b(KOMP)Wtsi HOM postnatal 1.20×10-20
decreased bone mineral density Myh1tm1b(KOMP)Wtsi HOM postnatal 0.00
decreased bone mineral content Myh1tm1b(KOMP)Wtsi HOM postnatal 0.00
absent startle reflex Myh1tm1b(KOMP)Wtsi HOM postnatal 5.74×10-14
decreased exploration in new environment Myh1tm1b(KOMP)Wtsi HOM postnatal 3.98×10-07
decreased prepulse inhibition Myh1tm1b(KOMP)Wtsi HOM postnatal 1.15×10-05
decreased lean body mass Myh1tm1b(KOMP)Wtsi HOM postnatal 0.00
decreased urine creatinine level Myh1tm1b(KOMP)Wtsi HOM postnatal 1.70×10-07
decreased startle reflex Myh1tm1b(KOMP)Wtsi HOM postnatal 1.66×10-22
abnormal bone structure Myh1tm1b(KOMP)Wtsi HOM postnatal 0.00
abnormal vocalization Myh1tm1b(KOMP)Wtsi HOM postnatal 1.42×10-08
increased hematocrit Myh1tm1b(KOMP)Wtsi HOM postnatal 1.11×10-05
abnormal sleep behavior Myh1tm1b(KOMP)Wtsi HOM postnatal 4.36×10-22
increased erythrocyte cell number Myh1tm1b(KOMP)Wtsi HOM postnatal 8.88×10-06
decreased total body fat amount Myh1tm1b(KOMP)Wtsi HOM postnatal 2.36×10-07
convulsive seizures Myh1tm1b(KOMP)Wtsi HOM postnatal 2.67×10-06
decreased anxiety-related response Myh1tm1b(KOMP)Wtsi HOM postnatal 2.26×10-10

Download data as:  TSV  XLS

Filtered by: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Epididymis 2 No  (18/134) N/A
Esophagus 2 No  (7/415)  (2/2) N/A
Eye 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No  (2/2) N/A
Skin 2 No N/A
Small intestine 2 No  (9/584)  (2/2) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No N/A
Submandibular gland 2 No  (2/132) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thalamus 2 No N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485) N/A
Dorsal root ganglion 2  (1/47) N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485) N/A
Eye 2  (1/485) N/A
Foot 2  (1/485) N/A
Forebrain 2  (1/485) N/A
Forelimb 2  (1/485) N/A
Fronto-nasal process 2  (1/48) N/A
Hand 2  (1/485) N/A
Head 2  (5/485) N/A
Heart 2  (1/485) N/A
Hindbrain 2  (6/485) N/A
Hindlimb 2  (1/485) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485) N/A
Mandibular process 2  (1/485) N/A
Maxillary process 2  (1/485) N/A
Midbrain 2  (1/485) N/A
Nose 2  (1/51) N/A
Oral cavity 2  (1/485) N/A
Skin 2  (1/485) N/A
Spinal cord 2  (1/50) N/A
Tail 2  (1/485) N/A
Tail somite 2  (1/485) N/A

 Associated Images

X-ray: XRay Images Skull Lateral Orientation
14 Images
Electroretinography 2: Rod and cone PDF
3 Images
X-ray: XRay Images Forepaw
14 Images
X-ray: XRay Images Lateral Orientation
14 Images
Sleep Wake: Wake state (bmp file)
10 Images
X-ray: XRay Images Dorso Ventral
14 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Myh1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Myh1tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Myh1tm2a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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