Gene: Cdk9

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Name
cyclin-dependent kinase 9 (CDC2-related kinase)
MGI ID
MGI:1328368
Synonyms
PITALRE
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Cdk9tm1.1(KOMP)Vlcg HOM   Early adult 0.00
embryonic lethality prior to organogenesis Cdk9tm1.1(KOMP)Vlcg HOM   E9.5 0.00
enlarged heart Cdk9tm1.1(KOMP)Vlcg HET Early adult 0.00
abnormal heart morphology Cdk9tm1.1(KOMP)Vlcg HET Early adult 0.00
abnormal epididymis morphology Cdk9tm1.1(KOMP)Vlcg HET Early adult 0.00
embryonic lethality prior to tooth bud stage Cdk9tm1.1(KOMP)Vlcg HOM   E12.5 0.00
enlarged epididymis Cdk9tm1.1(KOMP)Vlcg HET Early adult 0.00
shortened RR interval Cdk9tm1.1(KOMP)Vlcg HET Early adult 7.24×10-12
increased heart rate Cdk9tm1.1(KOMP)Vlcg HET Early adult 1.82×10-10

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Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
2 No  (4/583)  (1/2)  Section images
2 No  (1/583)  (2/2)  Section images
2 No  (1/2)  Section images
2 No  (2/2)  Section images
2 No  (4/583) N/A
2 No  (2/583) N/A
2 No  (2/2)  Section images
2 No  (1/583) N/A
2 No  (12/371)  (2/2)  Section images
2 No  (3/583)  (2/2)  Section images
2 No  (2/583) N/A
2 No N/A
2 No  (12/127)  (2/2)  Section images
2 No  (1/2)  Section images
2 No  (2/127) N/A
2 No  (18/132)  (1/2)  Section images
2 No  (7/407)  (2/2)  Section images
2 No  (2/2)  Section images
2 No N/A
2 No  (1/2)  Section images
2 No  (2/2)  Section images
2 No  (2/583) N/A
2 No N/A
2 No  (3/583) N/A
2 No  (2/583) N/A
2 No  (14/127)  (2/2)  Section images
2 No  (6/127)  (2/2)  Section images
2 No  (21/583)  (2/2)  Section images
2 No  (10/583) N/A
2 No  (2/2)  Section images
2 No  (1/583) N/A
2 No  (2/583)  (2/2)  Section images
2 No  (1/583) N/A
2 No N/A
2 No  (2/2)  Section images
2 No  (2/2)  Section images
2 No  (2/2)  Section images
2 No  (2/583)  (2/2)  Section images
2 No  (1/583)  (1/2)  Section images
2 No  (1/2)  Section images
2 No  (5/583)  (2/2)  Section images
2 No  (1/563)  (2/2)  Section images
2 No  (2/2)  Section images
2 No  (1/2)  Section images
2 No  (2/583) N/A
2 No N/A
2 No  (1/583)  (1/2)  Section images
2 No  (12/583)  (1/2)  Section images
2 No  (2/2)  Section images
2 No  (1/2)  Section images
2 No N/A
2 No  (1/583)  (2/2)  Section images
2 No  (9/583) N/A
2 No  (3/583)  (2/2)  Section images
2 No  (3/583)  (2/2)  Section images
2 No  (13/583)  (2/2)  Section images
2 No N/A
2 No  (3/583) N/A
2 No  (2/2)  Section images
2 No  (2/130)  (2/2)  Section images
2 No  (6/583)  (1/2)  Section images
2 No  (1/583)  (2/2)  Section images
2 No  (17/583)  (2/2)  Section images
2 No  (5/127)  (2/2)  Section images
2 No  (3/583)  (2/2)  Section images
2 No  (1/2)  Section images
2 No  (2/2)  Section images
2 No  (1/2)  Section images
2 No N/A
2 No  (15/382)  (1/2)  Section images
2 No N/A
2 No  (1/2)  Section images
2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (1/64)  (2/2) N/A
7  (6/505)  (2/7) N/A
2  (1/73)  (2/2) N/A
7  (1/505)  (2/7) N/A
7  (1/506)  (2/7) N/A
7  (1/505)  (2/7) N/A
7  (1/505)  (2/7) N/A
7  (1/505)  (2/7) N/A
7  (1/505)  (2/7) N/A
2  (1/59)  (2/2) N/A
7  (1/505)  (2/7) N/A
7  (5/505)  (2/7) N/A
7  (1/505)  (2/7) N/A
7  (6/505)  (2/7) N/A
7  (1/505)  (2/7) N/A
7  (1/503)  (2/7) N/A
7  (1/503)  (2/7) N/A
7  (1/505)  (2/7) N/A
7  (1/505)  (2/7) N/A
7  (1/505)  (2/7) N/A
2  (1/75)  (2/2) N/A
7  (1/503)  (2/7) N/A
7  (7/39)  (7/7) N/A
2  (1/75)  (2/2) N/A
7  (1/505)  (2/7) N/A
2  (1/72)  (2/2) N/A
7  (1/505)  (2/7) N/A
7  (1/505)  (2/7) N/A
2  (1/59)  (2/2) N/A
2  (1/59)  (2/2) N/A

 Associated Images

Adult LacZ: LacZ Images Section
183 Images
X-ray: XRay Images Whole Body Lateral Orientation
11 Images
X-ray: XRay Images Forepaw
9 Images
Embryo LacZ: LacZ images wholemount
28 Images
X-ray: XRay Images Skull Lateral Orientation
9 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
9 Images
X-ray: XRay Images Whole Body Dorso Ventral
11 Images
X-ray: XRay Images Hind Leg and Hip
9 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Cdk9tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Cdk9tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Cdk9tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue

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