Genes Phenotypes

Gene: Mrpl22

Name
mitochondrial ribosomal protein L22
MGI ID
MGI:1333794
Synonyms
HSPC158 Rpml25 E030011D16Rik MRP-L25
Viability
Homozygous - Lethal
Other links
MGI   Ensembl  
Significant phenotypes (2) All measurements (153) Expression & images (73) Disease models (0) Order (4)
View data by physiological system
Significant
Not Significant
Not tested
Body weight
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Mrpl22tm1b(KOMP)Mbp HOM n/a 0.00
impaired pupillary reflex Mrpl22tm1b(KOMP)Mbp HET postnatal 7.67×10-08

Download data as:  TSV  XLS

Filtered by: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Section images
Aorta 2 No  (2/2) N/A
Brain 2 No  (2/2)  Section images
Brainstem 2 No  (2/2)  Section images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2)  Section images
Cerebellum 2 No  (2/2)  Section images
Cerebral cortex 2 No  (2/2)  Section images
Epididymis 2 No  (18/134)  (1/2)  Section images
Esophagus 2 No  (7/415)  (2/2)  Section images
Eye 2 No  (2/2)  Section images
Heart 2 No  (2/2) N/A
Hippocampus 2 No  (2/2)  Section images
Hypothalamus 2 No  (2/2)  Section images
Kidney 2 No  (18/584)  (2/2)  Section images
Large intestine 2 No  (10/584)  (2/2)  Section images
Liver 2 No  (2/2)  Section images
Lower urinary tract 2 No N/A
Lung 2 No  (2/2)  Section images
Lymph node 2 No N/A
Mammary gland 2 No N/A
Midbrain 2 No  (2/2)  Section images
Olfactory lobe 2 No  (2/2)  Section images
Ovary 2 No  (1/584) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584)  (2/2)  Section images
Peripheral nervous system 2 No  (2/2)  Section images
Peyer's patch 2 No  Section images
Pituitary gland 2 No  (2/2)  Section images
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No  (2/2) N/A
Skin 2 No  (2/2)  Section images
Small intestine 2 No  (9/584)  (2/2)  Section images
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584)  (2/2)  Section images
Stomach 2 No  (12/584)  (2/2) N/A
Striatum 2 No  (2/2)  Section images
Submandibular gland 2 No  (2/132)  Section images
Testis 2 No  (2/584)  (1/2)  Section images
Thalamus 2 No  (2/2)  Section images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584)  (2/2) N/A
Trachea 2 No N/A
Urinary bladder 2 No  (2/2) N/A
Uterus 2 No  (1/2) N/A
Vascular system 2 No  (2/2) N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No  (2/2) N/A
LacZ Wholemount Images
LacZ Section Images
digestive system (6)
Esophagus expression
MA:0000352
endocrine system (1)
Adrenal gland expression
MA:0000116
exocrine system (1)
Submandibular Gland imageOnly
MA:0001589
immune system (2)
Peyers Patch imageOnly
MA:0000137
integumental system (1)
Skin expression
MA:0000151
nervous system (12)
Brain expression
MA:0000168
postnatal mouse (28)
Adrenal gland expression
MA:0000116
reproductive system (2)
Epididymis expression
MA:0000397
respiratory system (2)
Lung expression
MA:0000415
sensory organ (1)
Eye expression
MA:0000261
set of connective tissues (1)
Cartilage tissue expression
MA:0000104
trunk (12)
Adrenal gland expression
MA:0000116
urinary system (1)
Kidney expression
MA:0000368
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485)  (1/2) N/A
Dorsal root ganglion 2  (1/47) Image Only N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485)  (2/2)  Wholemount images
Eye 2  (1/485)  (2/2) N/A
Foot 2  (1/485)  (2/2) N/A
Forebrain 2  (1/485) N/A
Forelimb 2  (1/485)  (2/2) N/A
Fronto-nasal process 2  (1/48) Image Only N/A
Hand 2  (1/485)  (2/2) N/A
Head 2  (5/485)  (2/2) N/A
Heart 2  (1/485)  (2/2) N/A
Hindbrain 2  (6/485)  (1/2) N/A
Hindlimb 2  (1/485)  (2/2) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485) Image Only N/A
Mandibular process 2  (1/485)  (2/2) N/A
Maxillary process 2  (1/485)  (1/2) N/A
Midbrain 2  (1/485) N/A
Nose 2  (1/51)  (1/2) N/A
Oral cavity 2  (1/485) Image Only N/A
Skin 2  (1/485) Image Only N/A
Spinal cord 2  (1/50)  (1/2) N/A
Tail 2  (1/485)  (2/2) N/A
Tail somite 2  (1/485) N/A
embryo or Unassigned (4)
Embryo expression
EMAPA:16039 embryo

 Associated Images

X-ray: XRay Images Lateral Orientation
6 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
6 Images
Original Image
Adult LacZ: LacZ Images Section
28 Images
X-ray: XRay Images Forepaw
6 Images
X-ray: XRay Images Dorso Ventral
6 Images
X-ray: XRay Images Skull Lateral Orientation
6 Images
Embryo LacZ: LacZ images wholemount
4 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Mrpl22tm1a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Mrpl22tm1b(KOMP)Mbp Reporter-tagged deletion allele (post-Cre) Mice
Mrpl22tm2a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Mrpl22tm41846(L1L2_gt2) Targeting vectors

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