Gene: Acvr1b

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Name
activin A receptor, type 1B
MGI ID
MGI:1338944
Synonyms
ActR-IB Acvrlk4 SKR2 ActRIB Alk4
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Acvr1btm1.1(KOMP)Vlcg HOM   Early adult 0.00
small adrenal glands Acvr1btm1.1(KOMP)Vlcg HET Early adult 0.00
increased prepulse inhibition Acvr1btm1.1(KOMP)Vlcg HET   Early adult 3.21×10-07
enlarged lymph nodes Acvr1btm1.1(KOMP)Vlcg HET Early adult 0.00
small testis Acvr1btm1.1(KOMP)Vlcg HET Early adult 0.00
abnormal uterus morphology Acvr1btm1.1(KOMP)Vlcg HET Early adult 0.00
embryonic lethality prior to tooth bud stage Acvr1btm1.1(KOMP)Vlcg HOM   E12.5 0.00
abnormal coat/ hair morphology Acvr1btm1.1(KOMP)Vlcg HET Early adult 3.84×10-05

Download data as:  TSV  XLS

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
2 No  (4/583) N/A
2 No  (1/583) N/A
2 No  (4/583) N/A
2 No  (2/583) N/A
2 No  (1/583) N/A
2 No  (3/583) N/A
2 No  (2/583) N/A
2 No  (7/407) N/A
2 No N/A
2 No  (2/583) N/A
2 No  (3/583) N/A
2 No  (2/583) N/A
2 No  (21/583)  (1/2) N/A
2 No  (10/583)  (1/2) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (2/583) N/A
2 No  (1/583) N/A
2 No N/A
2 No  (2/583) N/A
2 No  (1/583) N/A
2 No N/A
2 No  (5/583) N/A
2 No  (2/583) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (12/583)  (1/2) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (9/583) N/A
2 No  (3/583) N/A
2 No  (3/583) N/A
2 No  (13/583) N/A
2 No  (3/583) N/A
2 No  (6/583) N/A
2 No  (1/583) N/A
2 No  (17/583)  (2/2)  Section images
2 No  (3/583)  (1/2)  Section images
2 No N/A
2 No N/A
2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
16 Images
X-ray: XRay Images Whole Body Lateral Orientation
32 Images
Eye Morphology: Images Ophthalmoscopy
4 Images
X-ray: XRay Images Hind Leg and Hip
16 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
16 Images
Gross Pathology and Tissue Collection
10 Images
Adult LacZ: LacZ Images Section
4 Images
Eye Morphology: Images Slit Lamp
5 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Acvr1btm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Acvr1btm1(NCOM)Mfgc Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Acvr1btm442836(L1L2_Bact_P) Targeting vectors
Acvr1btm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells

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