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Gene: Hivep2 MGI:1338076

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Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
human immunodeficiency virus type I enhancer binding protein 2
Synonyms:
Shn-2,  MIBP1,  Gm20114,  Schnurri-2

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IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Hivep2 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

The table below shows human diseases associated to Hivep2 by orthology or direct annotation.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Intellectual Developmental Disorder, Autosomal Dominant 43
Aggressive behavior, Failure to thrive, Hyperactivity, Impulsivity OMIM:616977

The table below shows human diseases predicted to be associated to Hivep2 by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Okt4 Epitope Deficiency
Abnormal T cell morphology OMIM:613949
Immunodeficiency 15A
Decreased proportion of CD8-positive T cells, Decreased proportion of memory B cells, Decreased p... OMIM:618204
Severe Combined Immunodeficiency Due To Foxn1 Deficiency
T lymphocytopenia ORPHA:169095
Combined Immunodeficiency, X-Linked
Abnormal T cell count, Decreased proportion of CD8-positive T cells, Decreased proportion of CD4-... OMIM:312863
Wiskott-Aldrich Syndrome 2
Decreased proportion of CD8-positive T cells, Thrombocytopenia OMIM:614493
Immunodeficiency 116
Absence of CD8-positive T cells OMIM:608957
Immunodeficiency, partial combined, with absence of hla determinantsand beta-2-microglobulin from lymphocytes
T lymphocytopenia OMIM:242870
Combined Cellular And Humoral Immune Defects With Granulomas
T lymphocytopenia, B lymphocytopenia OMIM:233650
Splenomegaly Syndrome With Splenic Germinal Center Hypoplasia And Reduced Circulating T Helper Cells
Decreased helper T cell proportion, Pancytopenia, Splenomegaly, Hypersplenism OMIM:183350
22q11 deletion syndrome (Velocardiofacial / DiGeorge syndrome)
T lymphocytopenia DECIPHER:16
T-Cell Immunodeficiency, Congenital Alopecia, And Nail Dystrophy
T lymphocytopenia, Decreased helper T cell proportion OMIM:601705
T-Cell Lymphopenia, Infantile, With Or Without Nail Dystrophy, Autosomal Dominant
Abnormally low T cell receptor excision circle level, T lymphocytopenia OMIM:618806
Immunodeficiency 48
Impaired lymphocyte transformation with phytohemagglutinin, Abnormal B cell count, Splenomegaly, ... OMIM:269840
Immunodeficiency 19
Abnormal B cell morphology, T lymphocytopenia, Abnormal natural killer cell morphology OMIM:615617
Reticular Dysgenesis
Lymphopenia, Leukopenia, Congenital agranulocytosis, Hypoplasia of the thymus OMIM:267500
Immunodeficiency, Ovarian Dysgenesis, And Pulmonary Fibrosis
Decreased proportion of CD8-positive T cells, Decreased proportion of CD4-positive helper T cells OMIM:611926
Intellectual Disability-Expressive Aphasia-Facial Dysmorphism Syndrome
EEG abnormality, Hyperactivity, Abnormal social behavior ORPHA:436151
Immunodeficiency 76
Lymphopenia, Splenomegaly, Lymphadenopathy, B lymphocytopenia, T lymphocytopenia OMIM:619164
Immunodeficiency 52
Increased proportion of gamma-delta T cells, Lymphopenia, Abnormal B cell count, Decreased propor... OMIM:617514
T-B+ Severe Combined Immunodeficiency Due To Il-7Ralpha Deficiency
Decreased proportion of CD8-positive T cells, Lymphopenia, Hepatosplenomegaly, Decreased proporti... ORPHA:169154
Immunodeficiency 105
Reduced natural killer cell count, Absence of lymph node germinal center, Lymphopenia, Pancytopen... OMIM:619924
Lung Disease, Immunodeficiency, And Chromosome Breakage Syndrome
Decreased proportion of CD8-positive T cells, Hypoplasia of the thymus, Decreased proportion of C... OMIM:617241
