Genes Phenotypes

Gene: Slc22a8

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Name
solute carrier family 22 (organic anion transporter), member 8
MGI ID
MGI:1336187
Synonyms
Roct OAT3 mOat3
Viability
Homozygous - Viable
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (4) Measurements chart (231) All data table (424)
Expression & images (67) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating HDL cholesterol level Slc22a8tm1b(KOMP)Wtsi HOM Early adult 4.82×10-06
decreased bone mineral density Slc22a8tm1b(KOMP)Wtsi HOM Early adult 1.77×10-05
increased circulating creatinine level Slc22a8tm1b(KOMP)Wtsi HOM Early adult 2.04×10-05
decreased heart weight Slc22a8tm1b(KOMP)Wtsi HOM Early adult 2.46×10-05

Download data as:  TSV  XLS

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
2 No  (3/590) N/A
2 No  (1/590) N/A
2 No N/A
2 No  (3/590) N/A
2 No  (2/590) N/A
2 No N/A
2 No N/A
2 No  (3/590) N/A
2 No  (2/590) N/A
2 No  (7/415) N/A
2 No N/A
2 No N/A
2 No  (1/590) N/A
2 No  (3/590) N/A
2 No  (2/590) N/A
2 No  (20/590) N/A
2 No  (10/590) N/A
2 No N/A
2 No  (1/590) N/A
2 No  (1/590) N/A
2 No N/A
2 No N/A
2 No  (2/590) N/A
2 No N/A
2 No  (1/590) N/A
2 No N/A
2 No  (5/590) N/A
2 No N/A
2 No  (1/590) N/A
2 No N/A
2 No  (1/590) N/A
2 No  (12/590) N/A
2 No N/A
2 No N/A
2 No  (9/590) N/A
2 No  (2/590) N/A
2 No  (2/590) N/A
2 No  (13/590) N/A
2 No  (3/590) N/A
2 No  (5/590) N/A
2 No N/A
2 No  (16/590)  (1/2)  Wholemount images
2 No  (2/590) N/A
2 No N/A
2 No N/A
2 No N/A
LacZ Wholemount Images
Unassigned Top Level MA (1)
Thyroid gland expression
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
1  (6/506) N/A
1  (1/506) N/A
1  (1/507) N/A
1  (1/506) N/A
1  (1/506) N/A
1  (1/506) N/A
1  (1/506) N/A
1  (1/506) N/A
1  (5/506) N/A
1  (1/506) N/A
1  (6/506) N/A
1  (1/506) N/A
1  (1/504) N/A
1  (1/504) N/A
1  (1/506) N/A
1  (1/506) N/A
1  (1/506) N/A
1  (1/504) N/A
1  (1/506) N/A
1  (1/506) N/A
1  (1/506) N/A

 Associated Images

Echo: M-Mode Images
31 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
11 Images
Embryo LacZ: LacZ images wholemount
8 Images
X-ray: XRay Images Whole Body Dorso Ventral
11 Images
Adult LacZ: LacZ Images Wholemount
1 Images
X-ray: XRay Images Whole Body Lateral Orientation
11 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Slc22a8tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Slc22a8tm2a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Slc22a8tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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