Ap4e1 | adaptor-related protein complex AP-4, epsilon 1
Physiological systems
24 / 24 physiological systems tested
17 Significantly impacted by the knock-out
Reproductive system Immune system Endocrine/exocrine gland Integument Adipose tissue Growth/size/body region Muscle Hematopoietic system Cardiovascular system Renal/urinary system Homeostasis/metabolism Nervous system Vision/eye Respiratory system Behavior/neurological Skeleton Mortality/aging
7 No significant impact
Gene metrics:76Significant phenotypes
3Associated diseases
Expression examined in:158Adult tissues
59Embryo tissues
Human diseases caused by Ap4e1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
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