Gene: Dyrk1b

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
Homozygous - Lethal
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View data by physiological system
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased or absent threshold for auditory brainstem response Dyrk1btm1b(EUCOMM)Wtsi HET postnatal 0.00
preweaning lethality, complete penetrance Dyrk1btm1b(EUCOMM)Wtsi HOM n/a 0.00
increased neutrophil cell number Dyrk1btm1b(EUCOMM)Wtsi HET postnatal 3.99×10-05
decreased large unstained cell number Dyrk1btm1b(EUCOMM)Wtsi HET postnatal 5.09×10-05

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Expression data not available

 Associated Images

X-ray: XRay Images Lateral Orientation
10 Images
X-ray: XRay Images Dorso Ventral
10 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Dyrk1btm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Dyrk1btm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Dyrk1btm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells

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