Gene: Aqp3

Log in to follow

Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating alkaline phosphatase level Aqp3tm2b(EUCOMM)Wtsi HOM Early adult 1.62×10-13
increased circulating cholesterol level Aqp3tm2b(EUCOMM)Wtsi HOM Early adult 5.18×10-05
increased blood urea nitrogen level Aqp3tm2b(EUCOMM)Wtsi HOM Early adult 2.58×10-11
increased circulating creatinine level Aqp3tm2b(EUCOMM)Wtsi HOM Early adult 1.73×10-06
decreased bone mineral density Aqp3tm2b(EUCOMM)Wtsi HOM Early adult 7.90×10-05
increased circulating serum albumin level Aqp3tm2b(EUCOMM)Wtsi HOM Early adult 3.76×10-06
increased circulating total protein level Aqp3tm2b(EUCOMM)Wtsi HOM Early adult 3.45×10-06
increased circulating HDL cholesterol level Aqp3tm2b(EUCOMM)Wtsi HOM Early adult 2.12×10-05
decreased bone mineral content Aqp3tm2b(EUCOMM)Wtsi HOM Early adult 5.92×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (2/2)  Wholemount images
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No N/A
Oral epithelium 2 No  (2/2)  Wholemount images
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No  (2/2)  Wholemount images
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Wholemount images
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No  (2/2)  Wholemount images
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No  (2/2)  Wholemount images
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1  (6/504) N/A
Ear 1  (1/504) N/A
Embryo 1  (1/505) N/A
Eye 1  (1/504) N/A
Foot 1  (1/504) N/A
Forebrain 1  (1/504) N/A
Forelimb 1  (1/504) N/A
Hand 1  (1/503) N/A
Head 1  (5/504) N/A
Heart 1  (1/504) N/A
Hindbrain 1  (6/504) N/A
Hindlimb 1  (1/503) N/A
Liver 1  (1/504) N/A
Lung 1  (1/500) N/A
Mandibular process 1  (1/504) N/A
Maxillary process 1  (1/504) N/A
Midbrain 1  (1/504) N/A
Oral cavity 1  (1/504) N/A
Skin 1  (1/504) N/A
Tail 1  (1/504) N/A
Tail somite 1  (1/504) N/A

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
Embryo LacZ: LacZ images wholemount
4 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Adult LacZ: LacZ Images Wholemount
7 Images
Echo: M-Mode Images
32 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Kidney - atrophy Aqp3tm2b(EUCOMM)Wtsi HOM Early adult
Kidney - MPATH diagnostic term hydronephrosis Aqp3tm2b(EUCOMM)Wtsi HOM Early adult
Urinary bladder - dilatation Aqp3tm2b(EUCOMM)Wtsi HOM Early adult

 Order Mouse and ES Cells

This service may be affected by the Covid-19 pandemic. See how

MGI Allele Allele Type Produced
Aqp3tm2a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Aqp3tm2b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Aqp3tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Aqp3tm213839(pL1L2_GT0_DelLacZ_bsd) Targeting vectors

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter