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Genes Phenotypes Help, News, Blog

Gene: Cacna2d3

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Name
calcium channel, voltage-dependent, alpha2/delta subunit 3
MGI ID
MGI:1338890
Synonyms
alpha 2 delta-3 alpha2delta3
Viability
Data available
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (2) Measurements chart (243) All data table (919)
Expression & images (73) Disease models (0) Histopathology (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating sodium level Cacna2d3tm1b(KOMP)Wtsi HET Early adult 4.68×10-07
decreased circulating glucose level Cacna2d3tm1b(KOMP)Wtsi HET Early adult 2.19×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583) N/A
Aorta 2 No  (1/583)  (2/2)  Section images
Brain 2 No  (4/583)  (1/2)  Section images
Brainstem 2 No  (2/583)  (2/2)  Section images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/583) N/A
Cerebellum 2 No  (3/583) N/A
Cerebral cortex 2 No  (2/583) N/A
Epididymis 2 No  (18/132)  (1/2)  Section images
Esophagus 2 No  (7/407) N/A
Eye 2 No N/A
Heart 2 No  (2/583) N/A
Hippocampus 2 No  (3/583) N/A
Hypothalamus 2 No  (2/583) N/A
Kidney 2 No  (21/583)  (2/2)  Section images
Large intestine 2 No  (10/583)  (2/2)  Section images
Liver 2 No N/A
Lower urinary tract 2 No  (1/583) N/A
Lung 2 No  (2/583) N/A
Lymph node 2 No  (1/583) N/A
Mammary gland 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No  (2/583) N/A
Ovary 2 No  (1/583)  (1/2)  Section images
Oviduct 2 No  (1/2)  Section images
Pancreas 2 No  (5/583) N/A
Peripheral nervous system 2 No  (2/583) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/583) N/A
Prostate gland 2 No  (12/583) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (1/583) N/A
Small intestine 2 No  (9/583)  (2/2)  Section images
Spinal cord 2 No  (3/583) N/A
Spleen 2 No  (3/583)  (1/2)  Section images
Stomach 2 No  (13/583)  (2/2)  Section images
Striatum 2 No  (3/583) N/A
Submandibular gland 2 No  (2/130)  (1/2)  Section images
Testis 2 No  (6/583)  (1/2)  Section images
Thalamus 2 No N/A
Thymus 2 No  (1/583) N/A
Thyroid gland 2 No  (17/583) N/A
Trachea 2 No  (3/583) N/A
Urinary bladder 2 No  (2/2)  Section images
Uterus 2 No  (1/2)  Section images
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
cardiovascular system (1)
Aorta expression
MA:0000062
digestive system (4)
Large Intestine expression
MA:0000333
exocrine system (1)
Submandibular Gland expression
MA:0001589
immune system (1)
Spleen expression
MA:0000141
nervous system (2)
Brain expression
MA:0000168
postnatal mouse (15)
Aorta expression
MA:0000062
reproductive system (5)
Epididymis expression
MA:0000397
respiratory system (1)
Submandibular Gland expression
MA:0001589
trunk (12)
Aorta expression
MA:0000062
urinary system (2)
Kidney expression
MA:0000368
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (6/505) N/A
2  (1/60) N/A
2  (1/505) N/A
2  (1/506)  (2/3)  Wholemount images
2  (1/505) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/61) N/A
2  (1/505) N/A
2  (5/505) N/A
2  (1/505)  (1/3) N/A
2  (6/505) N/A
2  (1/505) N/A
2  (1/503) N/A
2  (1/503) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/75) N/A
2  (1/503) N/A
2  (1/505) N/A
2  (1/72) N/A
2  (1/505) N/A
2  (1/505) N/A
embryo or Unassigned (12)
Embryo expression

 Associated Images

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X-ray: XRay Images Skull Lateral Orientation
19 Images
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X-ray: XRay Images Whole Body Lateral Orientation
19 Images
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X-ray: XRay Images Skull Dorso Ventral Orientation
19 Images
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X-ray: XRay Images Forepaw
19 Images
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Original Image
Adult LacZ: LacZ Images Section
15 Images
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X-ray: XRay Images Whole Body Dorso Ventral
19 Images
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Embryo LacZ: LacZ images wholemount
12 Images
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Eye Morphology: Images Ophthalmoscopy
1 Images
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Sleep Wake: Wake state (bmp file)
3 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
1 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Histopathology

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Cacna2d3tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Cacna2d3tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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