Immunodeficiency 97 With Autoinflammation
Decreased proportion of CD4+CD25+ regulatory T cells, Reduced natural killer cell count, Granulom... OMIM:619802
Immunodeficiency 104
T lymphocytopenia, Splenomegaly, Lymphadenopathy OMIM:608971
Immunodeficiency 13
Lymphopenia, Decreased CD4:CD8 ratio, Decreased proportion of CD4-positive helper T cells, B lymp... OMIM:615518
Pelizaeus-Merzbacher Disease
Mental deterioration, Depression, Failure to thrive, Cerebellar vermis atrophy, Reduction of olig... OMIM:312080
Immunodeficiency 14A With Lymphoproliferation, Autosomal Dominant
Splenomegaly, Decreased proportion of class-switched memory B cells, Increased proportion of tran... OMIM:615513
Polycystic Lipomembranous Osteodysplasia With Sclerosing Leukoencephalopathy 1
Memory impairment, Inappropriate behavior, Lateral ventricle dilatation, Abnormal upper motor neu... OMIM:221770
Immunodeficiency 112
Reduced natural killer cell count, Increased T cell count, Decreased proportion of class-switched... OMIM:620449
Epidermodysplasia Verruciformis, Susceptibility To, 5
Lymphopenia, T lymphocytopenia OMIM:618309
Immunodeficiency 18
Reduced natural killer cell count, Lymphopenia, Abnormal B cell count, Decreased proportion of CD... OMIM:615615
Glycine Encephalopathy 1
Agenesis of corpus callosum, Irritability, Aggressive behavior, Hyperactivity, Restlessness, Impu... OMIM:605899
Neutropenia, Severe Congenital, X-Linked
Monocytopenia, Decreased CD4:CD8 ratio, Neutropenia OMIM:300299
Combined Immunodeficiency Due To Partial Rag1 Deficiency
Splenomegaly, Autoimmune hemolytic anemia, Neutropenia in presence of anti-neutropil antibodies, ... ORPHA:231154
Immunodeficiency 103, Susceptibility To Fungal Infections
Hypereosinophilia, Abnormal B cell count, Abnormal proportion of CD8-positive T cells, Abnormal p... OMIM:212050
Landau-Kleffner Syndrome
EEG with frontal focal spikes, Depression, EEG with generalized epileptiform discharges, Continuo... ORPHA:98818
Cernunnos-Xlf Deficiency
Lymphopenia, Thrombocytopenia, B lymphocytopenia, Anemia, T lymphocytopenia ORPHA:169079
Pick Disease Of Brain
Inappropriate laughter, Disinhibition, Irritability, Polyphagia, Frontotemporal dementia, Gliosis... OMIM:172700
Immunodeficiency 68
Lymphadenitis, Abscess, B lymphocytopenia, Abnormal natural killer cell count, T lymphocytopenia OMIM:612260
Lennox-Gastaut Syndrome
Mental deterioration, Irritability, Aggressive behavior, EEG abnormality, Hyperactivity, EEG with... ORPHA:2382
Immunodeficiency 83, Susceptibility To Viral Infections
Mental deterioration, Herpes simplex encephalitis, Confusion, EEG abnormality, Gliosis OMIM:613002
Progressive Multifocal Leukoencephalopathy
Abnormal astrocyte morphology, Mental deterioration, Cognitive impairment, Abnormal oligodendrogl... ORPHA:217260
T-Cell Immunodeficiency With Thymic Aplasia
Abnormally low T cell receptor excision circle level, Lymphopenia, Hepatosplenomegaly, Aplasia of... OMIM:242700
Cntnap2-Related Developmental And Epileptic Encephalopathy
Abnormal temper tantrums, Mental deterioration, EEG with generalized epileptiform discharges, Cer... ORPHA:163681
Immunodeficiency 80 With Or Without Congenital Cardiomyopathy
Reduced natural killer cell count, Hypoplasia of the thymus, Impaired lymphocyte transformation w... OMIM:619313
Severe Combined Immunodeficiency, X-Linked
Hypoplasia of the thymus, T lymphocytopenia, Impaired lymphocyte transformation with phytohemaggl... OMIM:300400
Immunodeficiency 17
Decreased proportion of CD8-positive T cells, Abnormal B cell morphology, T lymphocytopenia, Auto... OMIM:615607
Juvenile Huntington Disease
