Gfpt2 | glutamine fructose-6-phosphate transaminase 2

GeneMGI:1338883Synonyms: GFAT2

Physiological systems

19 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological Skeleton Craniofacial Cardiovascular system

11 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased red blood cell distribution width1 supporting datasetGfpt2tm1b(EUCOMM)WtsihomozygoteEarly adult8.23x10-8 
increased fasting circulating glucose level1 supporting datasetGfpt2tm1b(EUCOMM)WtsihomozygoteEarly adult4.45x10-9 
abnormal tooth morphology1 supporting datasetGfpt2tm1b(EUCOMM)WtsihomozygoteEarly adult3.88x10-9 
abnormal vocalization1 supporting datasetGfpt2tm1b(EUCOMM)WtsihomozygoteEarly adult4.28x10-5 
abnormal lens morphology2 supporting datasetsGfpt2tm1b(EUCOMM)WtsihomozygoteEarly adult6.05x10-7 
abnormal retina vasculature morphology1 supporting datasetGfpt2tm1b(EUCOMM)WtsihomozygoteEarly adult5.41x10-7 
decreased circulating serum albumin level1 supporting datasetGfpt2tm1b(EUCOMM)WtsihomozygoteEarly adult4.28x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Gfpt2tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Gfpt2tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Gfpt2tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Gfpt2tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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