Bmp10 | bone morphogenetic protein 10

GeneMGI:1338820Synonyms: b2b2711Clo

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological Mortality/aging

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, complete penetrance	1 supporting dataset	Bmp10^{tm3b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
decreased exploration in new environment	1 supporting dataset	Bmp10^{tm3b(EUCOMM)Hmgu}	heterozygote	Early adult	2.69x10^-7
improved glucose tolerance	2 supporting datasets	Bmp10^{tm3b(EUCOMM)Hmgu}	heterozygote	Early adult	5.61x10^-8
decreased circulating creatinine level	1 supporting dataset	Bmp10^{tm3b(EUCOMM)Hmgu}	heterozygote	Early adult	2.55x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Bmp10.

Associated images

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Histopathology

There is no histopathology data found for Bmp10.

IMPC related publications

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External links

No external links available for Bmp10.

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*Bmp10^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Bmp10^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Bmp10^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Bmp10^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Bmp10^{tm3a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Bmp10^{tm3b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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