Not currently registered for phenotyping at IMPC
Phenotyping is currently not planned for a knockout strain of this gene.
Gene Summary
IMPC Data Collections
- No Body Weight Data
- No Embryo Imaging Data
- No Viability Data
Phenotyping is currently not planned for a knockout strain of this gene.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases predicted to be associated to Phf2 by phenotypic similarity.
Disease | Similarity of phenotypes |
Matching phenotypes | Source |
---|---|---|---|
Silver-Russell Syndrome Due To 11P15 Microduplication | Short stature, Small for gestational age, Postnatal growth retardation, Severe intrauterine growt... | ORPHA:231144 | |
Mandibuloacral Dysplasia | Loss of subcutaneous adipose tissue in limbs, Alopecia, Lipoatrophy, Increased subcutaneous trunc... | ORPHA:2457 |
The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Phf2.
There are 5 publications which use IMPC produced mice or data.
Title | Journal | IMPC Allele | PubMed ID |
---|---|---|---|
Fine-tuning GPCR-mediated neuromodulation by biasing signaling through different G protein subunits. | Molecular cell (June 2023) | Phf24tm1c(EUCOMM)Hmgu Phf24tm1a(EUCOMM)Hmgu | 37390816 |
Spatiotemporal gene expression patterns reveal molecular relatedness between retinal laminae. | The Journal of comparative neurology (October 2019) | Phf24tm1b(EUCOMM)Hmgu | 31609468 |
Large-scale neuroanatomical study uncovers 198 gene associations in mouse brain morphogenesis. | Nature communications (August 2019) | Phf20tm1a(EUCOMM)Wtsi Phf20tm1a(EUCOMM)Wtsi | PMC6671969 |
Mouse screen reveals multiple new genes underlying mouse and human hearing loss. | PLoS biology (April 2019) | Phf20tm1a(EUCOMM)Wtsi | PMC6459510 |
An efficient method for generation of bi-allelic null mutant mouse embryonic stem cells and its application for investigating epigenetic modifiers. | Nucleic acids research (December 2017) | Phf20tm1a(EUCOMM)Wtsi | PMC5716182 |
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
MGI Allele | Allele Type | Produced |
---|---|---|
Phf2tm267868(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | Targeting vectors |
Get highlights of the most important data releases, news and events, delivered straight to your email inbox
Subscribe to newsletter