Eya4 | EYA transcriptional coactivator and phosphatase 4

GeneMGI:1337104Synonyms: B130023L16Rik

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Endocrine/exocrine gland Embryo Growth/size/body region Mortality/aging

15 No significant impact

4 Not tested

Gene metrics:4Significant phenotypes
4Associated diseases
Expression examined in:42Adult tissues
50Embryo tissues

Phenotypes

preweaning lethality, complete penetrance3 supporting datasetsEya4tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
small adrenal glands1 supporting datasetEya4tm1b(KOMP)WtsiheterozygoteEarly adultN/A * 
edema1 supporting datasetEya4tm1b(KOMP)WtsiheterozygoteE15.5N/A * 
edema1 supporting datasetEya4tm1b(KOMP)WtsihomozygoteE15.5N/A * 
abnormal embryo size1 supporting datasetEya4tm1b(KOMP)WtsihomozygoteE15.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Eya4tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Eya4tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Eya4tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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