Gene: P2rx4

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Name
purinergic receptor P2X, ligand-gated ion channel 4
MGI ID
MGI:1338859
Synonyms
P2X4 D5Ertd444e
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased total body fat amount P2rx4tm1b(EUCOMM)Wtsi HOM Early adult 3.04×10-06
decreased bone mineral content P2rx4tm1b(EUCOMM)Wtsi HOM Early adult 7.17×10-05
abnormal clavicle morphology P2rx4tm1b(EUCOMM)Wtsi HOM Early adult 1.19×10-05
abnormal bone mineralization P2rx4tm1b(EUCOMM)Wtsi HOM Early adult 9.67×10-05
decreased heart weight P2rx4tm1b(EUCOMM)Wtsi HOM Early adult 2.56×10-06

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/589)  (2/2)  Wholemount images
Aorta 2 No  (1/589)  (2/2)  Wholemount images
Bone 2 No  (2/2)  Wholemount images
Brain 2 No  (3/589)  (2/2) N/A
Brainstem 2 No  (2/589)  (2/2) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2)  Wholemount images
Cerebellum 2 No  (3/589)  (2/2) N/A
Cerebral cortex 2 No  (2/589)  (2/2) N/A
Esophagus 2 No  (7/415)  (2/2)  Wholemount images
Eye 2 No N/A
Gall bladder 2 No  (2/2)  Wholemount images
Heart 2 No  (1/589)  (2/2)  Wholemount images
Hippocampus 2 No  (3/589)  (2/2) N/A
Hypothalamus 2 No  (2/589)  (2/2) N/A
Kidney 2 No  (20/589)  (2/2)  Wholemount images
Large intestine 2 No  (10/589)  (2/2)  Wholemount images
Liver 2 No N/A
Lower urinary tract 2 No  (1/589)  (2/2) N/A
Lung 2 No  (1/589)  (2/2)  Wholemount images
Lymph node 2 No  (2/2)  Wholemount images
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/589)  (2/2) N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/589)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/589)  (2/2)  Wholemount images
Parathyroid gland 2 No  (2/2)  Wholemount images
Peripheral nervous system 2 No  (1/589)  (2/2)  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/589)  (2/2)  Wholemount images
Prostate gland 2 No  (12/589)  (1/2) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Wholemount images
Small intestine 2 No  (9/589)  (2/2)  Wholemount images
Spinal cord 2 No  (2/589)  (2/2)  Wholemount images
Spleen 2 No  (2/589) N/A
Stomach 2 No  (13/589)  (2/2)  Wholemount images
Striatum 2 No  (3/589)  (2/2) N/A
Testis 2 No  (5/589)  (1/2) N/A
Thymus 2 No  (2/2)  Wholemount images
Thyroid gland 2 No  (16/589)  (2/2)  Wholemount images
Trachea 2 No  (2/589)  (2/2)  Wholemount images
Uterus 2 No  (1/2) N/A
Vascular system 2 No  (2/2)  Wholemount images
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

Echo: M-Mode Images
32 Images
Adult LacZ: LacZ Images Wholemount
25 Images
X-ray: XRay Images Whole Body Lateral Orientation
14 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
13 Images
X-ray: XRay Images Whole Body Dorso Ventral
13 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
P2rx4tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
P2rx4tm1c(EUCOMM)Wtsi Wild type floxed exon (post-Flp) Mice
P2rx4tm40299(L1L2_gt2) Targeting vectors
P2rx4tm1e(EUCOMM)Wtsi Targeted, non-conditional allele Mice
P2rx4tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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