Gene: Myh1

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Name
myosin, heavy polypeptide 1, skeletal muscle, adult
MGI ID
MGI:1339711
Synonyms
MyHC-IId/x Myhs-f Myhs-f2 Myhsf2 A530084A17Rik MYHC-IIX myosin heavy chain 2X IId IId/x
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal startle reflex Myh1tm1b(KOMP)Wtsi HOM Early adult 1.10×10-14
increased erythrocyte cell number Myh1tm1b(KOMP)Wtsi HOM Early adult 9.60×10-05
abnormal bone structure Myh1tm1b(KOMP)Wtsi HOM Early adult 9.28×10-19
decreased exploration in new environment Myh1tm1b(KOMP)Wtsi HOM Early adult 9.67×10-05
decreased thigmotaxis Myh1tm1b(KOMP)Wtsi HOM Early adult 4.08×10-09
decreased startle reflex Myh1tm1b(KOMP)Wtsi HOM Early adult 8.53×10-14
decreased anxiety-related response Myh1tm1b(KOMP)Wtsi HOM   Early adult 1.45×10-09
decreased leukocyte cell number Myh1tm1b(KOMP)Wtsi HOM Early adult 1.58×10-08
abnormal motor learning Myh1tm1b(KOMP)Wtsi HOM   Early adult 1.97×10-05
decreased grip strength Myh1tm1b(KOMP)Wtsi HOM Early adult 0.00
increased hemoglobin content Myh1tm1b(KOMP)Wtsi HOM Early adult 1.36×10-05
decreased bone mineral density Myh1tm1b(KOMP)Wtsi HOM Early adult 2.42×10-33
decreased body length Myh1tm1b(KOMP)Wtsi HOM Early adult 1.31×10-06
decreased vertical activity Myh1tm1b(KOMP)Wtsi HOM Early adult 3.65×10-05
abnormal auditory brainstem response Myh1tm1b(KOMP)Wtsi HOM   Early adult 2.78×10-08
abnormal sleep behavior Myh1tm1b(KOMP)Wtsi HOM Early adult 1.03×10-13
decreased prepulse inhibition Myh1tm1b(KOMP)Wtsi HOM   Early adult 1.07×10-05
decreased urine creatinine level Myh1tm1b(KOMP)Wtsi HOM Early adult 1.65×10-14
decreased lean body mass Myh1tm1b(KOMP)Wtsi HOM Early adult 1.09×10-10
abnormal motor coordination/balance Myh1tm1b(KOMP)Wtsi HOM   Early adult 4.78×10-05
hypoactivity Myh1tm1b(KOMP)Wtsi HOM Early adult 1.87×10-08
increased total body fat amount Myh1tm1b(KOMP)Wtsi HOM Early adult 5.23×10-09
decreased bone mineral content Myh1tm1b(KOMP)Wtsi HOM Early adult 3.37×10-17
increased hematocrit Myh1tm1b(KOMP)Wtsi HOM   Early adult 3.38×10-06

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
2 No  (4/583) N/A
2 No  (1/583) N/A
2 No  (4/583) N/A
2 No  (2/583) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (3/583) N/A
2 No  (2/583) N/A
2 No  (18/132) N/A
2 No  (7/407)  (2/2)  Section images
2 No N/A
2 No  (2/583) N/A
2 No  (3/583) N/A
2 No  (2/583) N/A
2 No  (21/583)  (2/2)  Section images
2 No  (10/583)  (2/2)  Section images
2 No N/A
2 No  (1/583) N/A
2 No  (2/583) N/A
2 No  (1/583) N/A
2 No N/A
2 No N/A
2 No  (2/583) N/A
2 No  (1/583)  (1/2)  Section images
2 No N/A
2 No  (5/583) N/A
2 No  (2/583) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (12/583) N/A
2 No  (2/2)  Section images
2 No  (1/583) N/A
2 No  (9/583)  (2/2)  Section images
2 No  (3/583) N/A
2 No  (3/583) N/A
2 No  (13/583) N/A
2 No  (3/583) N/A
2 No  (2/130) N/A
2 No  (6/583)  (1/2)  Section images
2 No N/A
2 No  (1/583) N/A
2 No  (17/583)  Section images
2 No  (3/583) N/A
2 No N/A
2 No N/A
2 No N/A
2 No N/A
2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (6/505) N/A
2  (1/60) N/A
2  (1/505) N/A
2  (1/506) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/61) N/A
2  (1/505) N/A
2  (5/505) N/A
2  (1/505) N/A
2  (6/505) N/A
2  (1/505) N/A
2  (1/503) N/A
2  (1/503) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/75) N/A
2  (1/503) N/A
2  (1/505) N/A
2  (1/72) N/A
2  (1/505) N/A
2  (1/505) N/A

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
15 Images
X-ray: XRay Images Whole Body Lateral Orientation
15 Images
X-ray: XRay Images Skull Lateral Orientation
15 Images
X-ray: XRay Images Forepaw
15 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
15 Images
Sleep Wake: Wake state (bmp file)
10 Images
Eye Morphology: Images Ophthalmoscopy
2 Images
Adult LacZ: LacZ Images Section
8 Images
Electroretinography 2: Rod and cone PDF
3 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
5 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Myh1tm2a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Myh1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Myh1tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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