Gene: Aire

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Name
autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)
MGI ID
MGI:1338803
Synonyms
N/A
View
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal eye morphology Airetm1.1(NCOM)Mfgc HOM postnatal 0.00
embryonic lethality prior to tooth bud stage Airetm1.1(NCOM)Mfgc HOM embryonic day 12.5 0.00
embryonic lethality prior to organogenesis Airetm1.1(NCOM)Mfgc HOM embryonic day 9.5 0.00

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/51) N/A
Brain 3  (6/485) N/A
Central nervous system ganglion 2  (1/51) N/A
Ear 3  (1/485) N/A
Embryo 3  (1/485) N/A
Eye 3  (1/485) N/A
Foot 3  (1/485) N/A
Forebrain 3  (1/485) N/A
Forelimb 3  (1/485) N/A
Gut 2  (1/50) N/A
Hand 3  (1/485) N/A
Head 3  (5/485) N/A
Heart 3  (1/485) N/A
Hindbrain 3  (6/485) N/A
Hindlimb 3  (1/485) N/A
Liver 3  (1/485) N/A
Lung 3  (1/485) N/A
Mandibular process 3  (1/485) N/A
Maxillary process 3  (1/485) N/A
Midbrain 3  (1/485) N/A
Nose 2  (1/51) N/A
Oral cavity 3  (1/485) N/A
2  (7/25) N/A
Skeleton 2  (1/51) N/A
Skin 3  (1/485) N/A
Spinal cord 2  (1/50) N/A
Tail 3  (1/485) N/A
Tail somite 3  (1/485) N/A
Trachea 2  (1/50) N/A
Urinary system 2  (1/50) N/A

 Associated Images

X-ray: XRay Images Skull Dorso Ventral Orientation
17 Images
X-ray: XRay Images Skull Lateral Orientation
17 Images
X-ray: XRay Images Dorso Ventral
17 Images
X-ray: XRay Images Lateral Orientation
17 Images
Eye Morphology: Images Ophthalmoscopy
13 Images
Gross Pathology and Tissue Collection
16 Images
Histopathology
13 Images
Eye Morphology: Images Slit Lamp
1 Images
Embryo LacZ: LacZ images wholemount
4 Images

 Disease Models

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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Salivary gland - inflammation Airetm1.1(NCOM)Mfgc HOM postnatal

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Airetm1(NCOM)Mfgc Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Airetm1.1(NCOM)Mfgc Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Airetm2a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells