Gene: Aqp3

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Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating total protein level Aqp3tm2b(EUCOMM)Wtsi HOM Early adult 6.14×10-07
increased circulating alkaline phosphatase level Aqp3tm2b(EUCOMM)Wtsi HOM Early adult 6.53×10-14
increased circulating serum albumin level Aqp3tm2b(EUCOMM)Wtsi HOM Early adult 6.51×10-07
increased circulating creatinine level Aqp3tm2b(EUCOMM)Wtsi HOM Early adult 3.17×10-06
increased circulating HDL cholesterol level Aqp3tm2b(EUCOMM)Wtsi HOM   Early adult 1.76×10-05
increased circulating cholesterol level Aqp3tm2b(EUCOMM)Wtsi HOM   Early adult 4.54×10-05
increased blood urea nitrogen level Aqp3tm2b(EUCOMM)Wtsi HOM Early adult 1.83×10-11

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583) N/A
Aorta 2 No  (1/583) N/A
Bone 2 No N/A
Brain 2 No  (4/583) N/A
Brainstem 2 No  (2/583) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/583) N/A
Cerebellum 2 No  (3/583) N/A
Cerebral cortex 2 No  (2/583) N/A
Esophagus 2 No  (7/407) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (2/583) N/A
Hippocampus 2 No  (3/583) N/A
Hypothalamus 2 No  (2/583) N/A
Kidney 2 No  (21/583)  (2/2)  Wholemount images
Large intestine 2 No  (10/583) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/583)  (2/2)  Wholemount images
Lung 2 No  (2/583) N/A
Lymph node 2 No  (1/583) N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/583) N/A
Oral epithelium 2 No  (2/2)  Wholemount images
Ovary 2 No  (1/583) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/583) N/A
Parathyroid gland 2 No  (1/563)  (2/2)  Wholemount images
Peripheral nervous system 2 No  (2/583) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/583) N/A
Prostate gland 2 No  (12/583) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (1/583)  (2/2)  Wholemount images
Small intestine 2 No  (9/583) N/A
Spinal cord 2 No  (3/583) N/A
Spleen 2 No  (3/583) N/A
Stomach 2 No  (13/583) N/A
Striatum 2 No  (3/583) N/A
Testis 2 No  (6/583)  (1/2)  Wholemount images
Thymus 2 No  (1/583)  (2/2)  Wholemount images
Thyroid gland 2 No  (17/583) N/A
Trachea 2 No  (3/583)  (2/2)  Wholemount images
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
1  (6/505) N/A
1  (1/505) N/A
1  (1/506) N/A
1  (1/505) N/A
1  (1/505) N/A
1  (1/505) N/A
1  (1/505) N/A
1  (1/505) N/A
1  (5/505) N/A
1  (1/505) N/A
1  (6/505) N/A
1  (1/505) N/A
1  (1/503) N/A
1  (1/503) N/A
1  (1/505) N/A
1  (1/505) N/A
1  (1/505) N/A
1  (1/503) N/A
1  (1/505) N/A
1  (1/505) N/A
1  (1/505) N/A

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
10 Images
Echo: M-Mode Images
32 Images
Adult LacZ: LacZ Images Wholemount
7 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Embryo LacZ: LacZ images wholemount
4 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Aqp3tm2b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Aqp3tm213839(pL1L2_GT0_DelLacZ_bsd) Targeting vectors
Aqp3tm2a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Aqp3tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells

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