Itgb8 | integrin beta 8

GeneMGI:1338035Synonyms: 4832412O06Rik

Physiological systems

21 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Integument Vision/eye Mortality/aging

18 No significant impact

3 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:50Adult tissues
62Embryo tissues

Phenotypes

abnormal retina outer nuclear layer morphology2 supporting datasetsItgb8tm1b(KOMP)WtsiheterozygoteEarly adult4.73x10-5 
preweaning lethality, complete penetrance3 supporting datasetsItgb8tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
embryonic lethality prior to tooth bud stage1 supporting datasetItgb8tm1b(KOMP)WtsihomozygoteE12.5N/A * 
abnormal skin coloration1 supporting datasetItgb8tm1b(KOMP)WtsiheterozygoteEarly adult3.55x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  

lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Itgb8tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Itgb8tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse

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