Depression, Cerebellar atrophy, Cerebellar vermis atrophy, Irritability, Weight loss, Hyperactivi... ORPHA:248111
Combined Immunodeficiency Due To Zap70 Deficiency
Decreased proportion of CD8-positive T cells, Hepatosplenomegaly, Autoimmune hemolytic anemia, Eo... ORPHA:911
Progressive Supranuclear Palsy
Depression, Memory impairment, Emotional lability, Irritability, Gliosis, Cognitive impairment, D... ORPHA:683
Severe Combined Immunodeficiency Due To Adenosine Deaminase Deficiency
Lymphopenia, T lymphocytopenia, Absence of lymph node germinal center, B lymphocytopenia ORPHA:277
New-Onset Refractory Status Epilepticus
EEG with frontal epileptiform discharges, EEG with generalized epileptiform discharges, Intericta... ORPHA:363558
Rasmussen Subacute Encephalitis
Continuous spike and waves during slow sleep, Memory impairment, Increased theta frequency activi... ORPHA:1929
Immunodeficiency 73B With Defective Neutrophil Chemotaxis And Lymphopenia
Abnormally low T cell receptor excision circle level, Lymphadenitis, Lymphopenia, Hepatosplenomeg... OMIM:618986
Intellectual Developmental Disorder, Autosomal Recessive 75, With Neuropsychiatric Features And Variant Lissencephaly
Self-injurious behavior, EEG with generalized epileptiform discharges, Memory impairment, Inappro... OMIM:619827
Phenylketonuria
Depression, Eczematoid dermatitis, Self-mutilation, Irritability, Aggressive behavior, Attention ... OMIM:261600
Immunodeficiency 57 With Autoinflammation
Perianal abscess, Reduced natural killer cell count, T lymphocytopenia, B lymphocytopenia OMIM:618108
Encephalopathy, Acute, Infection-Induced (Herpes-Specific), Susceptibility To, 8
Confusion, Mental deterioration, EEG abnormality, Herpes simplex encephalitis OMIM:617900
Late Infantile Neuronal Ceroid Lipofuscinosis
Mental deterioration, Cerebellar atrophy, Dementia, Abnormal amplitude of flash visual evoked pot... ORPHA:168491
Immunodeficiency 102
Reduced natural killer cell count, Increased proportion of CD8-positive, alpha-beta TEMRA T cells... OMIM:301082
Angelman Syndrome Due To Imprinting Defect In 15Q11-Q13
Inappropriate laughter, Obesity, Short attention span, Polyphagia, EEG abnormality, Hyperactivity ORPHA:411515
Intellectual Developmental Disorder, X-Linked, Syndromic, Houge Type
Attention deficit hyperactivity disorder, Continuous spike and waves during slow sleep, Hyperacti... OMIM:301008
Severe Combined Immunodeficiency, Autosomal Recessive, T Cell-Negative, B Cell-Negative, Nk Cell-Positive
T lymphocytopenia, B lymphocytopenia OMIM:601457
X-Linked Intellectual Disability-Psychosis-Macroorchidism Syndrome
Abnormal fear-induced behavior, Focal EEG discharges with secondary generalization, Obesity, Irri... ORPHA:3077
Infantile Neuroaxonal Dystrophy
Mental deterioration, Cerebellar atrophy, Aspiration pneumonia, Short attention span, Emotional l... ORPHA:35069
Immunodeficiency 85 And Autoimmunity
Decreased proportion of memory B cells, Reduced natural killer cell count, Lymphopenia, Decreased... OMIM:619510
Neurodevelopmental Disorder With Poor Growth And Behavioral Abnormalities
Cerebellar vermis hypoplasia, Depression, Failure to thrive, Short attention span, Aggressive beh... OMIM:620242
Immunodeficiency 115 With Autoinflammation
Anemia, Decreased proportion of memory T cells, T lymphocytopenia, Splenomegaly OMIM:620632
Symptomatic Form Of Fragile X Syndrome In Female Carriers
Self-injurious behavior, Abnormal temper tantrums, Depression, Recurrent otitis media, Recurrent ... ORPHA:449291
Myoclonic-Astatic Epilepsy
EEG with irregular generalized spike and wave complexes, Abnormal emotion, EEG with polyspike wav... ORPHA:1942
Immunodeficiency 49
Abnormally low T cell receptor excision circle level, Lymphopenia, Eosinophilia, Impaired lymphoc... OMIM:617237
