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Gene: Klrc2 MGI:1336162

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Gene Summary

Name:
killer cell lectin-like receptor subfamily C, member 2
Synonyms:
NKG2C

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IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

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Viewing: all phenotypes
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lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Klrc2 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

The table below shows human diseases associated to Klrc2 by orthology or direct annotation.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Behçet Disease
ORPHA:117

The table below shows human diseases predicted to be associated to Klrc2 by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Behçet Disease
ORPHA:117

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Klrc2

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Klrc2.

There are 2 publications which use IMPC produced mice or data.

Title Journal IMPC Allele PubMed ID
A Genome-Wide Screen in Mice To Identify Cell-Extrinsic Regulators of Pulmonary Metastatic Colonisation. G3 (Bethesda, Md.) (June 2020) Klrc1, Klrc2, Klrc3)em1(IMPC)Wtsi Klrc2em1(IMPC)Wtsi PMC7263671
Large-scale neuroanatomical study uncovers 198 gene associations in mouse brain morphogenesis. Nature communications (August 2019) (Klrc1, Klrc2, Klrc3)em1(IMPC)Wtsi (Klrc1, Klrc2, Klrc3)em1(IMPC)Wtsi Klrc2em1(IMPC)Wtsi PMC6671969

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MGI Allele Allele Type Produced
Klrc2em1(IMPC)Wtsi Deletion Mice

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