Trex1 | three prime repair exonuclease 1
Physiological systems
20 / 24 physiological systems tested
15 Significantly impacted by the knock-out
Reproductive system Immune system Endocrine/exocrine gland Integument Adipose tissue Growth/size/body region Hematopoietic system Cardiovascular system Craniofacial Renal/urinary system Homeostasis/metabolism Limbs/digits/tail Vision/eye Liver/biliary system Skeleton
5 No significant impact
4 Not tested
Data collections
Gene metrics:40Significant phenotypes
8Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues
Human diseases caused by Trex1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
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