Aspm - abnormal spindle microtubule assembly | International Mouse Phenotyping Consortium

Genes Phenotypes

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Gene: Aspm

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Name

abnormal spindle microtubule assembly

MGI ID

MGI:1334448

Synonyms

Aspm MCPH5 Sha1 D330028K02Rik Calmbp1

Viability

Homozygous - Viable

Embryo viewer

N/A

Other links

MGI Ensembl

Significant phenotypes (6) Measurements chart (277) All data table (331)

Expression & images (0) Disease models (0) Order (1)

Significant

Not Significant

Not tested

View body weight measurements

Phenotype	System	Allele	Zyg	Sex	Life Stage	P Value
increased circulating HDL cholesterol level		Aspm^{tm1a(KOMP)Wtsi}	HOM		Early adult	1.01×10^-05
increased or absent threshold for auditory brainstem response		Aspm^{tm1a(KOMP)Wtsi}	HOM		Early adult	1.89×10^-05
decreased T cell number		Aspm^{tm1a(KOMP)Wtsi}	HOM		Early adult	3.21×10^-05
increased circulating cholesterol level		Aspm^{tm1a(KOMP)Wtsi}	HOM		Early adult	2.41×10^-07
thrombocytopenia		Aspm^{tm1a(KOMP)Wtsi}	HOM		Early adult	1.17×10^-06
increased total body fat amount		Aspm^{tm1a(KOMP)Wtsi}	HOM		Early adult	9.90×10^-05

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Viewing: all phenotypes

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Viewing: all phenotypes

Expression

Expression data not available

Associated Images

Brain Histopathology: Cerebellar Section
3 Images

Brain Histopathology: Striatal Section
3 Images

Brain Histopathology: Hippocampal section
3 Images

X-ray: XRay Images Whole Body Dorso Ventral
41 Images

X-ray: XRay Images Whole Body Lateral Orientation
27 Images

X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images

X-ray: XRay Images Skull Lateral Orientation
14 Images

X-ray: XRay Images Forepaw
13 Images

Legacy Phenotype Associated Images

Aspm^{tm1a(KOMP)Wtsi}
HOM, Female, WTSI

Aspm^{tm1a(KOMP)Wtsi}
HOM, Female, WTSI

Aspm^{tm1a(KOMP)Wtsi}
HOM, Female, WTSI

Aspm^{tm1a(KOMP)Wtsi}
HOM, Female, WTSI

Aspm^{tm1a(KOMP)Wtsi}
HOM, Male, WTSI

View all 105 images

Aspm^{tm1a(KOMP)Wtsi}
corpus callosum, decreased corpus callosum size, HOM, Male, WTSI

Aspm^{tm1a(KOMP)Wtsi}
decreased corpus callosum size, HOM, Male, WTSI

Aspm^{tm1a(KOMP)Wtsi}
WT, Male, WTSI

Aspm^{tm1a(KOMP)Wtsi}
HOM, Male, WTSI

Aspm^{tm1a(KOMP)Wtsi}
HOM, Male, WTSI

View all 15 images

Aspm^{tm1a(KOMP)Wtsi}
back skin, HOM, Female, WTSI

Disease Models

By Annotation and Orthology (0)
By phenotypic Similarity (0)

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MGI Allele	Allele Type	Produced
Aspm^{tm1a(KOMP)Wtsi}	KO first allele (reporter-tagged insertion with conditional potential)	Mice, Targeting vectors, ES Cells

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