Lig4 | ligase IV, DNA, ATP-dependent
Physiological systems
24 / 24 physiological systems tested
11 Significantly impacted by the knock-out
Vision/eye Mortality/aging Reproductive system Immune system Skeleton Embryo Hematopoietic system Endocrine/exocrine gland Renal/urinary system Cardiovascular system Growth/size/body region
13 No significant impact
Data collections
Gene metrics:18Significant phenotypes
5Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
Human diseases caused by Lig4 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
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