Phenotype | System | Allele | Zyg | Sex | Life Stage | P Value |
---|---|---|---|---|---|---|
abnormal behavior | Mrpl22tm1b(KOMP)Mbp | HET | Early adult | 6.94×10-05 | ||
embryonic lethality prior to organogenesis | Mrpl22tm1b(KOMP)Mbp | HOM | E9.5 | 0.00 | ||
decreased thigmotaxis | Mrpl22tm1b(KOMP)Mbp | HET | Early adult | 6.94×10-05 | ||
preweaning lethality, complete penetrance | Mrpl22tm1b(KOMP)Mbp | HOM | Early adult | 0.00 | ||
impaired pupillary reflex | Mrpl22tm1b(KOMP)Mbp | HET | Early adult | 1.41×10-05 |
Gene: Mrpl22
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IMPC lacZ Expression Data
Anatomy | #HET Specimens | HOM Images? | WT Expr | Mutant Expr | Images |
---|---|---|---|---|---|
Adrenal gland | 2 | No | (3/590) | (2/2) | Section images |
Aorta | 2 | No | (1/590) | (2/2) | Section images |
Brain | 2 | No | (3/590) | (2/2) | Section images |
Brainstem | 2 | No | (2/590) | (2/2) | Section images |
Brown adipose tissue | 2 | No | N/A | ||
Cartilage tissue | 2 | No | (2/2) | Section images | |
Cerebellum | 2 | No | (3/590) | (2/2) | Section images |
Cerebral cortex | 2 | No | (2/590) | (2/2) | Section images |
Epididymis | 2 | No | (18/134) | (1/2) | Section images |
Esophagus | 2 | No | (7/415) | (2/2) | Section images |
Eye | 2 | No | (2/2) | Section images | |
Heart | 2 | No | (1/590) | (2/2) | Section images |
Hippocampus | 2 | No | (3/590) | (2/2) | Section images |
Hypothalamus | 2 | No | (2/590) | (2/2) | Section images |
Kidney | 2 | No | (20/590) | (2/2) | Section images |
Large intestine | 2 | No | (10/590) | (2/2) | Section images |
Liver | 2 | No | (2/2) | Section images | |
Lower urinary tract | 2 | No | (1/590) | N/A | |
Lung | 2 | No | (1/590) | (2/2) | Section images |
Lymph node | 2 | No | N/A | ||
Mammary gland | 2 | No | N/A | ||
Midbrain | 2 | No | (2/2) | Section images | |
Olfactory lobe | 2 | No | (2/590) | (2/2) | Section images |
Ovary | 2 | No | (1/590) | Section images | |
Oviduct | 2 | No | (1/2) | Section images | |
Pancreas | 2 | No | (5/590) | (2/2) | Section images |
Peripheral nervous system | 2 | No | (1/590) | (2/2) | Section images |
Peyer's patch | 2 | No | Section images | ||
Pituitary gland | 2 | No | (1/590) | (2/2) | Section images |
Prostate gland | 2 | No | (12/590) | N/A | |
Skeletal muscle | 2 | No | (2/2) | Section images | |
Skin | 2 | No | (2/2) | Section images | |
Small intestine | 2 | No | (9/590) | (2/2) | Section images |
Spinal cord | 2 | No | (2/590) | (2/2) | Section images |
Spleen | 2 | No | (2/590) | (2/2) | Section images |
Stomach | 2 | No | (13/590) | (2/2) | Section images |
Striatum | 2 | No | (3/590) | (2/2) | Section images |
Submandibular gland | 2 | No | (2/132) | Section images | |
Testis | 2 | No | (5/590) | (1/2) | Section images |
Thalamus | 2 | No | (2/2) | Section images | |
Thymus | 2 | No | N/A | ||
Thyroid gland | 2 | No | (16/590) | (2/2) | Section images |
Trachea | 2 | No | (2/590) | N/A | |
Urinary bladder | 2 | No | (2/2) | Section images | |
Uterus | 2 | No | (1/2) | Section images | |
Vascular system | 2 | No | (2/2) | Section images | |
Vesicular gland | 2 | No | N/A | ||
White adipose tissue | 2 | No | (2/2) | Section images |
LacZ Wholemount Images
LacZ Section Images
Anatomy | #HET Specimens | WT Expr | Mutant Expr | Images |
---|---|---|---|---|
Brain | 2 | (6/506) | (1/2) | N/A |
Dorsal root ganglion | 2 | (1/61) | Image Only | N/A |
Ear | 2 | (1/506) | N/A | |
Embryo | 2 | (1/507) | (2/2) | Wholemount images |
Eye | 2 | (1/506) | (2/2) | N/A |
Foot | 2 | (1/506) | (2/2) | N/A |
Forebrain | 2 | (1/506) | N/A | |
Forelimb | 2 | (1/506) | (2/2) | N/A |
Fronto-nasal process | 2 | (1/62) | Image Only | N/A |
Hand | 2 | (1/506) | (2/2) | N/A |
Head | 2 | (5/506) | (2/2) | N/A |
Heart | 2 | (1/506) | (2/2) | N/A |
Hindbrain | 2 | (6/506) | (1/2) | N/A |
Hindlimb | 2 | (1/506) | (2/2) | N/A |
Liver | 2 | (1/504) | N/A | |
Lung | 2 | (1/504) | Image Only | N/A |
Mandibular process | 2 | (1/506) | (2/2) | N/A |
Maxillary process | 2 | (1/506) | (1/2) | N/A |
Midbrain | 2 | (1/506) | N/A | |
Nose | 2 | (1/76) | (1/2) | N/A |
Oral cavity | 2 | (1/504) | Image Only | N/A |
Skin | 2 | (1/506) | Image Only | N/A |
Spinal cord | 2 | (1/73) | (1/2) | N/A |
Tail | 2 | (1/506) | (2/2) | N/A |
Tail somite | 2 | (1/506) | N/A |
Associated Images
Disease Models
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MGI Allele | Allele Type | Produced |
---|---|---|
Mrpl22tm1b(KOMP)Mbp | Reporter-tagged deletion allele (post-Cre) | Mice |
Mrpl22tm2a(KOMP)Mbp | KO first allele (reporter-tagged insertion with conditional potential) | Targeting vectors, ES Cells |
Mrpl22tm41846(L1L2_gt2) | Targeting vectors | |
Mrpl22tm1a(KOMP)Mbp | KO first allele (reporter-tagged insertion with conditional potential) | Mice, Targeting vectors, ES Cells |
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