P2rx4 | purinergic receptor P2X, ligand-gated ion channel 4
Physiological systems
20 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Hematopoietic system Skeleton
18 No significant impact
4 Not tested
Data collections
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
0Embryo tissues
| abnormal clavicle morphology | 1 supporting dataset | P2rx4tm1b(EUCOMM)Wtsi | homozygote | Early adult | 1.07x10-5 | ||
| decreased mean corpuscular volume | 1 supporting dataset | P2rx4tm1b(EUCOMM)Wtsi | homozygote | Early adult | 2.05x10-5 |
| | | | | | | | | | |
| adrenal gland | heterozygote | n/a | 100% (2/2) | 0.7% (4/570) |
| aorta | heterozygote | n/a | 100% (2/2) | 0.19% (1/533) |
| bone | heterozygote | n/a | 100% (2/2) | 0% (0/394) |
| brain | heterozygote | n/a | 100% (2/2) | 0.86% (5/579) |
| brainstem | heterozygote | n/a | 100% (2/2) | 0.41% (2/490) |
| brown adipose tissue | heterozygote | n/a | 0% (0/2) | 0% (0/588) |
| cartilage tissue | heterozygote | n/a | 100% (2/2) | 0.22% (1/454) |
| cerebellum | heterozygote | n/a | 100% (2/2) | 0.56% (3/532) |
| cerebral cortex | heterozygote | n/a | 100% (2/2) | 0.41% (2/491) |
| esophagus | heterozygote | n/a | 100% (2/2) | 1.67% (7/419) |
External links
No external links available for P2rx4.
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| P2rx4tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| P2rx4tm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| P2rx4tm1c(EUCOMM)Wtsi | Wild type floxed exon (post-Flp) | | mouse |
| P2rx4tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | mouse |
| P2rx4tm40299(L1L2_gt2) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |