Ap4e1 | adaptor-related protein complex AP-4, epsilon 1
Physiological systems
24 / 24 physiological systems tested
17 Significantly impacted by the knock-out
Vision/eye Muscle Nervous system Behavior/neurological Mortality/aging Reproductive system Integument Immune system Homeostasis/metabolism Adipose tissue Skeleton Hematopoietic system Respiratory system Endocrine/exocrine gland Renal/urinary system Cardiovascular system Growth/size/body region
7 No significant impact
Gene metrics:74Significant phenotypes
3Associated diseases
Expression examined in:158Adult tissues
59Embryo tissues
Human diseases caused by Ap4e1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
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