Genes Phenotypes

Gene: Ikbkb

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Name
inhibitor of kappaB kinase beta
MGI ID
MGI:1338071
Synonyms
IKKbeta IKK[b] IKK-2 IKK-beta IKK2
Viability
Homozygous - Subviable
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (1) Measurements chart (142) All data table (256)
Expression & images (45) Disease models (0) Order (4)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, incomplete penetrance Ikbkbtm1a(EUCOMM)Wtsi HOM Early adult 0.00

Download data as:  TSV  XLS

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (1/2) N/A
Aorta 2 No N/A
Blood vessel 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2) N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Esophagus 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No  (2/2) N/A
Peripheral nervous system 2 No  (2/2) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (2/2) N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle tissue 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No N/A
Testis 2 No  (2/584) N/A
Thymus 2 No  (2/2) N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No  (2/2) N/A
Uterus 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
LacZ Section Images
Ikbkbtm1a(EUCOMM)Wtsi
pituitary gland, peripheral nervous system, HET, Female, WTSI
Ikbkbtm1a(EUCOMM)Wtsi
prostate gland, HET, Male, WTSI
Ikbkbtm1a(EUCOMM)Wtsi
brain, HET, Female, WTSI
Ikbkbtm1a(EUCOMM)Wtsi
parathyroid gland, HET, Female, WTSI
Ikbkbtm1a(EUCOMM)Wtsi
cartilage tissue, HET, Female, WTSI

View all 13 images

Ikbkbtm1a(EUCOMM)Wtsi
prostate gland, HET, Male, WTSI
Ikbkbtm1a(EUCOMM)Wtsi
adrenal gland, HET, Female, WTSI
Ikbkbtm1a(EUCOMM)Wtsi
thymus, HET, Female, WTSI
Ikbkbtm1a(EUCOMM)Wtsi
ovary, HET, Female, WTSI
Ikbkbtm1a(EUCOMM)Wtsi
kidney, HET, Female, WTSI

View all 6 images

Ikbkbtm1a(EUCOMM)Wtsi
pituitary gland, peripheral nervous system, HET, Female, WTSI
Ikbkbtm1a(EUCOMM)Wtsi
brain, HET, Female, WTSI
Ikbkbtm1a(EUCOMM)Wtsi
brain, HET, Female, WTSI
Ikbkbtm1a(EUCOMM)Wtsi
spinal cord, HET, Female, WTSI
Ikbkbtm1a(EUCOMM)Wtsi
parathyroid gland, HET, Female, WTSI
Ikbkbtm1a(EUCOMM)Wtsi
adrenal gland, HET, Female, WTSI
Ikbkbtm1a(EUCOMM)Wtsi
prostate gland, HET, Male, WTSI
Ikbkbtm1a(EUCOMM)Wtsi
ovary, HET, Female, WTSI
Ikbkbtm1a(EUCOMM)Wtsi
lower urinary tract, HET, Female, WTSI
Ikbkbtm1a(EUCOMM)Wtsi
kidney, HET, Female, WTSI
Ikbkbtm1a(EUCOMM)Wtsi
prostate gland, HET, Male, WTSI
Ikbkbtm1a(EUCOMM)Wtsi
thymus, HET, Female, WTSI
Ikbkbtm1a(EUCOMM)Wtsi
cartilage tissue, HET, Female, WTSI
No Embryo expression data was found for this gene.

 Associated Images

Legacy Phenotype Associated Images
Ikbkbtm1a(EUCOMM)Wtsi
head, HET, Female, WTSI
Ikbkbtm1a(EUCOMM)Wtsi
forearm, HET, Female, WTSI
Ikbkbtm1a(EUCOMM)Wtsi
forearm, HET, Female, WTSI
Ikbkbtm1a(EUCOMM)Wtsi
body, HET, Female, WTSI
Ikbkbtm1a(EUCOMM)Wtsi
body, HET, Female, WTSI

View all 98 images

Ikbkbtm1a(EUCOMM)Wtsi
eye, abnormal retinal pigmentation, HET, Male, WTSI
Ikbkbtm1a(EUCOMM)Wtsi
eye, abnormal retinal pigmentation, HET, Male, WTSI
Ikbkbtm1a(EUCOMM)Wtsi
eye, abnormal retinal pigmentation, HET, Male, WTSI
Ikbkbtm1a(EUCOMM)Wtsi
back skin, HET, Female, WTSI

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Ikbkbtm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Ikbkbtm39952(L1L2_gt0_Del_LacZ) Targeting vectors
Ikbkbtm39952(pL1L2_frt15_BetactinBSD_frt14_neo_Rox) Targeting vectors
Ikbkbtm39952(pL1L2_GT0_DelLacZ_bsd) Targeting vectors

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