Selective Igm Deficiency
Decreased proportion of transitional B cells, Cutaneous abscess, Decreased proportion of CD8-posi... ORPHA:331235
Combined Immunodeficiency Due To Dock8 Deficiency
T lymphocytopenia, B lymphocytopenia ORPHA:217390
Pitt-Hopkins-Like Syndrome 1
Reduced social reciprocity, Aggressive behavior, Attention deficit hyperactivity disorder, Hypera... OMIM:610042
Skeletal Dysplasia-T-Cell Immunodeficiency-Developmental Delay Syndrome
Decreased proportion of CD8-positive T cells, Lymphopenia, Hypereosinophilia, Decreased proportio... ORPHA:508533
Crigler-Najjar Syndrome
Memory impairment, Cognitive impairment, Infectious encephalitis ORPHA:205
Poliomyelitis
Myelitis, Confusion, Abnormal motor nerve conduction velocity, Irritability, Infectious encephali... ORPHA:2912
Severe Combined Immunodeficiency, Autosomal Recessive, T Cell-Negative, B Cell-Positive, Nk Cell-Negative
Absent natural killer cells, Lymphopenia, Absent peripheral lymph nodes in presence of infection,... OMIM:600802
Immunodeficiency 26 With Or Without Neurologic Abnormalities
T lymphocytopenia, Abnormal natural killer cell morphology, B lymphocytopenia OMIM:615966
Wiskott-Aldrich Syndrome
Decreased mean platelet volume, Decreased proportion of CD8-positive T cells, Lymphopenia, Decrea... OMIM:301000
L-2-Hydroxyglutaric Aciduria
Aplasia/Hypoplasia of the cerebellum, Infectious encephalitis ORPHA:79314
Acute Disseminated Encephalomyelitis
Mental deterioration, Myelitis, Herpes simplex encephalitis, Interictal EEG abnormality, EEG with... ORPHA:83597
Pfapa Syndrome
Weight loss, Arthritis, Infectious encephalitis ORPHA:42642
Immunodeficiency 25
Eosinophilia, T lymphocytopenia, Autoimmune hemolytic anemia OMIM:610163
Aregenerative Anemia
Pancytopenia, Decreased proportion of CD4-positive helper T cells, Abnormal proportion of CD8-pos... ORPHA:101096
Hartnup Disease
EEG abnormality, Skin rash, Emotional lability, Infectious encephalitis ORPHA:2116
Whipple Disease
Uveitis, Depression, Polydipsia, Infectious encephalitis, Myositis, Cachexia, Arthritis, Anorexia... ORPHA:3452
Alexander Disease
Self-injurious behavior, Depression, Failure to thrive, Emotional lability, Agenesis of corpus ca... ORPHA:58
Pgm3-Cdg
Bone marrow hypocellularity, Reduced natural killer cell count, Abnormal CD4:CD8 ratio, Cutaneous... ORPHA:443811
Immunodeficiency By Defective Expression Of Mhc Class Ii
Abnormal CD4:CD8 ratio, Pancytopenia, Decreased proportion of CD4-positive helper T cells, Autoim... ORPHA:572
Immunodeficiency 41 With Lymphoproliferation And Autoimmunity
Decreased proportion of CD4+CD25+ regulatory T cells, Hepatosplenomegaly, Decreased CD4:CD8 ratio... OMIM:606367
Citrullinemia Type Ii
Decreased body mass index, Memory impairment, Confusion, Abnormal eating behavior, Irritability, ... ORPHA:247585
Neurocutaneous Melanocytosis
Chiari malformation, Infectious encephalitis, Aplasia/Hypoplasia of the cerebellum, EEG abnormali... ORPHA:2481
Immunodeficiency 40
T lymphocytopenia, Eosinophilic granuloma, Thrombocytopenia OMIM:616433
Childhood Absence Epilepsy
Depression, EEG with spike-wave complexes (2.5-3.5 Hz), Punding, Attention deficit hyperactivity ... ORPHA:64280
Meningococcal Meningitis
Skin rash, Infectious encephalitis, Irritability, Anorexia ORPHA:33475
Hepatic Veno-Occlusive Disease-Immunodeficiency Syndrome
Decreased proportion of memory B cells, Absence of lymph node germinal center, Hepatosplenomegaly... ORPHA:79124
Nipah Virus Disease
Infectious encephalitis, Anorexia ORPHA:99825
Drug Reaction With Eosinophilia And Systemic Symptoms
Hepatitis, Interstitial pneumonitis, Skin rash, Infectious encephalitis, Pustule, Weight loss, Er... ORPHA:139402
