Gene: Prkaa2

Log in to follow

Name
protein kinase, AMP-activated, alpha 2 catalytic subunit
MGI ID
MGI:1336173
Synonyms
AMPKalpha2 2310008I11Rik
View
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased monocyte cell number Prkaa2tm1b(EUCOMM)Hmgu HOM postnatal 1.03×10-05
decreased fasted circulating glucose level Prkaa2tm1b(EUCOMM)Hmgu HOM postnatal 5.26×10-08
decreased circulating amylase level Prkaa2tm1b(EUCOMM)Hmgu HOM postnatal 2.82×10-05
enlarged spleen Prkaa2tm1b(EUCOMM)Hmgu HOM postnatal 0.00
decreased mean platelet volume Prkaa2tm1b(EUCOMM)Hmgu HOM postnatal 8.37×10-06
increased mean platelet volume Prkaa2tm1b(EUCOMM)Hmgu HOM postnatal 8.37×10-06

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No  (2/2)  Wholemount images
Esophagus 2 No  (7/415)  (1/2)  Wholemount images
Eye 2 No  (1/2)  Wholemount images
Gall bladder 2 No N/A
Heart 2 No  (2/2)  Wholemount images
Hippocampus 2 No  (2/2)  Wholemount images
Hypothalamus 2 No  (2/2)  Wholemount images
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584)  (2/2)  Wholemount images
Liver 2 No N/A
Lower urinary tract 2 No  (2/2)  Wholemount images
Lung 2 No  (2/2)  Wholemount images
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/584)  (1/2)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584)  (2/2)  Wholemount images
Spinal cord 2 No  (2/2)  Wholemount images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2)  Wholemount images
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Uterus 2 No N/A
Vascular system 2 No  (2/2)  Wholemount images
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485) N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485)  (4/4) N/A
Eye 2  (1/485) N/A
Foot 2  (1/485) N/A
Forebrain 2  (1/485) N/A
Forelimb 2  (1/485) N/A
Hand 2  (1/485) N/A
Head 2  (5/485) N/A
Heart 2  (1/485)  (4/4) N/A
Hindbrain 2  (6/485) N/A
Hindlimb 2  (1/485) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485) N/A
Mandibular process 2  (1/485) N/A
Maxillary process 2  (1/485) N/A
Midbrain 2  (1/485) N/A
Oral cavity 2  (1/485) N/A
Skin 2  (1/485) N/A
Tail 2  (1/485) N/A
Tail somite 2  (1/485) N/A

 Associated Images

X-ray: XRay Images Lateral Orientation
10 Images
X-ray: XRay Images Dorso Ventral
10 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Embryo LacZ: LacZ images wholemount
8 Images
Adult LacZ: LacZ Images Wholemount
15 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Skeletal muscle - process of degenerative change Prkaa2tm1b(EUCOMM)Hmgu HOM postnatal
Femur - process of degenerative change Prkaa2tm1b(EUCOMM)Hmgu HOM postnatal
Skin - process of degenerative change Prkaa2tm1b(EUCOMM)Hmgu HOM postnatal

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Prkaa2tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Prkaa2tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter