Gene: Ap3s2

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adaptor-related protein complex 3, sigma 2 subunit
[s]3B sigma 3B
Embryo viewer
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Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased circulating fructosamine level Ap3s2tm1b(EUCOMM)Hmgu HOM Early adult 5.26×10-06
increased circulating aspartate transaminase level Ap3s2tm1b(EUCOMM)Hmgu HOM Early adult 1.02×10-05

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Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes


IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No  (2/584)  (4/4)  Wholemount images
Aorta 4 No  (4/4)  Wholemount images
Bone 4 No  (4/4)  Wholemount images
Brain 4 No  (4/4)  Wholemount images
Brainstem 4 No  (4/4)  Wholemount images
Brown adipose tissue 4 No N/A
Cartilage tissue 4 No  (4/4)  Wholemount images
Cerebellum 4 No  (4/4)  Wholemount images
Cerebral cortex 4 No  (4/4)  Wholemount images
Esophagus 4 No  (7/415)  (4/4)  Wholemount images
Eye 4 No  (4/4)  Wholemount images
Gall bladder 4 No  (3/4)  Wholemount images
Heart 4 No  (4/4)  Wholemount images
Hippocampus 4 No  (4/4)  Wholemount images
Hypothalamus 4 No  (4/4)  Wholemount images
Kidney 4 No  (18/584)  (4/4)  Wholemount images
Large intestine 4 No  (10/584)  (4/4)  Wholemount images
Liver 4 No N/A
Lower urinary tract 4 No  (4/4)  Wholemount images
Lung 4 No  (4/4)  Wholemount images
Lymph node 4 No N/A
Mammary gland 4 No N/A
Olfactory lobe 4 No  (4/4)  Wholemount images
Oral epithelium 4 No N/A
Ovary 4 No  (1/584)  (2/4)  Wholemount images
Oviduct 4 No  (2/4)  Wholemount images
Pancreas 4 No  (5/584)  (4/4)  Wholemount images
Parathyroid gland 4 No  (4/4)  Wholemount images
Peripheral nervous system 4 No  (4/4)  Wholemount images
Peyer's patch 4 No N/A
Pituitary gland 4 No  (4/4)  Wholemount images
Prostate gland 4 No  (12/584)  (2/4)  Wholemount images
Skeletal muscle 4 No N/A
Skin 4 No  (4/4)  Wholemount images
Small intestine 4 No  (9/584)  (3/4)  Wholemount images
Spinal cord 4 No  (4/4)  Wholemount images
Spleen 4 No  (2/584) N/A
Stomach 4 No  (12/584)  (4/4)  Wholemount images
Striatum 4 No  (4/4)  Wholemount images
Testis 4 No  (2/584)  (2/4) N/A
Thymus 4 No N/A
Thyroid gland 4 No  (15/584)  (4/4) N/A
Trachea 4 No  (3/4)  Wholemount images
Uterus 4 No  (2/4)  Wholemount images
Vascular system 4 No  (4/4)  Wholemount images
White adipose tissue 4 No N/A
No Embryo expression data was found for this gene.

 Associated Images

Echo: M-Mode Images
36 Images
Adult LacZ: LacZ Images Wholemount
22 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Ap3s2tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Ap3s2tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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