Gene: Itgb8

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Itgb8tm1b(KOMP)Wtsi HOM   Early adult 0.00
abnormal eye anterior chamber depth Itgb8tm1b(KOMP)Wtsi HET   Early adult 8.10×10-07
abnormal skin coloration Itgb8tm1b(KOMP)Wtsi HET Early adult 1.97×10-06
decreased spleen weight Itgb8tm1b(KOMP)Wtsi HET Early adult 2.06×10-05
decreased cornea thickness Itgb8tm1b(KOMP)Wtsi HET   Early adult 6.64×10-07

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Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
2 No  (4/583) N/A
2 No  (1/583) N/A
2 No  Wholemount images
2 No  (4/583)  (2/2)  Wholemount images
2 No  (2/583)  (2/2)  Wholemount images
2 No N/A
2 No  (1/583)  Wholemount images
2 No  (3/583) N/A
2 No  (2/583) N/A
2 No  (7/407) N/A
2 No N/A
2 No N/A
2 No  (2/583) N/A
2 No  (3/583) N/A
2 No  (2/583)  (2/2) N/A
2 No  (21/583)  (2/2)  Wholemount images
2 No  (10/583) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (2/583) N/A
2 No  (1/583) N/A
2 No N/A
2 No N/A
2 No  (2/583)  (2/2)  Wholemount images
2 No N/A
2 No  (1/583) N/A
2 No N/A
2 No  (5/583) N/A
2 No  (1/563) N/A
2 No  (2/583)  (2/2)  Wholemount images
2 No N/A
2 No  (1/583) N/A
2 No  (12/583)  (1/2)  Wholemount images
2 No N/A
2 No  (1/583) N/A
2 No  (9/583) N/A
2 No  (3/583)  (1/2)  Wholemount images
2 No  (3/583) N/A
2 No  (13/583) N/A
2 No  (3/583)  (2/2)  Wholemount images
2 No  (6/583)  (1/2)  Wholemount images
2 No  (1/583) N/A
2 No  (17/583)  (2/2)  Wholemount images
2 No  (3/583) N/A
2 No  (2/2)  Wholemount images
2 No N/A
2 No  (1/2)  Wholemount images
2 No  (15/382)  Wholemount images
2 No  (2/2)  Wholemount images
2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (1/60) N/A
2  (1/64)  (2/2) N/A
2  (6/505)  (2/2) N/A
2  (1/73)  (2/2) N/A
2  (1/64)  (2/2) N/A
2  (1/60)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/506)  (2/2) N/A
2  (1/71)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/55)  (2/2) N/A
2  (1/505) N/A
2  (1/302)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/61) N/A
2  (1/59)  (2/2) N/A
2  (1/505) N/A
2  (5/505)  (2/2) N/A
2  (1/60)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/60)  (2/2) N/A
2  (6/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/64)  (2/2) N/A
2  (1/64) N/A
2  (1/58)  (2/2) N/A
2  (1/503) N/A
2  (1/302)  (2/2) N/A
2  (1/503) N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/55)  (1/2) N/A
2  (1/55)  (1/2) N/A
2  (1/55) N/A
2  (1/505)  (2/2) N/A
2  (1/60)  (2/2) N/A
2  (1/75)  (2/2) N/A
2  (1/60)  (2/2) N/A
2  (1/503)  (2/2) N/A
2  (1/60)  (2/2) N/A
2  (1/55) N/A
2  (1/55) N/A
2  (1/56) N/A
2  (1/64)  (2/2) N/A
2  (1/57)  (2/2) N/A
2  (1/75)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/72)  (2/2) N/A
2  (1/55) N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/55)  (2/2) N/A
2  (1/55)  (2/2) N/A
2  (1/59) N/A
2  (1/60)  (2/2) N/A
2  (1/60)  (2/2) N/A
2  (1/60)  (2/2) N/A
2  (1/302)  (2/2) N/A
2  (1/302)  (2/2) N/A
2  (1/59)  (2/2) N/A
2  (1/71) N/A

 Associated Images

X-ray: XRay Images Forepaw
10 Images
Adult LacZ: LacZ Images Wholemount
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
Embryo LacZ: LacZ images wholemount
4 Images
Immunophenotyping: Panel A FCS file(s)
6 Images
Immunophenotyping: Panel B FCS file(s)
6 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Itgb8tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Itgb8tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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