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Gene: Ap3s1

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Name adaptor-related protein complex 3, sigma 1 subunit

Synonyms [s]3A

Status ES CellsMice
tm1aMice
tm1bphenotype data available

Links MGI:1337062   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Viable

Phenotype associations for Ap3s1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Ap3s1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
increased or absent threshold for auditory brainstem response Ap3s1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 2.0E-7
increased fasted circulating glucose level Ap3s1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 6.93E-7
increased heart rate Ap3s1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 4.44E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393)
Aorta 2 No (1/562)
Blood 2 No
Bone 2 No (1/539)
Bone marrow 2 No
Brain 2 No (6/562) (2/2)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562)
Cecum 2 No (1/355)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Chest bone 2 No
Colon 2 No (1/99)
Cranium 2 No
Diaphragm 2 No
Epididymis 2 No (4/106)
Esophagus 2 No (2/393)
Eye 2 No (1/562)
Gall bladder 2 No
Harderian gland 2 No
Heart 2 No (3/562)
Hindlimb 2 No
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (20/562)
Large intestine 2 No (12/562)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562)
Lymph node 2 No (1/562)
Main olfactory bulb 2 No
Mammary gland 2 No
Mesenteric lymph node 2 No
Olfactory lobe 2 No (4/393)
Oral epithelium 2 No
Ovary 2 No (1/562) (1/2)
Oviduct 2 No (2/562)
Pancreas 2 No (6/562) (2/2)
Parathyroid gland 2 No (2/540)
Parotid gland 2 No
Penis 2 No
Peripheral nervous system 2 No (3/562)
Peyer's patch 2 No (1/393)
Pituitary gland 2 No (1/562) (1/2)
Prostate gland 2 No (5/562)
Sciatic nerve 2 No
Skeletal muscle 2 No
Skin 2 No (1/562) (2/2)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562)
Spleen 2 No (4/562)
Stomach 2 No (9/562) (2/2)
Stomach pyloric region 2 No
Striatum 2 No (4/562)
Sublingual gland 2 No
Submandibular gland 2 No (1/104) (2/2)
Testis 2 No (4/562) (1/2)
Thymus 2 No (2/2)
Thyroid gland 2 No (16/562)
Tongue 2 No
Trachea 2 No (3/562)
Trigeminal V nerve 2 No
Urinary bladder 2 No (1/2)
Uterus 2 No (2/562) (1/2)
Vagina 2 No
Vas deferens 2 No (1/360)
Vascular system 2 No (1/393)
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    respiratory system
    digestive system
    nervous system
    reproductive system
    immune system
    exocrine system
    integumental system
    trunk
    urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • Adult LacZ: LacZ Images Wholemount
    17 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Ap3s1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Ap3s1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre)
Vector
Gene