Immunodeficiency 37
Colitis, Infectious encephalitis OMIM:616098
Behçet Disease
Memory impairment, Orchitis, Confusion, Recurrent aphthous stomatitis, Irritability, Increased in... ORPHA:117
Zika Virus Disease
Myelitis, Skin rash, Infectious encephalitis, Arthritis, Conjunctivitis, Maculopapular exanthema ORPHA:448237
Immunodeficiency-Centromeric Instability-Facial Anomalies Syndrome 1
Reduced natural killer cell count, T lymphocytopenia OMIM:242860
T-Cell Immunodeficiency With Thymic Aplasia
Decreased proportion of naive T cells, Aplasia of the thymus, Coombs-positive hemolytic anemia, L... ORPHA:83471
Gm1 Gangliosidosis
Failure to thrive, Aspiration pneumonia, Oral aversion, Infectious encephalitis, Weight loss, Cog... ORPHA:354
Choreoacanthocytosis
Mental deterioration, Lateral ventricle dilatation, Emotional lability, Hair-pulling, Weight loss... ORPHA:2388
Amoebiasis Due To Free-Living Amoebae
Pneumonia, Abnormal medulla oblongata morphology, Confusion, Abnormal cerebellum morphology, Irri... ORPHA:68
Bacterial Toxic-Shock Syndrome
Pneumonia, Hepatitis, Fasciitis, Confusion, Osteomyelitis, Skin rash, Infectious encephalitis, My... ORPHA:36234
Lyme Disease
Infectious encephalitis, Memory impairment, Arthritis, Uveitis ORPHA:91546
Japanese Encephalitis
Decreased motor nerve conduction velocity, EEG with burst suppression, Infectious encephalitis, E... ORPHA:79139
Encephalitis, Acute, Infection (Viral)-Induced, Susceptibility To, 11
Viral encephalitis OMIM:619441
T-B+ Severe Combined Immunodeficiency Due To Jak3 Deficiency
Absent natural killer cells, Lymphopenia, Hepatosplenomegaly, Impaired lymphocyte transformation ... ORPHA:35078
Aspergillosis
Pneumonia, Keratitis, Hepatitis, Osteomyelitis, Infectious encephalitis, Sinusitis, Bronchiectasis ORPHA:1163
Microsporidiosis
Lymphadenitis, Keratoconjunctivitis, Cachexia, Weight loss, Prostatitis, Anorexia, Endocarditis, ... ORPHA:2552
Subacute Sclerosing Panencephalitis
Infectious encephalitis OMIM:260470
Brucellosis
Arteritis, Sacroiliac arthritis, Knee osteoarthritis, Weight loss, Glomerulonephritis, Anorexia, ... ORPHA:1304
Alpha-Thalassemia-X-Linked Intellectual Disability Syndrome
Self-injurious behavior, Infectious encephalitis, Depression, Agenesis of corpus callosum ORPHA:847
Congenital Enterovirus Infection
Hepatitis, Skin rash, Infectious encephalitis, Irritability, Myocarditis ORPHA:292
Ataxia-Telangiectasia
Lymphopenia, Decreased proportion of CD4-positive helper T cells, Abnormal B cell count, T lympho... OMIM:208900
Mhc Class Ii Deficiency 1
Chronic mucocutaneous candidiasis, Failure to thrive, Infectious encephalitis, Colitis, Cholangit... OMIM:209920
Cerebral Visual Impairment
Attention deficit hyperactivity disorder, Short attention span, Infectious encephalitis ORPHA:447788
Legionnaires Disease
Hepatitis, Infectious encephalitis, Pancreatitis, Anorexia, Myocarditis, Endocarditis, Pericarditis ORPHA:549
Vertebral Anomalies And Variable Endocrine And T-Cell Dysfunction
Abnormal B cell morphology, Decreased response to growth hormone stimulation test, Aplasia of the... OMIM:618223
Typhoid
Skin rash, Infectious encephalitis ORPHA:99745
Hemophagocytic Lymphohistiocytosis, Familial, 1
Infectious encephalitis, Failure to thrive, Irritability OMIM:267700
Hemophagocytic Lymphohistiocytosis, Familial, 2
Skin rash, Infectious encephalitis, Failure to thrive, Irritability OMIM:603553
Q Fever
Pneumonia, Hepatitis, Osteomyelitis, Cholecystitis, Infectious encephalitis, Weight loss, Anorexi... ORPHA:781
Cysticercosis
Mental deterioration, Memory impairment, Confusion, Emotional lability, Infectious encephalitis, ... ORPHA:1560
