Itgb8 | integrin beta 8
Physiological systems
21 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Integument Vision/eye Mortality/aging
18 No significant impact
3 Not tested
Data collections
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:50Adult tissues
62Embryo tissues
abnormal retina outer nuclear layer morphology | 2 supporting datasets | Itgb8tm1b(KOMP)Wtsi | heterozygote | Early adult | 4.73x10-5 | ||
preweaning lethality, complete penetrance | 3 supporting datasets | Itgb8tm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
embryonic lethality prior to tooth bud stage | 1 supporting dataset | Itgb8tm1b(KOMP)Wtsi | homozygote | E12.5 | N/A * | ||
abnormal skin coloration | 1 supporting dataset | Itgb8tm1b(KOMP)Wtsi | heterozygote | Early adult | 3.55x10-6 |
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External links
No external links available for Itgb8.
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Itgb8tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell |
Itgb8tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |