Mthfd2 | methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase
Physiological systems
21 / 24 physiological systems tested
10 Significantly impacted by the knock-out
Vision/eye Liver/biliary system Mortality/aging Integument Homeostasis/metabolism Skeleton Embryo Craniofacial Cardiovascular system Growth/size/body region
11 No significant impact
3 Not tested
Data collections
Gene metrics:21Significant phenotypes
0Associated diseases
Expression examined in:50Adult tissues
62Embryo tissues
Human diseases caused by Mthfd2 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
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