Reynolds Syndrome
Skin rash, Infectious encephalitis, Keratoconjunctivitis sicca, Arthritis, Dysphagia ORPHA:779
Scrub Typhus
Myocarditis, Infectious encephalitis, Skin rash, Anterior uveitis ORPHA:83317
Intellectual Developmental Disorder, Autosomal Dominant 43
Aggressive behavior, Failure to thrive, Hyperactivity, Impulsivity OMIM:616977
Lymphoproliferative Syndrome, X-Linked, 1
Fulminant hepatitis, Infectious encephalitis OMIM:308240
Tmem70-Related Mitochondrial Encephalo-Cardio-Myopathy
Infectious encephalitis ORPHA:1194
Listeriosis
Pneumonia, Arteritis, Osteomyelitis, Pyelonephritis, Cholecystitis, Irritability, Pustule, Infect... ORPHA:533
American Trypanosomiasis
Myocarditis, Skin rash, Infectious encephalitis ORPHA:3386
Avian Influenza
Pneumonia, Myelitis, Hepatitis, Infectious encephalitis, Conjunctivitis ORPHA:454836
Rapid-Onset Childhood Obesity-Hypothalamic Dysfunction-Hypoventilation-Autonomic Dysregulation Syndrome
Self-injurious behavior, Depression, Polydipsia, Obesity, Emotional lability, Reduced social reci... ORPHA:293987
Isolated Growth Hormone Deficiency, Type Iii, With Agammaglobulinemia
Pneumonia, Recurrent otitis media, Pyoderma, Infectious encephalitis, Prostatitis, Enteroviral he... OMIM:307200
Familial Hemophagocytic Lymphohistiocytosis
Skin rash, Infectious encephalitis, Erythroderma, Colitis, Maculopapular exanthema ORPHA:540
Spondyloenchondrodysplasia With Immune Dysregulation
Lymphopenia, T lymphocytopenia, Lymphadenopathy, Neutropenia, Autoimmune thrombocytopenia OMIM:607944
Nocardiosis
Pneumonia, Lymphadenitis, Cutaneous abscess, Keratitis, Osteomyelitis, Infectious encephalitis, S... ORPHA:31204
Incontinentia Pigmenti
Keratitis, Skin rash, Infectious encephalitis, Attention deficit hyperactivity disorder, Cognitiv... ORPHA:464
Progeria-Short Stature-Pigmented Nevi Syndrome
Microcytic anemia, T lymphocytopenia, Neoplasm of the pancreas ORPHA:2959
Autoimmune Lymphoproliferative Syndrome
Lymphopenia, Hypersplenism, Decreased proportion of CD4-positive helper T cells, Autoimmune hemol... ORPHA:3261
Agammaglobulinemia, X-Linked
Lymph node hypoplasia, Neutropenia, B lymphocytopenia, Anemia, T lymphocytopenia OMIM:300755
Zygomycosis
Nephritis, Hepatitis, Fasciitis, Infectious encephalitis, Pustule, Peritonitis, Enterocolitis, Pa... ORPHA:73263
Vici Syndrome
Lymphopenia, Leukopenia, Decreased proportion of CD4-positive helper T cells, Neutropenia, T lymp... OMIM:242840
Chikungunya
Depression, Skin rash, Infectious encephalitis, Crusting erythematous dermatitis, Synovitis, Arth... ORPHA:324625
Immunoglobulin A Vasculitis
Episcleritis, Skin rash, Infectious encephalitis, Pustule, Orchitis, Arthritis, Anorexia ORPHA:761
Rift Valley Fever
Hepatitis, Skin rash, Infectious encephalitis, Anorexia, Uveitis ORPHA:319251
Nijmegen Breakage Syndrome
T lymphocytopenia, Autoimmune hemolytic anemia, Thrombocytopenia, B lymphocytopenia OMIM:251260
Immunodeficiency 82 With Systemic Inflammation
Reduced natural killer cell count, Decreased proportion of naive T cells, Follicular hyperplasia,... OMIM:619381
Autoimmune Enteropathy And Endocrinopathy-Susceptibility To Chronic Infections Syndrome
Inflammatory abnormality of the skin, Eczematoid dermatitis, Chronic mucocutaneous candidiasis, H... ORPHA:391487

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Hivep2

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Hivep2.

No publications found that use IMPC mice or data for Hivep2.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Hivep2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Hivep2tm1e(KOMP)Wtsi Targeted, non-conditional allele ES Cells

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