Itsn1 | intersectin 1 (SH3 domain protein 1A)
Physiological systems
16 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Integument Nervous system Behavior/neurological
12 No significant impact
8 Not tested
Data collections
Gene metrics:10Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
increased circulating amylase level | 1 supporting dataset | Itsn1em1(IMPC)H | homozygote | Early adult | 2.81x10-8 | ||
increased circulating iron level | 1 supporting dataset | Itsn1em1(IMPC)H | homozygote | Early adult | 2.67x10-11 | ||
increased circulating total protein level | 1 supporting dataset | Itsn1em1(IMPC)H | homozygote | Early adult | 2.31x10-5 | ||
abnormal gait | 1 supporting dataset | Itsn1em1(IMPC)H | homozygote | Early adult | 1.26x10-5 | ||
decreased exploration in new environment | 1 supporting dataset | Itsn1em1(IMPC)H | heterozygote | Early adult | 6.08x10-7 | ||
abnormal skin coloration | 2 supporting datasets | Itsn1em1(IMPC)H | homozygote | Early adult | 2.76x10-11 | ||
increased circulating alkaline phosphatase level | 1 supporting dataset | Itsn1em1(IMPC)H | homozygote | Early adult | 2x10-17 | ||
limb grasping | 1 supporting dataset | Itsn1em1(IMPC)H | homozygote | Early adult | 1.04x10-8 | ||
decreased prepulse inhibition | 1 supporting dataset | Itsn1em1(IMPC)H | homozygote | Early adult | 2.57x10-5 | ||
increased circulating serum albumin level | 1 supporting dataset | Itsn1em1(IMPC)H | homozygote | Early adult | 6.26x10-5 |
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External links
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Itsn1em1(IMPC)H | Exon Deletion | | mouse |
Itsn1tm2a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |