Lig4 | ligase IV, DNA, ATP-dependent
Physiological systems
7 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Hematopoietic system Renal/urinary system
1 No significant impact
17 Not tested
Data collections
Gene metrics:7Significant phenotypes
5Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
Human diseases caused by Lig4 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
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