Genes Phenotypes

Gene: Eya4

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Name
EYA transcriptional coactivator and phosphatase 4
MGI ID
MGI:1337104
Synonyms
B130023L16Rik
Viability
Homozygous - Lethal
Embryo viewer
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (6) Measurements chart (223) All data table (690)
Expression & images (71) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
edema Eya4tm1b(KOMP)Wtsi HET E15.5 0.00
edema Eya4tm1b(KOMP)Wtsi HOM E15.5 0.00
increased or absent threshold for auditory brainstem response Eya4tm1b(KOMP)Wtsi HET Early adult 1.56×10-08
small adrenal glands Eya4tm1b(KOMP)Wtsi HET Early adult 0.00
abnormal embryo size Eya4tm1b(KOMP)Wtsi HOM E15.5 0.00
preweaning lethality, complete penetrance Eya4tm1b(KOMP)Wtsi HOM Early adult 0.00

Download data as:  TSV  XLS

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Bone 1 No  Section images
Brain 2 No N/A
Brainstem 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (1/2) N/A
Large intestine 2 No  (10/584)  (1/2) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584)  (1/2)  Section images
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2)  Section images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584)  (2/2)  Section images
Trachea 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
endocrine system (2)
Thyroid gland expression
MA:0000129
exocrine system (1)
Prostate gland expression
MA:0000404
musculoskeletal system (2)
Bone no expression
MA:0001459
postnatal mouse (7)
Bone no expression
MA:0001459
reproductive system (3)
Prostate gland expression
MA:0000404
trunk (3)
Prostate gland expression
MA:0000404
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 3  (1/61)  (3/3) N/A
Brain 3  (6/504) N/A
Central nervous system ganglion 3  (1/70) N/A
Ear 3  (1/504) N/A
Embryo 3  (1/505)  (3/5) N/A
Eye 3  (1/504) N/A
Foot 3  (1/504)  (3/5) N/A
Forebrain 3  (1/504) N/A
Forelimb 3  (1/504)  (3/5) N/A
Gut 3  (1/56) N/A
Hand 3  (1/503)  (3/5) N/A
Head 3  (5/504) N/A
Heart 3  (1/504) N/A
Hindbrain 3  (6/504) N/A
Hindlimb 3  (1/503)  (3/5) N/A
Liver 3  (1/504) N/A
Lung 3  (1/500) N/A
Mandibular process 3  (1/504)  (3/5) N/A
Maxillary process 3  (1/504)  (3/5) N/A
Midbrain 3  (1/504) N/A
Nose 3  (1/70)  (3/3) N/A
Oral cavity 3  (1/504) N/A
Skeleton 3  (1/70)  (3/3) N/A
Skin 3  (1/504) N/A
Spinal cord 3  (1/69) N/A
Tail 3  (1/504)  (3/5) N/A
Tail somite 3  (1/504) N/A
Trachea 3  (1/56) N/A
Urinary system 3  (1/56) N/A

 Associated Images

Adult LacZ: LacZ Images Section
7 Images
X-ray: XRay Images Whole Body Dorso Ventral
14 Images
X-ray: XRay Images Hind Leg and Hip
14 Images
X-ray: XRay Images Whole Body Lateral Orientation
28 Images
Embryo LacZ: LacZ images wholemount
46 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images
Gross Pathology and Tissue Collection
9 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Eya4tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Eya4tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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