Genes Phenotypes

Gene: Eya4

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Name
EYA transcriptional coactivator and phosphatase 4
MGI ID
MGI:1337104
Synonyms
B130023L16Rik
Viability
Homozygous - Lethal
Embryo viewer
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (6) Measurements chart (223) All data table (690)
Expression & images (71) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
edema Eya4tm1b(KOMP)Wtsi HOM E15.5 0.00
increased or absent threshold for auditory brainstem response Eya4tm1b(KOMP)Wtsi HET Early adult 1.56×10-08
edema Eya4tm1b(KOMP)Wtsi HET E15.5 0.00
small adrenal glands Eya4tm1b(KOMP)Wtsi HET Early adult 0.00
preweaning lethality, complete penetrance Eya4tm1b(KOMP)Wtsi HOM Early adult 0.00
abnormal embryo size Eya4tm1b(KOMP)Wtsi HOM E15.5 0.00

Download data as:  TSV  XLS

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Bone 1 No  Section images
Brain 2 No N/A
Brainstem 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (1/2) N/A
Large intestine 2 No  (10/584)  (1/2) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584)  (1/2)  Section images
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2)  Section images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584)  (2/2)  Section images
Trachea 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
endocrine system (2)
Thyroid gland expression
MA:0000129
exocrine system (1)
Prostate gland expression
MA:0000404
musculoskeletal system (2)
Bone no expression
MA:0001459
postnatal mouse (7)
Bone no expression
MA:0001459
reproductive system (3)
Prostate gland expression
MA:0000404
trunk (3)
Prostate gland expression
MA:0000404
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 3  (1/61)  (3/3) N/A
Brain 3  (6/504) N/A
Central nervous system ganglion 3  (1/70) N/A
Ear 3  (1/504) N/A
Embryo 3  (1/505)  (3/5) N/A
Eye 3  (1/504) N/A
Foot 3  (1/504)  (3/5) N/A
Forebrain 3  (1/504) N/A
Forelimb 3  (1/504)  (3/5) N/A
Gut 3  (1/56) N/A
Hand 3  (1/503)  (3/5) N/A
Head 3  (5/504) N/A
Heart 3  (1/504) N/A
Hindbrain 3  (6/504) N/A
Hindlimb 3  (1/503)  (3/5) N/A
Liver 3  (1/504) N/A
Lung 3  (1/500) N/A
Mandibular process 3  (1/504)  (3/5) N/A
Maxillary process 3  (1/504)  (3/5) N/A
Midbrain 3  (1/504) N/A
Nose 3  (1/70)  (3/3) N/A
Oral cavity 3  (1/504) N/A
Skeleton 3  (1/70)  (3/3) N/A
Skin 3  (1/504) N/A
Spinal cord 3  (1/69) N/A
Tail 3  (1/504)  (3/5) N/A
Tail somite 3  (1/504) N/A
Trachea 3  (1/56) N/A
Urinary system 3  (1/56) N/A

 Associated Images

Adult LacZ: LacZ Images Section
7 Images
X-ray: XRay Images Whole Body Lateral Orientation
28 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images
X-ray: XRay Images Whole Body Dorso Ventral
14 Images
X-ray: XRay Images Hind Leg and Hip
14 Images
Gross Pathology and Tissue Collection
9 Images
Embryo LacZ: LacZ images wholemount
46 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Eya4tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Eya4tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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