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Genes Phenotypes

Gene: Mrpl22

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Name
mitochondrial ribosomal protein L22
MGI ID
MGI:1333794
Synonyms
MRP-L25 HSPC158 Rpml25 E030011D16Rik
Viability
Homozygous - Lethal
Embryo viewer
N/A
Other links
MGI   Ensembl   Early Embryo Phenotypes  
Significant phenotypes (5) Measurements chart (119) All data table (302)
Expression & images (73) Disease models (0) Order (4)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal behavior Mrpl22tm1b(KOMP)Mbp HET Early adult 6.94×10-05
embryonic lethality prior to organogenesis Mrpl22tm1b(KOMP)Mbp HOM   E9.5 0.00
decreased thigmotaxis Mrpl22tm1b(KOMP)Mbp HET Early adult 6.94×10-05
preweaning lethality, complete penetrance Mrpl22tm1b(KOMP)Mbp HOM   Early adult 0.00
impaired pupillary reflex Mrpl22tm1b(KOMP)Mbp HET Early adult 1.41×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/590)  (2/2)  Section images
Aorta 2 No  (1/590)  (2/2)  Section images
Brain 2 No  (3/590)  (2/2)  Section images
Brainstem 2 No  (2/590)  (2/2)  Section images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2)  Section images
Cerebellum 2 No  (3/590)  (2/2)  Section images
Cerebral cortex 2 No  (2/590)  (2/2)  Section images
Epididymis 2 No  (18/134)  (1/2)  Section images
Esophagus 2 No  (7/415)  (2/2)  Section images
Eye 2 No  (2/2)  Section images
Heart 2 No  (1/590)  (2/2)  Section images
Hippocampus 2 No  (3/590)  (2/2)  Section images
Hypothalamus 2 No  (2/590)  (2/2)  Section images
Kidney 2 No  (20/590)  (2/2)  Section images
Large intestine 2 No  (10/590)  (2/2)  Section images
Liver 2 No  (2/2)  Section images
Lower urinary tract 2 No  (1/590) N/A
Lung 2 No  (1/590)  (2/2)  Section images
Lymph node 2 No N/A
Mammary gland 2 No N/A
Midbrain 2 No  (2/2)  Section images
Olfactory lobe 2 No  (2/590)  (2/2)  Section images
Ovary 2 No  (1/590)  Section images
Oviduct 2 No  (1/2)  Section images
Pancreas 2 No  (5/590)  (2/2)  Section images
Peripheral nervous system 2 No  (1/590)  (2/2)  Section images
Peyer's patch 2 No  Section images
Pituitary gland 2 No  (1/590)  (2/2)  Section images
Prostate gland 2 No  (12/590) N/A
Skeletal muscle 2 No  (2/2)  Section images
Skin 2 No  (2/2)  Section images
Small intestine 2 No  (9/590)  (2/2)  Section images
Spinal cord 2 No  (2/590)  (2/2)  Section images
Spleen 2 No  (2/590)  (2/2)  Section images
Stomach 2 No  (13/590)  (2/2)  Section images
Striatum 2 No  (3/590)  (2/2)  Section images
Submandibular gland 2 No  (2/132)  Section images
Testis 2 No  (5/590)  (1/2)  Section images
Thalamus 2 No  (2/2)  Section images
Thymus 2 No N/A
Thyroid gland 2 No  (16/590)  (2/2)  Section images
Trachea 2 No  (2/590) N/A
Urinary bladder 2 No  (2/2)  Section images
Uterus 2 No  (1/2)  Section images
Vascular system 2 No  (2/2)  Section images
Vesicular gland 2 No N/A
White adipose tissue 2 No  (2/2)  Section images
LacZ Wholemount Images
LacZ Section Images
adipose tissue (1)
White Adipose Tissue expression
MA:0000058
cardiovascular system (3)
Aorta expression
MA:0000062
digestive system (7)
Esophagus expression
MA:0000352
endocrine system (2)
Adrenal gland expression
MA:0000116
exocrine system (1)
Submandibular Gland imageOnly
MA:0001589
immune system (2)
Peyers Patch imageOnly
MA:0000137
integumental system (1)
Skin expression
MA:0000151
musculoskeletal system (1)
Skeletal Muscle expression
MA:0003148
nervous system (13)
Brain expression
MA:0000168
postnatal mouse (40)
Adrenal gland expression
MA:0000116
reproductive system (5)
Epididymis expression
MA:0000397
respiratory system (2)
Lung expression
MA:0000415
sensory organ (1)
Eye expression
MA:0000261
set of connective tissues (2)
Cartilage tissue expression
MA:0000104
trunk (20)
Adrenal gland expression
MA:0000116
urinary system (2)
Kidney expression
MA:0000368
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/506)  (1/2) N/A
Dorsal root ganglion 2  (1/61) Image Only N/A
Ear 2  (1/506) N/A
Embryo 2  (1/507)  (2/2)  Wholemount images
Eye 2  (1/506)  (2/2) N/A
Foot 2  (1/506)  (2/2) N/A
Forebrain 2  (1/506) N/A
Forelimb 2  (1/506)  (2/2) N/A
Fronto-nasal process 2  (1/62) Image Only N/A
Hand 2  (1/506)  (2/2) N/A
Head 2  (5/506)  (2/2) N/A
Heart 2  (1/506)  (2/2) N/A
Hindbrain 2  (6/506)  (1/2) N/A
Hindlimb 2  (1/506)  (2/2) N/A
Liver 2  (1/504) N/A
Lung 2  (1/504) Image Only N/A
Mandibular process 2  (1/506)  (2/2) N/A
Maxillary process 2  (1/506)  (1/2) N/A
Midbrain 2  (1/506) N/A
Nose 2  (1/76)  (1/2) N/A
Oral cavity 2  (1/504) Image Only N/A
Skin 2  (1/506) Image Only N/A
Spinal cord 2  (1/73)  (1/2) N/A
Tail 2  (1/506)  (2/2) N/A
Tail somite 2  (1/506) N/A
embryo or Unassigned (8)
Embryo expression
EMAPA:16039 embryo

 Associated Images

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Original Image
Adult LacZ: LacZ Images Section
40 Images
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X-ray: XRay Images Skull Lateral Orientation
10 Images
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X-ray: XRay Images Whole Body Dorso Ventral
10 Images
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Embryo LacZ: LacZ images wholemount
8 Images
thumbnail
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
thumbnail
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
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X-ray: XRay Images Forepaw
10 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Mrpl22tm1b(KOMP)Mbp Reporter-tagged deletion allele (post-Cre) Mice
Mrpl22tm2a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Mrpl22tm41846(L1L2_gt2) Targeting vectors
Mrpl22tm1a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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