Gene: Myh1

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Name
myosin, heavy polypeptide 1, skeletal muscle, adult
MGI ID
MGI:1339711
Synonyms
MyHC-IId/x Myhs-f Myhs-f2 Myhsf2 A530084A17Rik IId/x IId myosin heavy chain 2X MYHC-IIX
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased thigmotaxis Myh1tm1b(KOMP)Wtsi HOM Early adult 2.49×10-08
decreased bone mineral density Myh1tm1b(KOMP)Wtsi HOM Early adult 0.00
abnormal auditory brainstem response Myh1tm1b(KOMP)Wtsi HOM   Early adult 2.00×10-08
abnormal bone structure Myh1tm1b(KOMP)Wtsi HOM Early adult 8.93×10-24
increased total body fat amount Myh1tm1b(KOMP)Wtsi HOM Early adult 1.62×10-17
decreased vertical activity Myh1tm1b(KOMP)Wtsi HOM Early adult 5.99×10-06
decreased body length Myh1tm1b(KOMP)Wtsi HOM Early adult 7.60×10-05
abnormal motor learning Myh1tm1b(KOMP)Wtsi HOM Early adult 1.89×10-05
decreased leukocyte cell number Myh1tm1b(KOMP)Wtsi HOM Early adult 6.23×10-05
decreased anxiety-related response Myh1tm1b(KOMP)Wtsi HOM   Early adult 1.09×10-09
decreased grip strength Myh1tm1b(KOMP)Wtsi HOM Early adult 0.00
abnormal sleep behavior Myh1tm1b(KOMP)Wtsi HOM Early adult 1.05×10-13
decreased prepulse inhibition Myh1tm1b(KOMP)Wtsi HOM   Early adult 1.97×10-05
decreased startle reflex Myh1tm1b(KOMP)Wtsi HOM Early adult 2.17×10-20
decreased urine creatinine level Myh1tm1b(KOMP)Wtsi HOM Early adult 1.65×10-14
decreased bone mineral content Myh1tm1b(KOMP)Wtsi HOM Early adult 5.20×10-23
decreased lean body mass Myh1tm1b(KOMP)Wtsi HOM Early adult 2.12×10-13
abnormal startle reflex Myh1tm1b(KOMP)Wtsi HOM Early adult 1.08×10-14
increased hematocrit Myh1tm1b(KOMP)Wtsi HOM   Early adult 2.13×10-05
abnormal motor coordination/balance Myh1tm1b(KOMP)Wtsi HOM   Early adult 4.86×10-05
decreased exploration in new environment Myh1tm1b(KOMP)Wtsi HOM Early adult 9.79×10-05
hypoactivity Myh1tm1b(KOMP)Wtsi HOM Early adult 1.14×10-08

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/590) N/A
Aorta 2 No  (1/590) N/A
Brain 2 No  (3/590) N/A
Brainstem 2 No  (2/590) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (3/590) N/A
Cerebral cortex 2 No  (2/590) N/A
Epididymis 2 No  (18/134) N/A
Esophagus 2 No  (7/415)  (2/2)  Section images
Eye 2 No N/A
Heart 2 No  (1/590) N/A
Hippocampus 2 No  (3/590) N/A
Hypothalamus 2 No  (2/590) N/A
Kidney 2 No  (20/590)  (2/2)  Section images
Large intestine 2 No  (10/590)  (2/2)  Section images
Liver 2 No N/A
Lower urinary tract 2 No  (1/590) N/A
Lung 2 No  (1/590) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No  (2/590) N/A
Ovary 2 No  (1/590)  (1/2)  Section images
Oviduct 2 No N/A
Pancreas 2 No  (5/590) N/A
Peripheral nervous system 2 No  (1/590) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/590) N/A
Prostate gland 2 No  (12/590) N/A
Skeletal muscle 2 No  (2/2)  Section images
Skin 2 No N/A
Small intestine 2 No  (9/590)  (2/2)  Section images
Spinal cord 2 No  (2/590) N/A
Spleen 2 No  (2/590) N/A
Stomach 2 No  (13/590) N/A
Striatum 2 No  (3/590) N/A
Submandibular gland 2 No  (2/132) N/A
Testis 2 No  (5/590)  (1/2)  Section images
Thalamus 2 No N/A
Thymus 2 No N/A
Thyroid gland 2 No  (16/590)  Section images
Trachea 2 No  (2/590) N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/506) N/A
Dorsal root ganglion 2  (1/61) N/A
Ear 2  (1/506) N/A
Embryo 2  (1/507) N/A
Eye 2  (1/506) N/A
Foot 2  (1/506) N/A
Forebrain 2  (1/506) N/A
Forelimb 2  (1/506) N/A
Fronto-nasal process 2  (1/62) N/A
Hand 2  (1/506) N/A
Head 2  (5/506) N/A
Heart 2  (1/506) N/A
Hindbrain 2  (6/506) N/A
Hindlimb 2  (1/506) N/A
Liver 2  (1/504) N/A
Lung 2  (1/504) N/A
Mandibular process 2  (1/506) N/A
Maxillary process 2  (1/506) N/A
Midbrain 2  (1/506) N/A
Nose 2  (1/76) N/A
Oral cavity 2  (1/504) N/A
Skin 2  (1/506) N/A
Spinal cord 2  (1/73) N/A
Tail 2  (1/506) N/A
Tail somite 2  (1/506) N/A

 Associated Images

Sleep Wake: Wake state (bmp file)
10 Images
X-ray: XRay Images Forepaw
15 Images
X-ray: XRay Images Whole Body Lateral Orientation
15 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
15 Images
X-ray: XRay Images Whole Body Dorso Ventral
15 Images
Original Image
Adult LacZ: LacZ Images Section
8 Images
X-ray: XRay Images Skull Lateral Orientation
15 Images
Eye Morphology: Images Ophthalmoscopy
2 Images
Eye Morphology: Images Slit Lamp
1 Images
Electroretinography 2: Rod and cone PDF
3 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Myh1tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Myh1tm2a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Myh1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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