Genes Phenotypes

Gene: Slc22a8

Log in to follow

Name
solute carrier family 22 (organic anion transporter), member 8
MGI ID
MGI:1336187
Synonyms
Roct OAT3 mOat3
Viability
Homozygous - Viable
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (4) Measurements chart (231) All data table (423)
Expression & images (67) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal circulating HDL cholesterol level Slc22a8tm1b(KOMP)Wtsi HOM Early adult 5.23×10-06
abnormal circulating creatinine level Slc22a8tm1b(KOMP)Wtsi HOM Early adult 2.04×10-05
decreased heart weight Slc22a8tm1b(KOMP)Wtsi HOM Early adult 2.23×10-05
abnormal bone mineral density Slc22a8tm1b(KOMP)Wtsi HOM Early adult 1.83×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/589) N/A
Aorta 2 No  (1/589) N/A
Bone 2 No N/A
Brain 2 No  (3/589) N/A
Brainstem 2 No  (2/589) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (3/589) N/A
Cerebral cortex 2 No  (2/589) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (1/589) N/A
Hippocampus 2 No  (3/589) N/A
Hypothalamus 2 No  (2/589) N/A
Kidney 2 No  (20/589) N/A
Large intestine 2 No  (10/589) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/589) N/A
Lung 2 No  (1/589) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/589) N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/589) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/589) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No  (1/589) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/589) N/A
Prostate gland 2 No  (12/589) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/589) N/A
Spinal cord 2 No  (2/589) N/A
Spleen 2 No  (2/589) N/A
Stomach 2 No  (13/589) N/A
Striatum 2 No  (3/589) N/A
Testis 2 No  (5/589) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (16/589)  (1/2) N/A
Trachea 2 No  (2/589) N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1  (6/506) N/A
Ear 1  (1/506) N/A
Embryo 1  (1/507) N/A
Eye 1  (1/506) N/A
Foot 1  (1/506) N/A
Forebrain 1  (1/506) N/A
Forelimb 1  (1/506) N/A
Hand 1  (1/505) N/A
Head 1  (5/506) N/A
Heart 1  (1/506) N/A
Hindbrain 1  (6/506) N/A
Hindlimb 1  (1/505) N/A
Liver 1  (1/506) N/A
Lung 1  (1/502) N/A
Mandibular process 1  (1/506) N/A
Maxillary process 1  (1/506) N/A
Midbrain 1  (1/506) N/A
Oral cavity 1  (1/506) N/A
Skin 1  (1/506) N/A
Tail 1  (1/506) N/A
Tail somite 1  (1/506) N/A

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
11 Images
X-ray: XRay Images Whole Body Dorso Ventral
11 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
11 Images
Echo: M-Mode Images
32 Images
Embryo LacZ: LacZ images wholemount
8 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

This service may be affected by the Covid-19 pandemic. See how

MGI Allele Allele Type Produced
Slc22a8tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Slc22a8tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Slc22a8tm2a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter