Gene: Aire

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Name
autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)
MGI ID
MGI:1338803
Synonyms
N/A
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal cholesterol homeostasis Airetm1.1(NCOM)Mfgc HET Early adult 7.01×10-13
decreased prepulse inhibition Airetm1.1(NCOM)Mfgc HOM Early adult 3.05×10-05
abnormal eye morphology Airetm1.1(NCOM)Mfgc HOM Early adult 0.00
increased monocyte cell number Airetm1.1(NCOM)Mfgc HOM Early adult 1.38×10-05

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Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

Eye Morphology: Images Ophthalmoscopy
13 Images
X-ray: XRay Images Skull Lateral Orientation
17 Images
X-ray: XRay Images Whole Body Lateral Orientation
17 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
17 Images
Immunophenotyping: Panel A FCS file(s)
8 Images
X-ray: XRay Images Whole Body Dorso Ventral
17 Images
Gross Pathology and Tissue Collection
16 Images
Histopathology
13 Images
Immunophenotyping: Panel B FCS file(s)
8 Images
Eye Morphology: Images Slit Lamp
1 Images

 Disease Models

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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Salivary gland - inflammation Airetm1.1(NCOM)Mfgc HOM Early adult

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MGI Allele Allele Type Produced
Airetm1.1(NCOM)Mfgc Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Airetm1(NCOM)Mfgc Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Airetm2a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells